Killing of Brain Tumor Cells by Hypoxia-Responsive Element Mediated Expression of BAX

Killing of Brain Tumor Cells by Hypoxia-Responsive Element Mediated Expression of BAX

The presence of radioresistant hypoxic cells in human brain tumors limits the overall effectiveness of conventional fractionated radiation therapy. Tumor-specific therapies that target hypoxic cells are clearly needed. We have investigated the expression of suicide genes under hypoxia by a hypoxia-r...

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Bibliographic Details
Main Authors:	Hangjun Ruan, Jingli Wang, Lily Hu, Ching-Shwun Lin, Kathleen R. Lamborn, Dennis F. Deen
Format:	Article
Language:	English
Published:	Elsevier 1999-11-01
Series:	Neoplasia: An International Journal for Oncology Research
Subjects:	hypoxia brain tumor cells hypoxia-responsive element BAX suicide gene
Online Access:	http://www.sciencedirect.com/science/article/pii/S1476558699800141

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