The hippocampus supports multiple cognitive processes through relational binding and comparison
It has been well established that the hippocampus plays a pivotal role in explicit long-term recognition memory. However, findings from amnesia, lesion and recording studies with non-human animals, eye-movement recording studies, and functional neuroimaging have recently converged upon a similar me...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2012-05-01
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| Series: | Frontiers in Human Neuroscience |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fnhum.2012.00146/full |
| _version_ | 1818579491759325184 |
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| author | Rosanna Kathleen Olsen Sandra N. Moses Sandra N. Moses Sandra N. Moses Lily eRiggs Lily eRiggs Jennifer D Ryan Jennifer D Ryan Jennifer D Ryan |
| author_facet | Rosanna Kathleen Olsen Sandra N. Moses Sandra N. Moses Sandra N. Moses Lily eRiggs Lily eRiggs Jennifer D Ryan Jennifer D Ryan Jennifer D Ryan |
| author_sort | Rosanna Kathleen Olsen |
| collection | DOAJ |
| description | It has been well established that the hippocampus plays a pivotal role in explicit long-term recognition memory. However, findings from amnesia, lesion and recording studies with non-human animals, eye-movement recording studies, and functional neuroimaging have recently converged upon a similar message: the functional reach of the hippocampus extends far beyond explicit recognition memory. Damage to the hippocampus affects performance on a number of cognitive tasks including recognition memory after short and long delays and visual discrimination. Additionally, with the advent of neuroimaging techniques that have fine spatial and temporal resolution, findings have emerged that show the elicitation of hippocampal responses within the first few hundred milliseconds of stimulus/task onset. These responses occur for novel and previously viewed information during a time when perceptual processing is traditionally thought to occur, and long before overt recognition responses are made. We propose that the hippocampus is obligatorily involved in the binding of disparate elements across both space and time, and in the comparison of such relational memory representations. Furthermore, the hippocampus supports relational binding and comparison with or without conscious awareness for the relational representations that are formed, retrieved and/or compared. It is by virtue of these basic binding and comparison functions that the reach of the hippocampus extends beyond long-term recognition memory and underlies task performance in multiple cognitive domains. |
| first_indexed | 2024-12-16T07:02:33Z |
| format | Article |
| id | doaj.art-6bcc8ecf962d41cb934da7245b9714bb |
| institution | Directory Open Access Journal |
| issn | 1662-5161 |
| language | English |
| last_indexed | 2024-12-16T07:02:33Z |
| publishDate | 2012-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Human Neuroscience |
| spelling | doaj.art-6bcc8ecf962d41cb934da7245b9714bb2022-12-21T22:40:06ZengFrontiers Media S.A.Frontiers in Human Neuroscience1662-51612012-05-01610.3389/fnhum.2012.0014617384The hippocampus supports multiple cognitive processes through relational binding and comparisonRosanna Kathleen Olsen0Sandra N. Moses1Sandra N. Moses2Sandra N. Moses3Lily eRiggs4Lily eRiggs5Jennifer D Ryan6Jennifer D Ryan7Jennifer D Ryan8Rotman Research Institute at BaycrestRotman Research Institute at BaycrestHospital for Sick ChildrenUniversity of TorontoRotman Research Institute at BaycrestUniversity of TorontoRotman Research Institute at BaycrestUniversity of TorontoUniversity of TorontoIt has been well established that the hippocampus plays a pivotal role in explicit long-term recognition memory. However, findings from amnesia, lesion and recording studies with non-human animals, eye-movement recording studies, and functional neuroimaging have recently converged upon a similar message: the functional reach of the hippocampus extends far beyond explicit recognition memory. Damage to the hippocampus affects performance on a number of cognitive tasks including recognition memory after short and long delays and visual discrimination. Additionally, with the advent of neuroimaging techniques that have fine spatial and temporal resolution, findings have emerged that show the elicitation of hippocampal responses within the first few hundred milliseconds of stimulus/task onset. These responses occur for novel and previously viewed information during a time when perceptual processing is traditionally thought to occur, and long before overt recognition responses are made. We propose that the hippocampus is obligatorily involved in the binding of disparate elements across both space and time, and in the comparison of such relational memory representations. Furthermore, the hippocampus supports relational binding and comparison with or without conscious awareness for the relational representations that are formed, retrieved and/or compared. It is by virtue of these basic binding and comparison functions that the reach of the hippocampus extends beyond long-term recognition memory and underlies task performance in multiple cognitive domains.http://journal.frontiersin.org/Journal/10.3389/fnhum.2012.00146/fullAmnesiaVisual PerceptionbindingfMRIMEGrelational |
| spellingShingle | Rosanna Kathleen Olsen Sandra N. Moses Sandra N. Moses Sandra N. Moses Lily eRiggs Lily eRiggs Jennifer D Ryan Jennifer D Ryan Jennifer D Ryan The hippocampus supports multiple cognitive processes through relational binding and comparison Frontiers in Human Neuroscience Amnesia Visual Perception binding fMRI MEG relational |
| title | The hippocampus supports multiple cognitive processes through relational binding and comparison |
| title_full | The hippocampus supports multiple cognitive processes through relational binding and comparison |
| title_fullStr | The hippocampus supports multiple cognitive processes through relational binding and comparison |
| title_full_unstemmed | The hippocampus supports multiple cognitive processes through relational binding and comparison |
| title_short | The hippocampus supports multiple cognitive processes through relational binding and comparison |
| title_sort | hippocampus supports multiple cognitive processes through relational binding and comparison |
| topic | Amnesia Visual Perception binding fMRI MEG relational |
| url | http://journal.frontiersin.org/Journal/10.3389/fnhum.2012.00146/full |
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