Human Population Density Influences Genetic Diversity of Two <i>Rattus</i> Species Worldwide: A Macrogenetic Approach
On a planet experiencing constant human population growth, it is necessary to explore the anthropogenic effects on the genetic diversity of species, and specifically invasive species. Using an analysis that integrates comparative phylogeography, urban landscape genetics, macrogenetics and a systemat...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Genes |
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| Online Access: | https://www.mdpi.com/2073-4425/14/7/1442 |
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| author | Chrystian C. Sosa Catalina Arenas Víctor Hugo García-Merchán |
| author_facet | Chrystian C. Sosa Catalina Arenas Víctor Hugo García-Merchán |
| author_sort | Chrystian C. Sosa |
| collection | DOAJ |
| description | On a planet experiencing constant human population growth, it is necessary to explore the anthropogenic effects on the genetic diversity of species, and specifically invasive species. Using an analysis that integrates comparative phylogeography, urban landscape genetics, macrogenetics and a systematic review, we explore the worldwide genetic diversity of the human commensal and anthropogenic species <i>Rattus rattus</i> and <i>Rattus norvegicus</i>. Based on metadata obtained considering 35 selected studies related to observed heterozygosity, measured by nuclear molecular markers (microsatellites, Single Nucleotide Polymorphisms—SNPs-, restrictition site-associated DNA sequencing -RAD-Seq-), socioeconomic and mobility anthropogenic factors were used as predictors of genetic diversity of <i>R. rattus</i> and <i>R. norvegicus</i>, using the Gini index, principal component analysis and Random Forest Regression as analysis methodology. Population density was on average the best predictor of genetic diversity in the <i>Rattus</i> species analyzed, indicating that the species respond in a particular way to the characteristics present in urban environments because of a combination of life history characteristics and human-mediated migration and colonization processes. To create better management and control strategies for these rodents and their associated diseases, it is necessary to fill the existing information gap in urban landscape genetics studies with more metadata repositories, with emphasis on tropical and subtropical regions of the world. |
| first_indexed | 2024-03-11T01:02:40Z |
| format | Article |
| id | doaj.art-6bd3e002cbac4c3b8942efb98a00ad20 |
| institution | Directory Open Access Journal |
| issn | 2073-4425 |
| language | English |
| last_indexed | 2024-03-11T01:02:40Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Genes |
| spelling | doaj.art-6bd3e002cbac4c3b8942efb98a00ad202023-11-18T19:30:32ZengMDPI AGGenes2073-44252023-07-01147144210.3390/genes14071442Human Population Density Influences Genetic Diversity of Two <i>Rattus</i> Species Worldwide: A Macrogenetic ApproachChrystian C. Sosa0Catalina Arenas1Víctor Hugo García-Merchán2Evolution, Ecology and Conservation Research Group—EECO, Biology Program, Faculty of Basic Sciences and Technologies, Universidad del Quindío, Armenia 630004, ColombiaEvolution, Ecology and Conservation Research Group—EECO, Biology Program, Faculty of Basic Sciences and Technologies, Universidad del Quindío, Armenia 630004, ColombiaEvolution, Ecology and Conservation Research Group—EECO, Biology Program, Faculty of Basic Sciences and Technologies, Universidad del Quindío, Armenia 630004, ColombiaOn a planet experiencing constant human population growth, it is necessary to explore the anthropogenic effects on the genetic diversity of species, and specifically invasive species. Using an analysis that integrates comparative phylogeography, urban landscape genetics, macrogenetics and a systematic review, we explore the worldwide genetic diversity of the human commensal and anthropogenic species <i>Rattus rattus</i> and <i>Rattus norvegicus</i>. Based on metadata obtained considering 35 selected studies related to observed heterozygosity, measured by nuclear molecular markers (microsatellites, Single Nucleotide Polymorphisms—SNPs-, restrictition site-associated DNA sequencing -RAD-Seq-), socioeconomic and mobility anthropogenic factors were used as predictors of genetic diversity of <i>R. rattus</i> and <i>R. norvegicus</i>, using the Gini index, principal component analysis and Random Forest Regression as analysis methodology. Population density was on average the best predictor of genetic diversity in the <i>Rattus</i> species analyzed, indicating that the species respond in a particular way to the characteristics present in urban environments because of a combination of life history characteristics and human-mediated migration and colonization processes. To create better management and control strategies for these rodents and their associated diseases, it is necessary to fill the existing information gap in urban landscape genetics studies with more metadata repositories, with emphasis on tropical and subtropical regions of the world.https://www.mdpi.com/2073-4425/14/7/1442invasive speciessystematic reviewurban landscape geneticsmetadatacomparative phylogeography |
| spellingShingle | Chrystian C. Sosa Catalina Arenas Víctor Hugo García-Merchán Human Population Density Influences Genetic Diversity of Two <i>Rattus</i> Species Worldwide: A Macrogenetic Approach Genes invasive species systematic review urban landscape genetics metadata comparative phylogeography |
| title | Human Population Density Influences Genetic Diversity of Two <i>Rattus</i> Species Worldwide: A Macrogenetic Approach |
| title_full | Human Population Density Influences Genetic Diversity of Two <i>Rattus</i> Species Worldwide: A Macrogenetic Approach |
| title_fullStr | Human Population Density Influences Genetic Diversity of Two <i>Rattus</i> Species Worldwide: A Macrogenetic Approach |
| title_full_unstemmed | Human Population Density Influences Genetic Diversity of Two <i>Rattus</i> Species Worldwide: A Macrogenetic Approach |
| title_short | Human Population Density Influences Genetic Diversity of Two <i>Rattus</i> Species Worldwide: A Macrogenetic Approach |
| title_sort | human population density influences genetic diversity of two i rattus i species worldwide a macrogenetic approach |
| topic | invasive species systematic review urban landscape genetics metadata comparative phylogeography |
| url | https://www.mdpi.com/2073-4425/14/7/1442 |
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