Orbital lesion (pseudotumor and dacryoadenitis) is a manifestation of systemic sarcoidosis

<p> <b>E.A.&nbsp;Burylova, L.A.&nbsp;Mamaeva, A.S.&nbsp;Berdnikova, O.K.&nbsp;Fedorova</b> </p> <p> <b>Ural Scientific Research Institute of Phtysiopulmonology — Branch of the National Medical Research Center of Phtysiopulmonology, Yekaterinburg,...

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Main Authors: E.A. Burylova, L.A. Mamaeva, A.S. Berdnikova, O.K. Fedorova
Format: Article
Language:Russian
Published: Prime-Media 2021-03-01
Series:РМЖ "Клиническая офтальмология"
Online Access:http://clinopht.com/upload/iblock/ea9/ea94c57db25c2a4e6c7aef540270d16e.pdf
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author E.A. Burylova
L.A. Mamaeva
A.S. Berdnikova
O.K. Fedorova
author_facet E.A. Burylova
L.A. Mamaeva
A.S. Berdnikova
O.K. Fedorova
author_sort E.A. Burylova
collection DOAJ
description <p> <b>E.A.&nbsp;Burylova, L.A.&nbsp;Mamaeva, A.S.&nbsp;Berdnikova, O.K.&nbsp;Fedorova</b> </p> <p> <b>Ural Scientific Research Institute of Phtysiopulmonology — Branch of the National Medical Research Center of Phtysiopulmonology, Yekaterinburg, Russian Federation</b> </p> <p> <b>Abstract</b> </p> <p> <i>Ocular manifestations of systemic sarcoidosis may emerge at any disease stage. Ocular sarcoidosis is typically characterized by uveitic presentations that predominantly involve the choroid of anterior eye segment. However, orbital pseudotumor, dacryoadenitis, and other rare presentations (optic neuritis, dacryocystitis etc.) also occur in sarcoidosis. Threatened vision loss and poor quality of life are the reasons to prescribe systemic steroids in generalized sarcoidosis. Chest CT is required to identify respiratory diseases when sarcoidosis manifests as uveitis or granulomatous orbital inflammation. Multidisciplinary diagnostic and treatment approach to suspected sarcoidosis provides timely verified diagnosis and management strategy. This paper addresses case report of systemic sarcoidosis in a 34-year-old man. The initial manifestation was vision loss and left orbital pseudotumor. The enlarged subclavian lymph node and its biopsy were suspicious of granulomatous inflammation. Chest CT identified disseminated pulmonary lesions and intrathoracic lymphadenopathy that are typical of sarcoidosis. The results of multidisciplinary examina tions verified systemic sarcoidosis. Systemic steroids resulted in clinical and radiological improvement and medicinal regression of the disease.</i> </p> <p> <i><b>Keywords</b>: sarcoidosis, orbital pseudotumor, dacryoadenitis, adenopathy, computed tomography, multidisciplinary approach.</i> </p> <p> <i><b>For citation: </b>Burylova E.A., Mamaeva L.A., Berdnikova A.S., Fedorova O.K. Orbital lesion (pseudotumor and dacryoadenitis) is a manifestation of systemic sarcoidosis. Russian Journal of Clinical Ophthalmology. 2021;21(1):40–44. DOI: 10.32364/2311-7729-2021-21-1-40-44.</i> </p> <i><br> </i><br>
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spelling doaj.art-6be03d781d8e4a648058be73552648802024-02-26T10:12:09ZrusPrime-MediaРМЖ "Клиническая офтальмология"2311-77292619-15712021-03-0121131263Orbital lesion (pseudotumor and dacryoadenitis) is a manifestation of systemic sarcoidosisE.A. Burylova0L.A. Mamaeva1A.S. Berdnikova2O.K. Fedorova3Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399Russian Journal of Clinical Ophthalmology, Publisher of «Medicina-Inform» Address for correspondence: Russia, 105064, Moscow, P.O. Box 399<p> <b>E.A.&nbsp;Burylova, L.A.&nbsp;Mamaeva, A.S.&nbsp;Berdnikova, O.K.&nbsp;Fedorova</b> </p> <p> <b>Ural Scientific Research Institute of Phtysiopulmonology — Branch of the National Medical Research Center of Phtysiopulmonology, Yekaterinburg, Russian Federation</b> </p> <p> <b>Abstract</b> </p> <p> <i>Ocular manifestations of systemic sarcoidosis may emerge at any disease stage. Ocular sarcoidosis is typically characterized by uveitic presentations that predominantly involve the choroid of anterior eye segment. However, orbital pseudotumor, dacryoadenitis, and other rare presentations (optic neuritis, dacryocystitis etc.) also occur in sarcoidosis. Threatened vision loss and poor quality of life are the reasons to prescribe systemic steroids in generalized sarcoidosis. Chest CT is required to identify respiratory diseases when sarcoidosis manifests as uveitis or granulomatous orbital inflammation. Multidisciplinary diagnostic and treatment approach to suspected sarcoidosis provides timely verified diagnosis and management strategy. This paper addresses case report of systemic sarcoidosis in a 34-year-old man. The initial manifestation was vision loss and left orbital pseudotumor. The enlarged subclavian lymph node and its biopsy were suspicious of granulomatous inflammation. Chest CT identified disseminated pulmonary lesions and intrathoracic lymphadenopathy that are typical of sarcoidosis. The results of multidisciplinary examina tions verified systemic sarcoidosis. Systemic steroids resulted in clinical and radiological improvement and medicinal regression of the disease.</i> </p> <p> <i><b>Keywords</b>: sarcoidosis, orbital pseudotumor, dacryoadenitis, adenopathy, computed tomography, multidisciplinary approach.</i> </p> <p> <i><b>For citation: </b>Burylova E.A., Mamaeva L.A., Berdnikova A.S., Fedorova O.K. Orbital lesion (pseudotumor and dacryoadenitis) is a manifestation of systemic sarcoidosis. Russian Journal of Clinical Ophthalmology. 2021;21(1):40–44. DOI: 10.32364/2311-7729-2021-21-1-40-44.</i> </p> <i><br> </i><br>http://clinopht.com/upload/iblock/ea9/ea94c57db25c2a4e6c7aef540270d16e.pdf
spellingShingle E.A. Burylova
L.A. Mamaeva
A.S. Berdnikova
O.K. Fedorova
Orbital lesion (pseudotumor and dacryoadenitis) is a manifestation of systemic sarcoidosis
РМЖ "Клиническая офтальмология"
title Orbital lesion (pseudotumor and dacryoadenitis) is a manifestation of systemic sarcoidosis
title_full Orbital lesion (pseudotumor and dacryoadenitis) is a manifestation of systemic sarcoidosis
title_fullStr Orbital lesion (pseudotumor and dacryoadenitis) is a manifestation of systemic sarcoidosis
title_full_unstemmed Orbital lesion (pseudotumor and dacryoadenitis) is a manifestation of systemic sarcoidosis
title_short Orbital lesion (pseudotumor and dacryoadenitis) is a manifestation of systemic sarcoidosis
title_sort orbital lesion pseudotumor and dacryoadenitis is a manifestation of systemic sarcoidosis
url http://clinopht.com/upload/iblock/ea9/ea94c57db25c2a4e6c7aef540270d16e.pdf
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AT okfedorova orbitallesionpseudotumoranddacryoadenitisisamanifestationofsystemicsarcoidosis