TLR4 Asp299Gly and Thr399Ile polymorphisms: no impact on human immune responsiveness to LPS or respiratory syncytial virus.

TLR4 Asp299Gly and Thr399Ile polymorphisms: no impact on human immune responsiveness to LPS or respiratory syncytial virus.

A broad variety of natural environmental stimuli, genotypic influences and timing all contribute to expression of protective versus maladaptive immune responses and the resulting clinical outcomes in humans. The role of commonly co-segregating Toll-like receptor 4 (TLR4) non-synonymous single nucleo...

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Bibliographic Details
Main Authors:	Renée N Douville, Yuriy Lissitsyn, Aaron F Hirschfeld, Allan B Becker, Anita L Kozyrskyj, Joel Liem, Nathalie Bastien, Yan Li, Rachel E Victor, Mehtab Sekhon, Stuart E Turvey, Kent T HayGlass
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-08-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2919413?pdf=render

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