Automated approach for the evaluation of glutathione-S-transferase P1-1 inhibition by organometallic anticancer compounds

Automated approach for the evaluation of glutathione-S-transferase P1-1 inhibition by organometallic anticancer compounds

A novel automated method based on sequential injection analysis (SIA), a non-segmented flow injection technique, was developed to evaluate glutathione S-transferase P1-1 (GST P1-1) activity in the presence of organometallic complexes with putative anticancer activity. The assay is based on the react...

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Bibliographic Details
Main Authors:	Sarah A. P. Pereira, A. Catarina Baptista L, Lorenzo Biancalana, Fabio Marchetti, Paul J. Dyson, M. Lúcia M. F. S. Saraiva
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2022-05-01
Series:	Journal of Enzyme Inhibition and Medicinal Chemistry
Subjects:	Sequential injection analysis (SIA) glutathione S-transferase P1-1 enzyme inhibition assays anticancer metal complexes
Online Access:	https://www.tandfonline.com/doi/10.1080/14756366.2022.2073443

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