Seroepidemiology of Herpes Simplex Virus Type 1 and 2 in Northern Iran
Background: Herpes simplex virus (HSV) type 1 and 2 are common infectious agents worldwide. Data on prevalence of HSV-1 and HSV-2 infection are limited in Asia, especially in Iran. The aim of this study was to determine the seroprevalence of HSV type 1 and 2 based on age, gender, marital status, edu...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2012-08-01
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| Series: | Iranian Journal of Public Health |
| Subjects: | |
| Online Access: | https://ijph.tums.ac.ir/index.php/ijph/article/view/2535 |
| _version_ | 1818880537142493184 |
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| author | S Rezaei-Chaparpordi M Assmar N Amirmozafari L Modiri A Massiha S Shokri-Fashtali Z Gholizadeh S Akbari |
| author_facet | S Rezaei-Chaparpordi M Assmar N Amirmozafari L Modiri A Massiha S Shokri-Fashtali Z Gholizadeh S Akbari |
| author_sort | S Rezaei-Chaparpordi |
| collection | DOAJ |
| description | Background: Herpes simplex virus (HSV) type 1 and 2 are common infectious agents worldwide. Data on prevalence of HSV-1 and HSV-2 infection are limited in Asia, especially in Iran. The aim of this study was to determine the seroprevalence of HSV type 1 and 2 based on age, gender, marital status, education, living area, job, symptoms and history of disease variables.
Methods: The study population included 800 randomly selected persons from laboratories in Gilan Province, Iran, from 2010 to 2011. Demographic data gathered by a well-designed questionnaire and for serological studies, blood samples were collected and centrifuged. ELISA HSV-1, 2 and HSV-2 specific ELISA kits were used to determine IgG type specific antibodies in sera samples. Person's chi-square test was applied to compare HSV-1 and HSV-2 seropositivities.
Results: HSV-1 and HSV-2 IgG antibodies were positive in 467 (58.4%) and 28 (3.5%) subjects, respectively. There was significant correlation between age, marital status, job, symptoms, history of disease and HSV seroprevalence (P<0.05).
Conclusion: Our findings were in agreement with prior studies in which HSV-1 infections was more prevalent than HSV-2 and seropositivity increased with age. |
| first_indexed | 2024-12-19T14:47:32Z |
| format | Article |
| id | doaj.art-6beb511fd75341998958cc0f24acea12 |
| institution | Directory Open Access Journal |
| issn | 2251-6085 2251-6093 |
| language | English |
| last_indexed | 2024-12-19T14:47:32Z |
| publishDate | 2012-08-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Public Health |
| spelling | doaj.art-6beb511fd75341998958cc0f24acea122022-12-21T20:16:55ZengTehran University of Medical SciencesIranian Journal of Public Health2251-60852251-60932012-08-01418Seroepidemiology of Herpes Simplex Virus Type 1 and 2 in Northern IranS Rezaei-Chaparpordi0M Assmar1N Amirmozafari2L Modiri3A Massiha4S Shokri-Fashtali5Z Gholizadeh6S Akbari7 Background: Herpes simplex virus (HSV) type 1 and 2 are common infectious agents worldwide. Data on prevalence of HSV-1 and HSV-2 infection are limited in Asia, especially in Iran. The aim of this study was to determine the seroprevalence of HSV type 1 and 2 based on age, gender, marital status, education, living area, job, symptoms and history of disease variables. Methods: The study population included 800 randomly selected persons from laboratories in Gilan Province, Iran, from 2010 to 2011. Demographic data gathered by a well-designed questionnaire and for serological studies, blood samples were collected and centrifuged. ELISA HSV-1, 2 and HSV-2 specific ELISA kits were used to determine IgG type specific antibodies in sera samples. Person's chi-square test was applied to compare HSV-1 and HSV-2 seropositivities. Results: HSV-1 and HSV-2 IgG antibodies were positive in 467 (58.4%) and 28 (3.5%) subjects, respectively. There was significant correlation between age, marital status, job, symptoms, history of disease and HSV seroprevalence (P<0.05). Conclusion: Our findings were in agreement with prior studies in which HSV-1 infections was more prevalent than HSV-2 and seropositivity increased with age.https://ijph.tums.ac.ir/index.php/ijph/article/view/2535HSV-1HSV-2ELISAPrevalenceIran |
| spellingShingle | S Rezaei-Chaparpordi M Assmar N Amirmozafari L Modiri A Massiha S Shokri-Fashtali Z Gholizadeh S Akbari Seroepidemiology of Herpes Simplex Virus Type 1 and 2 in Northern Iran Iranian Journal of Public Health HSV-1 HSV-2 ELISA Prevalence Iran |
| title | Seroepidemiology of Herpes Simplex Virus Type 1 and 2 in Northern Iran |
| title_full | Seroepidemiology of Herpes Simplex Virus Type 1 and 2 in Northern Iran |
| title_fullStr | Seroepidemiology of Herpes Simplex Virus Type 1 and 2 in Northern Iran |
| title_full_unstemmed | Seroepidemiology of Herpes Simplex Virus Type 1 and 2 in Northern Iran |
| title_short | Seroepidemiology of Herpes Simplex Virus Type 1 and 2 in Northern Iran |
| title_sort | seroepidemiology of herpes simplex virus type 1 and 2 in northern iran |
| topic | HSV-1 HSV-2 ELISA Prevalence Iran |
| url | https://ijph.tums.ac.ir/index.php/ijph/article/view/2535 |
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