Antimicrobial Nanomaterials: Why Evolution Matters
Due to the widespread occurrence of multidrug resistant microbes there is increasing interest in the use of novel nanostructured materials as antimicrobials. Specifically, metallic nanoparticles such as silver, copper, and gold have been deployed due to the multiple impacts they have on bacterial ph...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2017-09-01
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| Series: | Nanomaterials |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2079-4991/7/10/283 |
| _version_ | 1819158174543904768 |
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| author | Joseph L. Graves Misty Thomas Jude Akamu Ewunkem |
| author_facet | Joseph L. Graves Misty Thomas Jude Akamu Ewunkem |
| author_sort | Joseph L. Graves |
| collection | DOAJ |
| description | Due to the widespread occurrence of multidrug resistant microbes there is increasing interest in the use of novel nanostructured materials as antimicrobials. Specifically, metallic nanoparticles such as silver, copper, and gold have been deployed due to the multiple impacts they have on bacterial physiology. From this, many have concluded that such nanomaterials represent steep obstacles against the evolution of resistance. However, we have already shown that this view is fallacious. For this reason, the significance of our initial experiments are beginning to be recognized in the antimicrobial effects of nanomaterials literature. This recognition is not yet fully understood and here we further explain why nanomaterials research requires a more nuanced understanding of core microbial evolution principles. |
| first_indexed | 2024-12-22T16:20:28Z |
| format | Article |
| id | doaj.art-6bbd737c7cef40cbb98f33401540afea |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-12-22T16:20:28Z |
| publishDate | 2017-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-6bbd737c7cef40cbb98f33401540afea2022-12-21T18:20:15ZengMDPI AGNanomaterials2079-49912017-09-0171028310.3390/nano7100283nano7100283Antimicrobial Nanomaterials: Why Evolution MattersJoseph L. Graves0Misty Thomas1Jude Akamu Ewunkem2Department of Nanoengineering, Joint School of Nanoscience & Nanoengineering, North Carolina A&T State University and UNC Greensboro, Greensboro, NC 27401, USADepartment of Biology, North Carolina A&T State University, Greensboro, NC 27411, USADepartment of Nanoengineering, Joint School of Nanoscience & Nanoengineering, North Carolina A&T State University and UNC Greensboro, Greensboro, NC 27401, USADue to the widespread occurrence of multidrug resistant microbes there is increasing interest in the use of novel nanostructured materials as antimicrobials. Specifically, metallic nanoparticles such as silver, copper, and gold have been deployed due to the multiple impacts they have on bacterial physiology. From this, many have concluded that such nanomaterials represent steep obstacles against the evolution of resistance. However, we have already shown that this view is fallacious. For this reason, the significance of our initial experiments are beginning to be recognized in the antimicrobial effects of nanomaterials literature. This recognition is not yet fully understood and here we further explain why nanomaterials research requires a more nuanced understanding of core microbial evolution principles.https://www.mdpi.com/2079-4991/7/10/283Antimicrobialsmetalsacclimationadaptationevolutiongenomics |
| spellingShingle | Joseph L. Graves Misty Thomas Jude Akamu Ewunkem Antimicrobial Nanomaterials: Why Evolution Matters Nanomaterials Antimicrobials metals acclimation adaptation evolution genomics |
| title | Antimicrobial Nanomaterials: Why Evolution Matters |
| title_full | Antimicrobial Nanomaterials: Why Evolution Matters |
| title_fullStr | Antimicrobial Nanomaterials: Why Evolution Matters |
| title_full_unstemmed | Antimicrobial Nanomaterials: Why Evolution Matters |
| title_short | Antimicrobial Nanomaterials: Why Evolution Matters |
| title_sort | antimicrobial nanomaterials why evolution matters |
| topic | Antimicrobials metals acclimation adaptation evolution genomics |
| url | https://www.mdpi.com/2079-4991/7/10/283 |
| work_keys_str_mv | AT josephlgraves antimicrobialnanomaterialswhyevolutionmatters AT mistythomas antimicrobialnanomaterialswhyevolutionmatters AT judeakamuewunkem antimicrobialnanomaterialswhyevolutionmatters |