Physical Exercise and Mitochondrial Disease: Insights From a Mouse Model

Physical Exercise and Mitochondrial Disease: Insights From a Mouse Model

Purpose: Mitochondrial diseases (MD) are among the most prevalent neuromuscular disorders. Unfortunately, no curative treatment is yet available. This study analyzed the effects of exercise training in an animal model of respiratory chain complex I deficiency, the Harlequin (Hq) mouse, which replica...

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Bibliographic Details
Main Authors: Carmen Fiuza-Luces, Pedro L. Valenzuela, Sara Laine-Menéndez, Miguel Fernández-de la Torre, Verónica Bermejo-Gómez, Laura Rufián-Vázquez, Joaquín Arenas, Miguel A. Martín, Alejandro Lucia, María Morán
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Neurology
Subjects:
rare diseases
mitochondrial diseases
OXPHOS
harlequin mutant mouse
resistance training
AIF deficiency
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00790/full

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