Global, Regional, and National Burden of Myocarditis and Cardiomyopathy, 1990–2017
Objective: To estimate the burden of myocarditis (MC), alcoholic cardiomyopathy (AC), and other cardiomyopathy (OC) for 195 countries and territories from 1990 to 2017.Methods: We collected detailed information on MC, AC, and OC between 1990 and 2017 from the Global Burden of Disease study 2017, whi...
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Frontiers Media S.A.
2021-02-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2021.610989/full |
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| author | Haijiang Dai Haijiang Dai Dor Lotan Dor Lotan Arsalan Abu Much Arsalan Abu Much Arwa Younis Yao Lu Nicola Luigi Bragazzi Jianhong Wu |
| author_facet | Haijiang Dai Haijiang Dai Dor Lotan Dor Lotan Arsalan Abu Much Arsalan Abu Much Arwa Younis Yao Lu Nicola Luigi Bragazzi Jianhong Wu |
| author_sort | Haijiang Dai |
| collection | DOAJ |
| description | Objective: To estimate the burden of myocarditis (MC), alcoholic cardiomyopathy (AC), and other cardiomyopathy (OC) for 195 countries and territories from 1990 to 2017.Methods: We collected detailed information on MC, AC, and OC between 1990 and 2017 from the Global Burden of Disease study 2017, which was designed to provide a systematic assessment of health loss due to diseases and injuries in 21 regions, covering 195 countries and territories. Estimates of MC, AC, and OC burden were produced using a standard Cause of Death Ensemble model and a Bayesian mixed-effects meta-regression tool, and included prevalence, deaths, years lived with disability (YLDs), and years of life lost (YLLs). All estimates were presented as counts, age-standardized rates per 100,000 people and percentage change, with 95% uncertainty intervals (UIs).Results: Worldwide, there were 1.80 million (95% UI 1.64–1.98) cases of MC, 1.62 million (95% UI 1.37–1.90) cases of AC and 4.21 million (95% UI 3.63–4.87) cases of OC, contributing to 46,486 (95% UI 39,709–51,824), 88,890 (95% UI 80,935–96,290), and 233,159 (95% UI 213,677–248,289) deaths in 2017, respectively. Furthermore, globally, there were 131,376 (95% UI 90,113–183,001) YLDs and 1.26 million (95% UI 1.10–1.42) YLLs attributable to MC, 139,087 (95% UI 95,134–196,130) YLDs and 2.84 million (95% UI 2.60–3.07) YLLs attributable to AC, and 353,325 (95% UI 237,907–493,908) YLDs and 5.51 million (95% UI 4.95–5.99) YLLs attributable to OC in 2017. At the national level, the age-standardized prevalence rates varied by 10.4 times for MC, 252.6 times for AC and 38.1 times for OC; the age-standardized death rates varied by 43.9 times for MC, 531.0 times for AC and 43.3 times for OC; the age-standardized YLD rates varied by 12.4 times for MC, 223.7 times for AC, and 34.1 times for OC; and the age-standardized YLL rates varied by 38.4 times for MC, 684.8 times for AC, and 36.2 times for OC. Between 1990 and 2017, despite the decreases in age-standardized rates, the global numbers of prevalent cases, deaths, YLDs, and YLLs have increased for all the diseases.Conclusion: Accurate assessment of the burden of MC, AC, and OC is essential for formulating effective preventative prevention and treatment programs and optimizing health system resource allocation. Our results suggest that MC, AC, and OC remain important global public health problems with increasing numbers of prevalent cases, deaths, YLDs, and YLLs over the past decades, and there are significant geographic variations in the burden of these diseases. Further research is warranted to expand our knowledge of potential risk factors and to improve the prevention, early detection and treatment of these diseases. |
| first_indexed | 2024-12-14T19:57:10Z |
| format | Article |
| id | doaj.art-6bbbb187c868453691a6aea669b0caae |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-12-14T19:57:10Z |
| publishDate | 2021-02-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-6bbbb187c868453691a6aea669b0caae2022-12-21T22:49:17ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2021-02-01810.3389/fcvm.2021.610989610989Global, Regional, and National Burden of Myocarditis and Cardiomyopathy, 1990–2017Haijiang Dai0Haijiang Dai1Dor Lotan2Dor Lotan3Arsalan Abu Much4Arsalan Abu Much5Arwa Younis6Yao Lu7Nicola Luigi Bragazzi8Jianhong Wu9Department of Cardiology, The Third Xiangya Hospital, Central South University, Changsha, ChinaCentre for Disease Modelling, Department of Mathematics and Statistics, York University, Toronto, ON, CanadaLeviev Heart Center, Sheba Medical Center, Ramat