Comparison of Two Strategies for Hypercholesterolemia Detection through Point-of-Care Testing
Background: Childhood dyslipidemia is a common condition that can lead to atherosclerotic cardiovascular disease in adulthood. It is usually multifactorial. Screening for cholesterol disorders in children varies based on risk factors, with some guidelines recommending cascade screening for children...
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| Format: | Article |
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MDPI AG
2024-01-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/14/2/143 |
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| author | Héctor Eliud Arriaga-Cázares David Vega-Morales Carlos Alberto Moreno-Treviño Juana Lorena Juarez-Juarez Carlos Azael Pérez-Arizmendi Alexandro J. Martagón-Rosado |
| author_facet | Héctor Eliud Arriaga-Cázares David Vega-Morales Carlos Alberto Moreno-Treviño Juana Lorena Juarez-Juarez Carlos Azael Pérez-Arizmendi Alexandro J. Martagón-Rosado |
| author_sort | Héctor Eliud Arriaga-Cázares |
| collection | DOAJ |
| description | Background: Childhood dyslipidemia is a common condition that can lead to atherosclerotic cardiovascular disease in adulthood. It is usually multifactorial. Screening for cholesterol disorders in children varies based on risk factors, with some guidelines recommending cascade screening for children with a clear family history of familial hypercholesterolemia, targeted screening for those with specific risk factors, and universal screening. Point-of-care testing (POCT) cholesterol tests offer potential advantages, including ease of use, portability, increased patient access, low cost, fewer medical or laboratory visits, and instant results. This study aimed to evaluate the effect of POCT cholesterol screening on the diagnosis of hypercholesterolemia in children in a family practice setting. Methods: We used a POCT cholesterol analyzer to perform two different (universal and targeted) screening approaches for dyslipidemia in children. We used the NCEP guidelines for the classification of the results. Results: We screened 183 children, 105 in the universal screening group and 78 in the targeted screening group. Eight patients in the targeted screening group had elevated cholesterol levels (<i>p</i> = 0.02). Conclusions: All participants received instant feedback and recommendations. Using a targeted screening approach, POCT could be a practical and effective tool for identifying at-risk children with hypercholesterolemia. |
| first_indexed | 2024-03-08T11:00:09Z |
| format | Article |
| id | doaj.art-6bef659ebdff49eeb948711dd2decd91 |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-08T11:00:09Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-6bef659ebdff49eeb948711dd2decd912024-01-26T16:00:51ZengMDPI AGDiagnostics2075-44182024-01-0114214310.3390/diagnostics14020143Comparison of Two Strategies for Hypercholesterolemia Detection through Point-of-Care TestingHéctor Eliud Arriaga-Cázares0David Vega-Morales1Carlos Alberto Moreno-Treviño2Juana Lorena Juarez-Juarez3Carlos Azael Pérez-Arizmendi4Alexandro J. Martagón-Rosado5Instituto Mexicano del Seguro Social, Hospital de Traumatología y Ortopedia N.º 21, Monterrey 64000, MexicoInstituto Mexicano del Seguro Social, Hospital General de Zona 17, Monterrey 64420, MexicoInstituto Mexicano del Seguro Social, Unidad de Medicina Familiar 26, Monterrey 64117, MexicoInstituto Mexicano del Seguro Social, Unidad de Medicina Familiar 26, Monterrey 64117, MexicoInstituto Mexicano del Seguro Social, Unidad de Medicina Familiar 26, Monterrey 64117, MexicoEscuela de Medicina, Instituto Tecnológico y de Estudios Superiores de Monterrey, Monterrey 64849, MexicoBackground: Childhood dyslipidemia is a common condition that can lead to atherosclerotic cardiovascular disease in adulthood. It is usually multifactorial. Screening for cholesterol disorders in children varies based on risk factors, with some guidelines recommending cascade screening for children with a clear family history of familial hypercholesterolemia, targeted screening for those with specific risk factors, and universal screening. Point-of-care testing (POCT) cholesterol tests offer potential advantages, including ease of use, portability, increased patient access, low cost, fewer medical or laboratory visits, and instant results. This study aimed to evaluate the effect of POCT cholesterol screening on the diagnosis of hypercholesterolemia in children in a family practice setting. Methods: We used a POCT cholesterol analyzer to perform two different (universal and targeted) screening approaches for dyslipidemia in children. We used the NCEP guidelines for the classification of the results. Results: We screened 183 children, 105 in the universal screening group and 78 in the targeted screening group. Eight patients in the targeted screening group had elevated cholesterol levels (<i>p</i> = 0.02). Conclusions: All participants received instant feedback and recommendations. Using a targeted screening approach, POCT could be a practical and effective tool for identifying at-risk children with hypercholesterolemia.https://www.mdpi.com/2075-4418/14/2/143childmass screeninghypercholesterolemiadyslipidemia |
| spellingShingle | Héctor Eliud Arriaga-Cázares David Vega-Morales Carlos Alberto Moreno-Treviño Juana Lorena Juarez-Juarez Carlos Azael Pérez-Arizmendi Alexandro J. Martagón-Rosado Comparison of Two Strategies for Hypercholesterolemia Detection through Point-of-Care Testing Diagnostics child mass screening hypercholesterolemia dyslipidemia |
| title | Comparison of Two Strategies for Hypercholesterolemia Detection through Point-of-Care Testing |
| title_full | Comparison of Two Strategies for Hypercholesterolemia Detection through Point-of-Care Testing |
| title_fullStr | Comparison of Two Strategies for Hypercholesterolemia Detection through Point-of-Care Testing |
| title_full_unstemmed | Comparison of Two Strategies for Hypercholesterolemia Detection through Point-of-Care Testing |
| title_short | Comparison of Two Strategies for Hypercholesterolemia Detection through Point-of-Care Testing |
| title_sort | comparison of two strategies for hypercholesterolemia detection through point of care testing |
| topic | child mass screening hypercholesterolemia dyslipidemia |
| url | https://www.mdpi.com/2075-4418/14/2/143 |
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