Fungal Endophthalmitis Outbreak after Cataract Surgery, South Korea, 2020
In November 2020, an unusual increase in fungal endophthalmitis cases after cataract surgery was reported to the Korea Disease Control and Prevention Agency, South Korea. We initiated an outbreak investigation to identify the cause. We identified 156 cases nationwide, 62 confirmed and 94 probable....
| Main Authors: | , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Centers for Disease Control and Prevention
2022-11-01
|
| Series: | Emerging Infectious Diseases |
| Subjects: | |
| Online Access: | https://wwwnc.cdc.gov/eid/article/28/11/22-0361_article |
| _version_ | 1828201750133211136 |
|---|---|
| author | Soo Jeong Yoon Soo Hyun Kim Hyun Jung Bahk Yeong Seo Ahn Ji Joo Lee Hye Jin Kim Ha Jin Lim Min Ji Choi Jong Hee Shin Yeon-Kyeng Lee |
| author_facet | Soo Jeong Yoon Soo Hyun Kim Hyun Jung Bahk Yeong Seo Ahn Ji Joo Lee Hye Jin Kim Ha Jin Lim Min Ji Choi Jong Hee Shin Yeon-Kyeng Lee |
| author_sort | Soo Jeong Yoon |
| collection | DOAJ |
| description |
In November 2020, an unusual increase in fungal endophthalmitis cases after cataract surgery was reported to the Korea Disease Control and Prevention Agency, South Korea. We initiated an outbreak investigation to identify the cause. We identified 156 cases nationwide, 62 confirmed and 94 probable. Most case-patients were exposed during surgery to ocular viscoelastic devices (OVDs) from the same manufacturer (company A). We isolated Fusarium spp. from 50 confirmed cases. Molecular identification of 39 fungal isolates from clinical samples and 13 isolates from OVDs confirmed F. oxysporum caused the infections. The risk ratio for fungal endophthalmitis from company A’s OVDs was 86.0 (95% CI 27.4–256.9), much higher than risk from other manufacturers’ products. We determined this fungal endophthalmitis outbreak was caused by a contaminated lot of OVDs and recommended discontinued use of this product. Early recognition of outbreaks and joint responses from related government agencies can reduce risk for fungal endophthalmitis.
|
| first_indexed | 2024-04-12T11:35:24Z |
| format | Article |
| id | doaj.art-6be2e0cb85f94490af135721248d0307 |
| institution | Directory Open Access Journal |
| issn | 1080-6040 1080-6059 |
| language | English |
| last_indexed | 2024-04-12T11:35:24Z |
| publishDate | 2022-11-01 |
| publisher | Centers for Disease Control and Prevention |
| record_format | Article |
| series | Emerging Infectious Diseases |
| spelling | doaj.art-6be2e0cb85f94490af135721248d03072022-12-22T03:34:51ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592022-11-0128112226223310.3201/eid2811.220361Fungal Endophthalmitis Outbreak after Cataract Surgery, South Korea, 2020Soo Jeong YoonSoo Hyun KimHyun Jung BahkYeong Seo AhnJi Joo LeeHye Jin KimHa Jin LimMin Ji ChoiJong Hee ShinYeon-Kyeng Lee In November 2020, an unusual increase in fungal endophthalmitis cases after cataract surgery was reported to the Korea Disease Control and Prevention Agency, South Korea. We initiated an outbreak investigation to identify the cause. We identified 156 cases nationwide, 62 confirmed and 94 probable. Most case-patients were exposed during surgery to ocular viscoelastic devices (OVDs) from the same manufacturer (company A). We isolated Fusarium spp. from 50 confirmed cases. Molecular identification of 39 fungal isolates from clinical samples and 13 isolates from OVDs confirmed F. oxysporum caused the infections. The risk ratio for fungal endophthalmitis from company A’s OVDs was 86.0 (95% CI 27.4–256.9), much higher than risk from other manufacturers’ products. We determined this fungal endophthalmitis outbreak was caused by a contaminated lot of OVDs and recommended discontinued use of this product. Early recognition of outbreaks and joint responses from related government agencies can reduce risk for fungal endophthalmitis. https://wwwnc.cdc.gov/eid/article/28/11/22-0361_articlefungiFusariumcataractsurgeryendophthalmitishealthcare-associated infections |
| spellingShingle | Soo Jeong Yoon Soo Hyun Kim Hyun Jung Bahk Yeong Seo Ahn Ji Joo Lee Hye Jin Kim Ha Jin Lim Min Ji Choi Jong Hee Shin Yeon-Kyeng Lee Fungal Endophthalmitis Outbreak after Cataract Surgery, South Korea, 2020 Emerging Infectious Diseases fungi Fusarium cataract surgery endophthalmitis healthcare-associated infections |
| title | Fungal Endophthalmitis Outbreak after Cataract Surgery, South Korea, 2020 |
| title_full | Fungal Endophthalmitis Outbreak after Cataract Surgery, South Korea, 2020 |
| title_fullStr | Fungal Endophthalmitis Outbreak after Cataract Surgery, South Korea, 2020 |
| title_full_unstemmed | Fungal Endophthalmitis Outbreak after Cataract Surgery, South Korea, 2020 |
| title_short | Fungal Endophthalmitis Outbreak after Cataract Surgery, South Korea, 2020 |
| title_sort | fungal endophthalmitis outbreak after cataract surgery south korea 2020 |
| topic | fungi Fusarium cataract surgery endophthalmitis healthcare-associated infections |
| url | https://wwwnc.cdc.gov/eid/article/28/11/22-0361_article |
| work_keys_str_mv | AT soojeongyoon fungalendophthalmitisoutbreakaftercataractsurgerysouthkorea2020 AT soohyunkim fungalendophthalmitisoutbreakaftercataractsurgerysouthkorea2020 AT hyunjungbahk fungalendophthalmitisoutbreakaftercataractsurgerysouthkorea2020 AT yeongseoahn fungalendophthalmitisoutbreakaftercataractsurgerysouthkorea2020 AT jijoolee fungalendophthalmitisoutbreakaftercataractsurgerysouthkorea2020 AT hyejinkim fungalendophthalmitisoutbreakaftercataractsurgerysouthkorea2020 AT hajinlim fungalendophthalmitisoutbreakaftercataractsurgerysouthkorea2020 AT minjichoi fungalendophthalmitisoutbreakaftercataractsurgerysouthkorea2020 AT jongheeshin fungalendophthalmitisoutbreakaftercataractsurgerysouthkorea2020 AT yeonkyenglee fungalendophthalmitisoutbreakaftercataractsurgerysouthkorea2020 |