Gan, IsraelSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, IsraelLeviev Heart Center, Sheba Medical Center, Ramat Gan, IsraelSackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, IsraelClinical Cardiovascular Research Center, University of Rochester Medical Center, Rochester, NY, United StatesDepartment of Cardiology, The Third Xiangya Hospital, Central South University, Changsha, ChinaCentre for Disease Modelling, Department of Mathematics and Statistics, York University, Toronto, ON, CanadaCentre for Disease Modelling, Department of Mathematics and Statistics, York University, Toronto, ON, CanadaObjective: To estimate the burden of myocarditis (MC), alcoholic cardiomyopathy (AC), and other cardiomyopathy (OC) for 195 countries and territories from 1990 to 2017.Methods: We collected detailed information on MC, AC, and OC between 1990 and 2017 from the Global Burden of Disease study 2017, which was designed to provide a systematic assessment of health loss due to diseases and injuries in 21 regions, covering 195 countries and territories. Estimates of MC, AC, and OC burden were produced using a standard Cause of Death Ensemble model and a Bayesian mixed-effects meta-regression tool, and included prevalence, deaths, years lived with disability (YLDs), and years of life lost (YLLs). All estimates were presented as counts, age-standardized rates per 100,000 people and percentage change, with 95% uncertainty intervals (UIs).Results: Worldwide, there were 1.80 million (95% UI 1.64–1.98) cases of MC, 1.62 million (95% UI 1.37–1.90) cases of AC and 4.21 million (95% UI 3.63–4.87) cases of OC, contributing to 46,486 (95% UI 39,709–51,824), 88,890 (95% UI 80,935–96,290), and 233,159 (95% UI 213,677–248,289) deaths in 2017, respectively. Furthermore, globally, there were 131,376 (95% UI 90,113–183,001) YLDs and 1.26 million (95% UI 1.10–1.42) YLLs attributable to MC, 139,087 (95% UI 95,134–196,130) YLDs and 2.84 million (95% UI 2.60–3.07) YLLs attributable to AC, and 353,325 (95% UI 237,907–493,908) YLDs and 5.51 million (95% UI 4.95–5.99) YLLs attributable to OC in 2017. At the national level, the age-standardized prevalence rates varied by 10.4 times for MC, 252.6 times for AC and 38.1 times for OC; the age-standardized death rates varied by 43.9 times for MC, 531.0 times for AC and 43.3 times for OC; the age-standardized YLD rates varied by 12.4 times for MC, 223.7 times for AC, and 34.1 times for OC; and the age-standardized YLL rates varied by 38.4 times for MC, 684.8 times for AC, and 36.2 times for OC. Between 1990 and 2017, despite the decreases in age-standardized rates, the global numbers of prevalent cases, deaths, YLDs, and YLLs have increased for all the diseases.Conclusion: Accurate assessment of the burden of MC, AC, and OC is essential for formulating effective preventative prevention and treatment programs and optimizing health system resource allocation. Our results suggest that MC, AC, and OC remain important global public health problems with increasing numbers of prevalent cases, deaths, YLDs, and YLLs over the past decades, and there are significant geographic variations in the burden of these diseases. Further research is warranted to expand our knowledge of potential risk factors and to improve the prevention, early detection and treatment of these diseases.https://www.frontiersin.org/articles/10.3389/fcvm.2021.610989/fullmyocarditiscardiomyopathyglobal burden of diseaseprevalencemortality |
| spellingShingle | Haijiang Dai Haijiang Dai Dor Lotan Dor Lotan Arsalan Abu Much Arsalan Abu Much Arwa Younis Yao Lu Nicola Luigi Bragazzi Jianhong Wu Global, Regional, and National Burden of Myocarditis and Cardiomyopathy, 1990–2017 Frontiers in Cardiovascular Medicine myocarditis cardiomyopathy global burden of disease prevalence mortality |
| title | Global, Regional, and National Burden of Myocarditis and Cardiomyopathy, 1990–2017 |
| title_full | Global, Regional, and National Burden of Myocarditis and Cardiomyopathy, 1990–2017 |
| title_fullStr | Global, Regional, and National Burden of Myocarditis and Cardiomyopathy, 1990–2017 |
| title_full_unstemmed | Global, Regional, and National Burden of Myocarditis and Cardiomyopathy, 1990–2017 |
| title_short | Global, Regional, and National Burden of Myocarditis and Cardiomyopathy, 1990–2017 |
| title_sort | global regional and national burden of myocarditis and cardiomyopathy 1990 2017 |
| topic | myocarditis cardiomyopathy global burden of disease prevalence mortality |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2021.610989/full |
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