Downregulation of MMP-2 and MMP-9 genes in obesity patients and their relation with obesity-related phenotypes

Downregulation of MMP-2 and MMP-9 genes in obesity patients and their relation with obesity-related phenotypes

Adipose tissue mediates various bioactive molecules and cytokine discharge. The anti-inflammatory cytokine, interleukin-10 (IL-10), has roles in systemic inflammation. Matrix metalloproteinases (MMPs) are endopeptidases implicating in tissue remodeling, and extracellular matrix degradation. Interleu...

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Bibliographic Details
Main Authors: Aksoyer Sezgin Saadet Busra, Bayoglu Burcu, Ersoz Feyzullah, Sarici Murat, Niyazoglu Mutlu, Dirican Ahmet, Cengiz Müjgan
Format: Article
Language:English
Published: De Gruyter 2022-05-01
Series:Türk Biyokimya Dergisi
Subjects:
adipose tissue
interleukin-10
mmp-2
mmp-9
mrna levels
obesity
Online Access:https://doi.org/10.1515/tjb-2021-0124

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