Bone densitometry by dual‐energy X‐ray absorptiometry (DXA) in preterm newborns compared with full‐term peers in the first six months of life
Objectives: To longitudinally assess bone mineral content (BMC), bone mineral density (BMD), and whole‐body lean mass obtained through bone densitometry by dual‐energy X‐ray absorptiometry (DXA) in preterm newborns (PTNs) and compare them with full‐term newborns (FTNs) from birth to 6 months of corr...
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| Format: | Article |
| Language: | Portuguese |
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Brazilian Society of Pediatrics
2014-11-01
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| Series: | Jornal de Pediatria (Versão em Português) |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2255553614001177 |
| _version_ | 1811248747182555136 |
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| author | Virginia S. Quintal Edna M.A. Diniz Valeria de F. Caparbo Rosa M.R. Pereira |
| author_facet | Virginia S. Quintal Edna M.A. Diniz Valeria de F. Caparbo Rosa M.R. Pereira |
| author_sort | Virginia S. Quintal |
| collection | DOAJ |
| description | Objectives: To longitudinally assess bone mineral content (BMC), bone mineral density (BMD), and whole‐body lean mass obtained through bone densitometry by dual‐energy X‐ray absorptiometry (DXA) in preterm newborns (PTNs) and compare them with full‐term newborns (FTNs) from birth to 6 months of corrected postnatal age.
Methods: A total of 28 adequate for gestational age (AGA) newborns were studied: 14 preterm and 14 full‐term newborns. DXA was used to determine BMC, BMD, and lean mass in three moments: 40 weeks corrected post‐conceptual age, as well as 3 and 6 months of corrected postnatal age. PTNs had gestational age ≤ 32 weeks at birth and were fed their mother's own milk or milk from the human milk bank.
Results: All infants had an increase in BMC, BMD, and lean body mass values during the study. PTNs had lower BMC, BMD, and lean mass at 40 weeks of corrected post‐conceptual age in relation to FTNs (p < 0.001, p < 0.001, p = 0.047, respectively). However, there was an acceleration in the mineralization process of PTNs, which was sufficient to achieve the normal values of FTNs at 6 months of corrected age.
Conclusions: This study suggests that bone densitometry by dual‐energy X‐ray absorptiometry is a good method for the assessment of body composition parameters at baseline, and at the follow‐up of these PTNs. |
| first_indexed | 2024-04-12T15:34:39Z |
| format | Article |
| id | doaj.art-6bd9418f5f0745a18261892953add335 |
| institution | Directory Open Access Journal |
| issn | 2255-5536 |
| language | Portuguese |
| last_indexed | 2024-04-12T15:34:39Z |
| publishDate | 2014-11-01 |
| publisher | Brazilian Society of Pediatrics |
| record_format | Article |
| series | Jornal de Pediatria (Versão em Português) |
| spelling | doaj.art-6bd9418f5f0745a18261892953add3352022-12-22T03:27:00ZporBrazilian Society of PediatricsJornal de Pediatria (Versão em Português)2255-55362014-11-0190655656210.1016/j.jpedp.2014.03.002Bone densitometry by dual‐energy X‐ray absorptiometry (DXA) in preterm newborns compared with full‐term peers in the first six months of lifeVirginia S. Quintal0Edna M.A. Diniz1Valeria de F. Caparbo2Rosa M.R. Pereira3Banco de Leite Humano, Hospital Universitário, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, BrasilDepartamento de Pediatria, Hospital Universitário, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, BrasilDivisão de Reumatologia, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, BrasilDivisão de Reumatologia, Faculdade de Medicina, Universidade de São Paulo (USP), São Paulo, SP, BrasilObjectives: To longitudinally assess bone mineral content (BMC), bone mineral density (BMD), and whole‐body lean mass obtained through bone densitometry by dual‐energy X‐ray absorptiometry (DXA) in preterm newborns (PTNs) and compare them with full‐term newborns (FTNs) from birth to 6 months of corrected postnatal age. Methods: A total of 28 adequate for gestational age (AGA) newborns were studied: 14 preterm and 14 full‐term newborns. DXA was used to determine BMC, BMD, and lean mass in three moments: 40 weeks corrected post‐conceptual age, as well as 3 and 6 months of corrected postnatal age. PTNs had gestational age ≤ 32 weeks at birth and were fed their mother's own milk or milk from the human milk bank. Results: All infants had an increase in BMC, BMD, and lean body mass values during the study. PTNs had lower BMC, BMD, and lean mass at 40 weeks of corrected post‐conceptual age in relation to FTNs (p < 0.001, p < 0.001, p = 0.047, respectively). However, there was an acceleration in the mineralization process of PTNs, which was sufficient to achieve the normal values of FTNs at 6 months of corrected age. Conclusions: This study suggests that bone densitometry by dual‐energy X‐ray absorptiometry is a good method for the assessment of body composition parameters at baseline, and at the follow‐up of these PTNs.http://www.sciencedirect.com/science/article/pii/S2255553614001177PrematurityNewbornBone mineralizationDensitometryHuman milk |
| spellingShingle | Virginia S. Quintal Edna M.A. Diniz Valeria de F. Caparbo Rosa M.R. Pereira Bone densitometry by dual‐energy X‐ray absorptiometry (DXA) in preterm newborns compared with full‐term peers in the first six months of life Jornal de Pediatria (Versão em Português) Prematurity Newborn Bone mineralization Densitometry Human milk |
| title | Bone densitometry by dual‐energy X‐ray absorptiometry (DXA) in preterm newborns compared with full‐term peers in the first six months of life |
| title_full | Bone densitometry by dual‐energy X‐ray absorptiometry (DXA) in preterm newborns compared with full‐term peers in the first six months of life |
| title_fullStr | Bone densitometry by dual‐energy X‐ray absorptiometry (DXA) in preterm newborns compared with full‐term peers in the first six months of life |
| title_full_unstemmed | Bone densitometry by dual‐energy X‐ray absorptiometry (DXA) in preterm newborns compared with full‐term peers in the first six months of life |
| title_short | Bone densitometry by dual‐energy X‐ray absorptiometry (DXA) in preterm newborns compared with full‐term peers in the first six months of life |
| title_sort | bone densitometry by dual energy x ray absorptiometry dxa in preterm newborns compared with full term peers in the first six months of life |
| topic | Prematurity Newborn Bone mineralization Densitometry Human milk |
| url | http://www.sciencedirect.com/science/article/pii/S2255553614001177 |
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