STAT3 phosphorylation at serine 727 activates specific genetic programs and promotes clear cell renal cell carcinoma (ccRCC) aggressiveness

STAT3 phosphorylation at serine 727 activates specific genetic programs and promotes clear cell renal cell carcinoma (ccRCC) aggressiveness

Abstract The signal transducer and activator of transcription 3 (STAT3) is a transcription factor mainly activated by phosphorylation in either tyrosine 705 (Y705) or serine 727 (S727) residues that regulates essential processes such as cell differentiation, apoptosis inhibition, or cell survival. A...

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Bibliographic Details
Main Authors:	J. Arévalo, I. Campoy, M. Durán, S. Nemours, A. Areny, M. Vall-Palomar, C. Martínez, G. Cantero-Recasens, A. Meseguer
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-11-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-023-46628-5

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