Emerging Role of HDACs in Regeneration and Ageing in the Peripheral Nervous System: Repair Schwann Cells as Pivotal Targets

Emerging Role of HDACs in Regeneration and Ageing in the Peripheral Nervous System: Repair Schwann Cells as Pivotal Targets

The peripheral nervous system (PNS) has a remarkable regenerative capacity in comparison to the central nervous system (CNS), a phenomenon that is impaired during ageing. The ability of PNS axons to regenerate after injury is due to Schwann cells (SC) being reprogrammed into a repair phenotype calle...

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Bibliographic Details
Main Authors: Jose A. Gomez-Sanchez, Nikiben Patel, Fernanda Martirena, Shaline V. Fazal, Clara Mutschler, Hugo Cabedo
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
Schwann cell
repair Schwann cell
HDACs
nerve injury
nerve regeneration
myelin
Online Access:https://www.mdpi.com/1422-0067/23/6/2996

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