Ceftriaxone Treatment Weakens Long-Term Synaptic Potentiation in the Hippocampus of Young Rats

Ceftriaxone Treatment Weakens Long-Term Synaptic Potentiation in the Hippocampus of Young Rats

Disrupted glutamate clearance in the synaptic cleft leads to synaptic dysfunction and neurological diseases. Decreased glutamate removal from the synaptic cleft is known to cause excitotoxicity. Data on the physiological effects of increased glutamate clearance are contradictory. This study investig...

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Bibliographic Details
Main Authors: Tatyana Y. Postnikova, Sergey L. Malkin, Maria V. Zakharova, Ilya V. Smolensky, Olga E. Zubareva, Aleksey V. Zaitsev
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
long-term potentiation
NMDA receptor
hippocampus
EAAT2
memory
Online Access:https://www.mdpi.com/1422-0067/22/16/8417

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