Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration

Bioresorbable electronic stimulators can deliver electrical stimulation in rodents to enhance functional muscle recovery after nerve injury. Here, the authors present a bioresorbable dynamic covalent polymer that enables reliable, long-lived operation of soft, stretchable devices of this type.

Bibliographic Details
Main Authors: Yeon Sik Choi, Yuan-Yu Hsueh, Jahyun Koo, Quansan Yang, Raudel Avila, Buwei Hu, Zhaoqian Xie, Geumbee Lee, Zheng Ning, Claire Liu, Yameng Xu, Young Joong Lee, Weikang Zhao, Jun Fang, Yujun Deng, Seung Min Lee, Abraham Vázquez-Guardado, Iwona Stepien, Ying Yan, Joseph W. Song, Chad Haney, Yong Suk Oh, Wentai Liu, Hong-Joon Yoon, Anthony Banks, Matthew R. MacEwan, Guillermo A. Ameer, Wilson Z. Ray, Yonggang Huang, Tao Xie, Colin K. Franz, Song Li, John A. Rogers
Format: Article
Language:English
Published: Nature Portfolio 2020-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-19660-6
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author Yeon Sik Choi
Yuan-Yu Hsueh
Jahyun Koo
Quansan Yang
Raudel Avila
Buwei Hu
Zhaoqian Xie
Geumbee Lee
Zheng Ning
Claire Liu
Yameng Xu
Young Joong Lee
Weikang Zhao
Jun Fang
Yujun Deng
Seung Min Lee
Abraham Vázquez-Guardado
Iwona Stepien
Ying Yan
Joseph W. Song
Chad Haney
Yong Suk Oh
Wentai Liu
Hong-Joon Yoon
Anthony Banks
Matthew R. MacEwan
Guillermo A. Ameer
Wilson Z. Ray
Yonggang Huang
Tao Xie
Colin K. Franz
Song Li
John A. Rogers
author_facet Yeon Sik Choi
Yuan-Yu Hsueh
Jahyun Koo
Quansan Yang
Raudel Avila
Buwei Hu
Zhaoqian Xie
Geumbee Lee
Zheng Ning
Claire Liu
Yameng Xu
Young Joong Lee
Weikang Zhao
Jun Fang
Yujun Deng
Seung Min Lee
Abraham Vázquez-Guardado
Iwona Stepien
Ying Yan
Joseph W. Song
Chad Haney
Yong Suk Oh
Wentai Liu
Hong-Joon Yoon
Anthony Banks
Matthew R. MacEwan
Guillermo A. Ameer
Wilson Z. Ray
Yonggang Huang
Tao Xie
Colin K. Franz
Song Li
John A. Rogers
author_sort Yeon Sik Choi
collection DOAJ
description Bioresorbable electronic stimulators can deliver electrical stimulation in rodents to enhance functional muscle recovery after nerve injury. Here, the authors present a bioresorbable dynamic covalent polymer that enables reliable, long-lived operation of soft, stretchable devices of this type.
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spelling doaj.art-6bde3ba97d03446bb70cdf4014e893242022-12-21T21:21:38ZengNature PortfolioNature Communications2041-17232020-11-0111111410.1038/s41467-020-19660-6Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regenerationYeon Sik Choi0Yuan-Yu Hsueh1Jahyun Koo2Quansan Yang3Raudel Avila4Buwei Hu5Zhaoqian Xie6Geumbee Lee7Zheng Ning8Claire Liu9Yameng Xu10Young Joong Lee11Weikang Zhao12Jun Fang13Yujun Deng14Seung Min Lee15Abraham Vázquez-Guardado16Iwona Stepien17Ying Yan18Joseph W. Song19Chad Haney20Yong Suk Oh21Wentai Liu22Hong-Joon Yoon23Anthony Banks24Matthew R. MacEwan25Guillermo A. Ameer26Wilson Z. Ray27Yonggang Huang28Tao Xie29Colin K. Franz30Song Li31John A. Rogers32Center for Bio-Integrated Electronics, Northwestern UniversityDepartment of Bioengineering, University of California, Los AngelesCenter for Bio-Integrated Electronics, Northwestern UniversityQuerrey Simpson Institute for Biotechnology, Northwestern UniversityDepartment of Mechanical Engineering, Northwestern UniversityDepartment of Bioengineering, University of California, Los AngelesState Key Laboratory of Structural Analysis for Industrial Equipment, Dalian, University of TechnologyCenter for Bio-Integrated Electronics, Northwestern UniversityState Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang UniversityQuerrey Simpson Institute for Biotechnology, Northwestern UniversityQuerrey Simpson Institute for Biotechnology, Northwestern UniversityQuerrey Simpson Institute for Biotechnology, Northwestern UniversityDepartment of Bioengineering, University of California, Los AngelesDepartment of Bioengineering, University of California, Los AngelesDepartment of Mechanical Engineering, Northwestern UniversityCenter for Bio-Integrated Electronics, Northwestern UniversityCenter for Bio-Integrated Electronics, Northwestern UniversityCenter for Developmental Therapeutics, Chemistry Life Processes Institute, Northwestern UniversityDepartment of Neurological Surgery, Washington University School of MedicineDepartment of Biomedical Engineering, Northwestern UniversityCenter for Advanced Molecular Imaging, Northwestern UniversityCenter for Bio-Integrated Electronics, Northwestern UniversityDepartment of Bioengineering, University of California, Los AngelesQuerrey Simpson Institute for Biotechnology, Northwestern UniversityCenter for Bio-Integrated Electronics, Northwestern UniversityDepartment of Neurological Surgery, Washington University School of MedicineDepartment of Biomedical Engineering, Northwestern UniversityDepartment of Neurological Surgery, Washington University School of MedicineCenter for Bio-Integrated Electronics, Northwestern UniversityState Key Laboratory of Chemical Engineering, College of Chemical and Biological Engineering, Zhejiang UniversityRegenerative Neurorehabilitation Laboratory, Biologics, Shirley Ryan AbilityLabDepartment of Bioengineering, University of California, Los AngelesCenter for Bio-Integrated Electronics, Northwestern UniversityBioresorbable electronic stimulators can deliver electrical stimulation in rodents to enhance functional muscle recovery after nerve injury. Here, the authors present a bioresorbable dynamic covalent polymer that enables reliable, long-lived operation of soft, stretchable devices of this type.https://doi.org/10.1038/s41467-020-19660-6
spellingShingle Yeon Sik Choi
Yuan-Yu Hsueh
Jahyun Koo
Quansan Yang
Raudel Avila
Buwei Hu
Zhaoqian Xie
Geumbee Lee
Zheng Ning
Claire Liu
Yameng Xu
Young Joong Lee
Weikang Zhao
Jun Fang
Yujun Deng
Seung Min Lee
Abraham Vázquez-Guardado
Iwona Stepien
Ying Yan
Joseph W. Song
Chad Haney
Yong Suk Oh
Wentai Liu
Hong-Joon Yoon
Anthony Banks
Matthew R. MacEwan
Guillermo A. Ameer
Wilson Z. Ray
Yonggang Huang
Tao Xie
Colin K. Franz
Song Li
John A. Rogers
Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration
Nature Communications
title Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration
title_full Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration
title_fullStr Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration
title_full_unstemmed Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration
title_short Stretchable, dynamic covalent polymers for soft, long-lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration
title_sort stretchable dynamic covalent polymers for soft long lived bioresorbable electronic stimulators designed to facilitate neuromuscular regeneration
url https://doi.org/10.1038/s41467-020-19660-6
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