Superficial siderosis of the central nervous system is a rare and possibly underdiagnosed disorder
ABSTRACT Superficial siderosis (SS) of the central nervous system (CNS) is a rare and possibly underdiagnosed disorder resulting from chronic or intermittent bleeding into the subarachnoid space, leading to deposition of blood products in the subpial layers of the meninges. Magnetic resonance imagin...
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| Format: | Article |
| Language: | English |
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Academia Brasileira de Neurologia (ABNEURO)
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| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000200004&lng=en&tlng=en |
| _version_ | 1819126700780290048 |
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| author | Yara Dadalti Fragoso Tarso Adoni Joseph Bruno Bidin Brooks Sidney Gomes Marcus Vinicius Magno Goncalves Cassio Lemos Jovem Andre Palma da Cunha Matta Joao Filipe Oliveira Fabio Siquinelli Carlos Bernardo Tauil Guilherme Navarro Troiani Paulo Roberto Wille |
| author_facet | Yara Dadalti Fragoso Tarso Adoni Joseph Bruno Bidin Brooks Sidney Gomes Marcus Vinicius Magno Goncalves Cassio Lemos Jovem Andre Palma da Cunha Matta Joao Filipe Oliveira Fabio Siquinelli Carlos Bernardo Tauil Guilherme Navarro Troiani Paulo Roberto Wille |
| author_sort | Yara Dadalti Fragoso |
| collection | DOAJ |
| description | ABSTRACT Superficial siderosis (SS) of the central nervous system (CNS) is a rare and possibly underdiagnosed disorder resulting from chronic or intermittent bleeding into the subarachnoid space, leading to deposition of blood products in the subpial layers of the meninges. Magnetic resonance imaging (MRI) shows a characteristic curvilinear pattern of hypointensity on its blood-sensitive sequences. Methods Series of cases collected from Brazilian centers. Results We studied 13 cases of patients presenting with progressive histories of neurological dysfunction caused by SS-CNS. The most frequent clinical findings in these patients were progressive gait ataxia, hearing loss, hyperreflexia and cognitive dysfunction. The diagnoses of SS-CNS were made seven months to 30 years after the disease onset. Conclusion SS-CNS is a rare disease that may remain undiagnosed for long periods. Awareness of this condition is essential for the clinician. |
| first_indexed | 2024-12-22T08:00:12Z |
| format | Article |
| id | doaj.art-6be6834078fe4f85b8a147c7bc9a9ac2 |
| institution | Directory Open Access Journal |
| issn | 1678-4227 |
| language | English |
| last_indexed | 2024-12-22T08:00:12Z |
| publisher | Academia Brasileira de Neurologia (ABNEURO) |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj.art-6be6834078fe4f85b8a147c7bc9a9ac22022-12-21T18:33:17ZengAcademia Brasileira de Neurologia (ABNEURO)Arquivos de Neuro-Psiquiatria1678-4227752929510.1590/0004-282x20170001S0004-282X2017000200004Superficial siderosis of the central nervous system is a rare and possibly underdiagnosed disorderYara Dadalti FragosoTarso AdoniJoseph Bruno Bidin BrooksSidney GomesMarcus Vinicius Magno GoncalvesCassio Lemos JovemAndre Palma da Cunha MattaJoao Filipe OliveiraFabio SiquinelliCarlos Bernardo TauilGuilherme Navarro TroianiPaulo Roberto WilleABSTRACT Superficial siderosis (SS) of the central nervous system (CNS) is a rare and possibly underdiagnosed disorder resulting from chronic or intermittent bleeding into the subarachnoid space, leading to deposition of blood products in the subpial layers of the meninges. Magnetic resonance imaging (MRI) shows a characteristic curvilinear pattern of hypointensity on its blood-sensitive sequences. Methods Series of cases collected from Brazilian centers. Results We studied 13 cases of patients presenting with progressive histories of neurological dysfunction caused by SS-CNS. The most frequent clinical findings in these patients were progressive gait ataxia, hearing loss, hyperreflexia and cognitive dysfunction. The diagnoses of SS-CNS were made seven months to 30 years after the disease onset. Conclusion SS-CNS is a rare disease that may remain undiagnosed for long periods. Awareness of this condition is essential for the clinician.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000200004&lng=en&tlng=ensideroseencéfaloperda auditivaataxia |
| spellingShingle | Yara Dadalti Fragoso Tarso Adoni Joseph Bruno Bidin Brooks Sidney Gomes Marcus Vinicius Magno Goncalves Cassio Lemos Jovem Andre Palma da Cunha Matta Joao Filipe Oliveira Fabio Siquinelli Carlos Bernardo Tauil Guilherme Navarro Troiani Paulo Roberto Wille Superficial siderosis of the central nervous system is a rare and possibly underdiagnosed disorder Arquivos de Neuro-Psiquiatria siderose encéfalo perda auditiva ataxia |
| title | Superficial siderosis of the central nervous system is a rare and possibly underdiagnosed disorder |
| title_full | Superficial siderosis of the central nervous system is a rare and possibly underdiagnosed disorder |
| title_fullStr | Superficial siderosis of the central nervous system is a rare and possibly underdiagnosed disorder |
| title_full_unstemmed | Superficial siderosis of the central nervous system is a rare and possibly underdiagnosed disorder |
| title_short | Superficial siderosis of the central nervous system is a rare and possibly underdiagnosed disorder |
| title_sort | superficial siderosis of the central nervous system is a rare and possibly underdiagnosed disorder |
| topic | siderose encéfalo perda auditiva ataxia |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2017000200004&lng=en&tlng=en |
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