Does air pollution exposure affect semen quality? Evidence from a systematic review and meta-analysis of 93,996 Chinese men
BackgroundAir pollution may impair male fertility, but it remains controversial whether air pollution affects semen quality until now.ObjectivesWe undertake a meta-analysis to explore potential impacts of six pollutants exposure during the entire window (0–90 days prior to ejaculation) and critical...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-08-01
|
| Series: | Frontiers in Public Health |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1219340/full |
| _version_ | 1797755154449039360 |
|---|---|
| author | Junjie Liu Yanpeng Dai Runqing Li Jiayi Yuan Quanxian Wang Linkai Wang |
| author_facet | Junjie Liu Yanpeng Dai Runqing Li Jiayi Yuan Quanxian Wang Linkai Wang |
| author_sort | Junjie Liu |
| collection | DOAJ |
| description | BackgroundAir pollution may impair male fertility, but it remains controversial whether air pollution affects semen quality until now.ObjectivesWe undertake a meta-analysis to explore potential impacts of six pollutants exposure during the entire window (0–90 days prior to ejaculation) and critical windows (0–9, 10–14, and 70–90 days prior to ejaculation) on semen quality.MethodsSeven databases were retrieved for original studies on the effects of six pollutants exposure for 90 days prior to ejaculation on semen quality. The search process does not limit the language and search date. We only included original studies that reported regression coefficients (β) with 95% confidence intervals (CIs). The β and 95% CIs were pooled using the DerSimonian-Laird random effect models.ResultsPM2.5 exposure was related with decreased total sperm number (10–14 lag days) and total motility (10–14, 70–90, and 0–90 lag days). PM10 exposure was related with reduced total sperm number (70–90 and 0–90 lag days) and total motility (0–90 lag days). NO2 exposure was related with reduced total sperm number (70–90 and 0–90 lag days). SO2 exposure was related with declined total motility (0–9, 10–14, 0–90 lag days) and total sperm number (0–90 lag days).ConclusionAir pollution affects semen quality making it necessary to limit exposure to air pollution for Chinese men. When implementing protective measures, it is necessary to consider the key period of sperm development. |
| first_indexed | 2024-03-12T17:43:41Z |
| format | Article |
| id | doaj.art-6be047e686e14a1dbd9fef29b3b8cd8a |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-03-12T17:43:41Z |
| publishDate | 2023-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-6be047e686e14a1dbd9fef29b3b8cd8a2023-08-03T23:11:52ZengFrontiers Media S.A.Frontiers in Public Health2296-25652023-08-011110.3389/fpubh.2023.12193401219340Does air pollution exposure affect semen quality? Evidence from a systematic review and meta-analysis of 93,996 Chinese menJunjie Liu0Yanpeng Dai1Runqing Li2Jiayi Yuan3Quanxian Wang4Linkai Wang5Henan Human Sperm Bank, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaDepartment of Clinical Laboratory, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaThe Neonatal Screening Center in Henan Province, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaThe Neonatal Screening Center in Henan Province, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaHenan Human Sperm Bank, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaHenan Human Sperm Bank, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, ChinaBackgroundAir pollution may impair male fertility, but it remains controversial whether air pollution affects semen quality until now.ObjectivesWe undertake a meta-analysis to explore potential impacts of six pollutants exposure during the entire window (0–90 days prior to ejaculation) and critical windows (0–9, 10–14, and 70–90 days prior to ejaculation) on semen quality.MethodsSeven databases were retrieved for original studies on the effects of six pollutants exposure for 90 days prior to ejaculation on semen quality. The search process does not limit the language and search date. We only included original studies that reported regression coefficients (β) with 95% confidence intervals (CIs). The β and 95% CIs were pooled using the DerSimonian-Laird random effect models.ResultsPM2.5 exposure was related with decreased total sperm number (10–14 lag days) and total motility (10–14, 70–90, and 0–90 lag days). PM10 exposure was related with reduced total sperm number (70–90 and 0–90 lag days) and total motility (0–90 lag days). NO2 exposure was related with reduced total sperm number (70–90 and 0–90 lag days). SO2 exposure was related with declined total motility (0–9, 10–14, 0–90 lag days) and total sperm number (0–90 lag days).ConclusionAir pollution affects semen quality making it necessary to limit exposure to air pollution for Chinese men. When implementing protective measures, it is necessary to consider the key period of sperm development.https://www.frontiersin.org/articles/10.3389/fpubh.2023.1219340/fullsemen analysisair pollutionparticulate mattermeta-analysissystematic review |
| spellingShingle | Junjie Liu Yanpeng Dai Runqing Li Jiayi Yuan Quanxian Wang Linkai Wang Does air pollution exposure affect semen quality? Evidence from a systematic review and meta-analysis of 93,996 Chinese men Frontiers in Public Health semen analysis air pollution particulate matter meta-analysis systematic review |
| title | Does air pollution exposure affect semen quality? Evidence from a systematic review and meta-analysis of 93,996 Chinese men |
| title_full | Does air pollution exposure affect semen quality? Evidence from a systematic review and meta-analysis of 93,996 Chinese men |
| title_fullStr | Does air pollution exposure affect semen quality? Evidence from a systematic review and meta-analysis of 93,996 Chinese men |
| title_full_unstemmed | Does air pollution exposure affect semen quality? Evidence from a systematic review and meta-analysis of 93,996 Chinese men |
| title_short | Does air pollution exposure affect semen quality? Evidence from a systematic review and meta-analysis of 93,996 Chinese men |
| title_sort | does air pollution exposure affect semen quality evidence from a systematic review and meta analysis of 93 996 chinese men |
| topic | semen analysis air pollution particulate matter meta-analysis systematic review |
| url | https://www.frontiersin.org/articles/10.3389/fpubh.2023.1219340/full |
| work_keys_str_mv | AT junjieliu doesairpollutionexposureaffectsemenqualityevidencefromasystematicreviewandmetaanalysisof93996chinesemen AT yanpengdai doesairpollutionexposureaffectsemenqualityevidencefromasystematicreviewandmetaanalysisof93996chinesemen AT runqingli doesairpollutionexposureaffectsemenqualityevidencefromasystematicreviewandmetaanalysisof93996chinesemen AT jiayiyuan doesairpollutionexposureaffectsemenqualityevidencefromasystematicreviewandmetaanalysisof93996chinesemen AT quanxianwang doesairpollutionexposureaffectsemenqualityevidencefromasystematicreviewandmetaanalysisof93996chinesemen AT linkaiwang doesairpollutionexposureaffectsemenqualityevidencefromasystematicreviewandmetaanalysisof93996chinesemen |