Peculiarities of polymorphism of <i>Helicobacter pylori</i> virulence genes and IL-1 genes in peptic ulcer of stomach and duodenum, associated with <i>Helicobacter pylori</i>
The prevalence of H.pylori virulence genes (iceA, cagA, babA2, vacA) as well as the distribution of the IL-1 genes was studied in patients with H.pylori-associated gastric and duodenal ulcer disease. VacA s1/m2 iceA1 cagA+ и vacA s1/m2 iceA1 cagA+ babA2 genotypes of H. pylori were shown to be preval...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Siberian State Medical University (Tomsk)
2005-12-01
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| Series: | Бюллетень сибирской медицины |
| Subjects: | |
| Online Access: | https://bulletin.ssmu.ru/jour/article/view/3946 |
| _version_ | 1797873310734745600 |
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| author | O. A. Tchernova E. R. Nasybullina O. V. Gorshkov G. F. Shaimardanova V. M. Tchernov R. A. Abdulkhakov |
| author_facet | O. A. Tchernova E. R. Nasybullina O. V. Gorshkov G. F. Shaimardanova V. M. Tchernov R. A. Abdulkhakov |
| author_sort | O. A. Tchernova |
| collection | DOAJ |
| description | The prevalence of H.pylori virulence genes (iceA, cagA, babA2, vacA) as well as the distribution of the IL-1 genes was studied in patients with H.pylori-associated gastric and duodenal ulcer disease. VacA s1/m2 iceA1 cagA+ и vacA s1/m2 iceA1 cagA+ babA2 genotypes of H. pylori were shown to be prevalent in the clinic isolates. Four patients were found to be infected with Ureaplasma urealyticum. The combination of the IL‑1B ‑511*Т / IL‑1B +3954*C / IL-1RN*2 alleles was shown to be prevalent among the patients with gastric and duodenal ulcer disease. The correlation between the H. pylori genotypes, the IL-1 genes and the peculiarities of ulcer disease was not found. |
| first_indexed | 2024-04-10T01:13:06Z |
| format | Article |
| id | doaj.art-6be74f92485b414ea70f88c6ba6bda56 |
| institution | Directory Open Access Journal |
| issn | 1682-0363 1819-3684 |
| language | English |
| last_indexed | 2024-04-10T01:13:06Z |
| publishDate | 2005-12-01 |
| publisher | Siberian State Medical University (Tomsk) |
| record_format | Article |
| series | Бюллетень сибирской медицины |
| spelling | doaj.art-6be74f92485b414ea70f88c6ba6bda562023-03-13T09:58:05ZengSiberian State Medical University (Tomsk)Бюллетень сибирской медицины1682-03631819-36842005-12-0140313510.20538/1682-0363-2005-0-31-352551Peculiarities of polymorphism of <i>Helicobacter pylori</i> virulence genes and IL-1 genes in peptic ulcer of stomach and duodenum, associated with <i>Helicobacter pylori</i>O. A. Tchernova0E. R. Nasybullina1O. V. Gorshkov2G. F. Shaimardanova3V. M. Tchernov4R. A. Abdulkhakov5Казанский институт биохимии и биофизики КазНЦ РАНКазанский институт биохимии и биофизики КазНЦ РАНКазанский институт биохимии и биофизики КазНЦ РАНКазанский институт биохимии и биофизики КазНЦ РАНКазанский институт биохимии и биофизики КазНЦ РАНКазанский государственный медицинский университетThe prevalence of H.pylori virulence genes (iceA, cagA, babA2, vacA) as well as the distribution of the IL-1 genes was studied in patients with H.pylori-associated gastric and duodenal ulcer disease. VacA s1/m2 iceA1 cagA+ и vacA s1/m2 iceA1 cagA+ babA2 genotypes of H. pylori were shown to be prevalent in the clinic isolates. Four patients were found to be infected with Ureaplasma urealyticum. The combination of the IL‑1B ‑511*Т / IL‑1B +3954*C / IL-1RN*2 alleles was shown to be prevalent among the patients with gastric and duodenal ulcer disease. The correlation between the H. pylori genotypes, the IL-1 genes and the peculiarities of ulcer disease was not found.https://bulletin.ssmu.ru/jour/article/view/3946факторы вирулентности helicobacter pyloriцитокины семейства ил-1генотипированиеязвенная болезньперсистенцияureaplasma urealyticum |
| spellingShingle | O. A. Tchernova E. R. Nasybullina O. V. Gorshkov G. F. Shaimardanova V. M. Tchernov R. A. Abdulkhakov Peculiarities of polymorphism of <i>Helicobacter pylori</i> virulence genes and IL-1 genes in peptic ulcer of stomach and duodenum, associated with <i>Helicobacter pylori</i> Бюллетень сибирской медицины факторы вирулентности helicobacter pylori цитокины семейства ил-1 генотипирование язвенная болезнь персистенция ureaplasma urealyticum |
| title | Peculiarities of polymorphism of <i>Helicobacter pylori</i> virulence genes and IL-1 genes in peptic ulcer of stomach and duodenum, associated with <i>Helicobacter pylori</i> |
| title_full | Peculiarities of polymorphism of <i>Helicobacter pylori</i> virulence genes and IL-1 genes in peptic ulcer of stomach and duodenum, associated with <i>Helicobacter pylori</i> |
| title_fullStr | Peculiarities of polymorphism of <i>Helicobacter pylori</i> virulence genes and IL-1 genes in peptic ulcer of stomach and duodenum, associated with <i>Helicobacter pylori</i> |
| title_full_unstemmed | Peculiarities of polymorphism of <i>Helicobacter pylori</i> virulence genes and IL-1 genes in peptic ulcer of stomach and duodenum, associated with <i>Helicobacter pylori</i> |
| title_short | Peculiarities of polymorphism of <i>Helicobacter pylori</i> virulence genes and IL-1 genes in peptic ulcer of stomach and duodenum, associated with <i>Helicobacter pylori</i> |
| title_sort | peculiarities of polymorphism of i helicobacter pylori i virulence genes and il 1 genes in peptic ulcer of stomach and duodenum associated with i helicobacter pylori i |
| topic | факторы вирулентности helicobacter pylori цитокины семейства ил-1 генотипирование язвенная болезнь персистенция ureaplasma urealyticum |
| url | https://bulletin.ssmu.ru/jour/article/view/3946 |
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