Insights into Synonymous Codon Usage Bias in Hepatitis C Virus and Its Adaptation to Hosts

Insights into Synonymous Codon Usage Bias in Hepatitis C Virus and Its Adaptation to Hosts

Hepatitis C virus (HCV) is enveloped RNA virus, encoding for a polyprotein that is processed by cellular proteases. The virus is responsible for liver cirrhosis, allograft rejection, and human hepatocellular carcinoma. Based on studies including compositional analysis, odds ratio analysis, parity an...

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Bibliographic Details
Main Authors: Rekha Khandia, Azmat Ali Khan, Noushad Karuvantevida, Pankaj Gurjar, Igor Vladimirovich Rzhepakovsky, Isabel Legaz
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Pathogens
Subjects:
hepatitis C virus (HCV)
codon usage
liver cirrhosis
hepatocellular carcinoma
similarity index
relative codon deoptimization index
Online Access:https://www.mdpi.com/2076-0817/12/2/325

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