Evaluation of phenolic profile, antioxidant and anticholinesterase effects of Fuscoporia torulosa
In this study, we investigated antioxidant and anticholinesterase activities of the hexane, chloroform, acetone, methanol and water extracts of F. torulosa mushroom with total phenolic contents. Also, HPLC-DAD was used to identify phenolic profile of F. torulosa. The acetone and methanol extracts of...
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| Format: | Article |
| Language: | English |
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International Journal of Secondary Metabolite
2019-03-01
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| Series: | International Journal of Secondary Metabolite |
| Subjects: | |
| Online Access: | https://dergipark.org.tr/tr/pub/ijsm/issue/41604/496327?publisher=ijate |
| _version_ | 1797917929449193472 |
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| author | Mehmet Emin Emin Duru Gülsen Tel-Çayan Ebru Deveci |
| author_facet | Mehmet Emin Emin Duru Gülsen Tel-Çayan Ebru Deveci |
| author_sort | Mehmet Emin Emin Duru |
| collection | DOAJ |
| description | In this study, we investigated antioxidant and anticholinesterase activities of the hexane, chloroform, acetone, methanol and water extracts of F. torulosa mushroom with total phenolic contents. Also, HPLC-DAD was used to identify phenolic profile of F. torulosa. The acetone and methanol extracts of F. torulosa with the highest total phenolic contents showed the highest antioxidant activity in all assays except metal chelating assay. Furthermore, antioxidant activities of the acetone and methanol extract were found to be higher than α-tocopherol and BHA used as standards in DPPH•, ABTS•+ and CUPRAC assays. When F. torulosa hexane extract (41.34±1.50 %) showed moderate AChE inhibitory activity, the acetone (40.78±0.30 %) and methanol (45.39±0.65 %) extracts of F. torulosa indicated moderate BChE inhibitory activity. Major phenolic compounds were identified as trans-2-hydroxy cinnamic acid (10.05 µg/g), gallic acid (5.01 µg/g) and p-coumaric acid (3.04 µg/g). These results suggest that F. torulosa mushroom could be used as a valuable natural antioxidant source for pharmaceutical industry. |
| first_indexed | 2024-04-10T13:21:23Z |
| format | Article |
| id | doaj.art-6be0221bb6fd4ebe868518ea71fa9cd5 |
| institution | Directory Open Access Journal |
| issn | 2148-6905 |
| language | English |
| last_indexed | 2024-04-10T13:21:23Z |
| publishDate | 2019-03-01 |
| publisher | International Journal of Secondary Metabolite |
| record_format | Article |
| series | International Journal of Secondary Metabolite |
| spelling | doaj.art-6be0221bb6fd4ebe868518ea71fa9cd52023-02-15T16:12:02ZengInternational Journal of Secondary MetaboliteInternational Journal of Secondary Metabolite2148-69052019-03-0161798910.21448/ijsm.496327618Evaluation of phenolic profile, antioxidant and anticholinesterase effects of Fuscoporia torulosaMehmet Emin Emin Duru0Gülsen Tel-Çayan1Ebru Deveci2MUĞLA SITKI KOÇMAN ÜNİVERSİTESİMUĞLA SITKI KOÇMAN ÜNİVERSİTESİMUĞLA SITKI KOÇMAN ÜNİVERSİTESİIn this study, we investigated antioxidant and anticholinesterase activities of the hexane, chloroform, acetone, methanol and water extracts of F. torulosa mushroom with total phenolic contents. Also, HPLC-DAD was used to identify phenolic profile of F. torulosa. The acetone and methanol extracts of F. torulosa with the highest total phenolic contents showed the highest antioxidant activity in all assays except metal chelating assay. Furthermore, antioxidant activities of the acetone and methanol extract were found to be higher than α-tocopherol and BHA used as standards in DPPH•, ABTS•+ and CUPRAC assays. When F. torulosa hexane extract (41.34±1.50 %) showed moderate AChE inhibitory activity, the acetone (40.78±0.30 %) and methanol (45.39±0.65 %) extracts of F. torulosa indicated moderate BChE inhibitory activity. Major phenolic compounds were identified as trans-2-hydroxy cinnamic acid (10.05 µg/g), gallic acid (5.01 µg/g) and p-coumaric acid (3.04 µg/g). These results suggest that F. torulosa mushroom could be used as a valuable natural antioxidant source for pharmaceutical industry.https://dergipark.org.tr/tr/pub/ijsm/issue/41604/496327?publisher=ijatefuscoporia torulosaphenolic profilehplc-dadantioxidant activityanticholinesterase activity |
| spellingShingle | Mehmet Emin Emin Duru Gülsen Tel-Çayan Ebru Deveci Evaluation of phenolic profile, antioxidant and anticholinesterase effects of Fuscoporia torulosa International Journal of Secondary Metabolite fuscoporia torulosa phenolic profile hplc-dad antioxidant activity anticholinesterase activity |
| title | Evaluation of phenolic profile, antioxidant and anticholinesterase effects of Fuscoporia torulosa |
| title_full | Evaluation of phenolic profile, antioxidant and anticholinesterase effects of Fuscoporia torulosa |
| title_fullStr | Evaluation of phenolic profile, antioxidant and anticholinesterase effects of Fuscoporia torulosa |
| title_full_unstemmed | Evaluation of phenolic profile, antioxidant and anticholinesterase effects of Fuscoporia torulosa |
| title_short | Evaluation of phenolic profile, antioxidant and anticholinesterase effects of Fuscoporia torulosa |
| title_sort | evaluation of phenolic profile antioxidant and anticholinesterase effects of fuscoporia torulosa |
| topic | fuscoporia torulosa phenolic profile hplc-dad antioxidant activity anticholinesterase activity |
| url | https://dergipark.org.tr/tr/pub/ijsm/issue/41604/496327?publisher=ijate |
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