Comparison between a deep-learning and a pixel-based approach for the automated quantification of HIV target cells in foreskin tissue
Abstract The availability of target cells expressing the HIV receptors CD4 and CCR5 in genital tissue is a critical determinant of HIV susceptibility during sexual transmission. Quantification of immune cells in genital tissue is therefore an important outcome for studies on HIV susceptibility and p...
Main Authors: | Zhongtian Shao, Lane B. Buchanan, David Zuanazzi, Yazan N. Khan, Ali R. Khan, Jessica L. Prodger |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2024-01-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-024-52613-3 |
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