Energetic Calculations to Decipher pH-Dependent Oligomerization and Domain Swapping of Proteins.

Domain swapping mechanism is a specialised mode of oligomerization of proteins in which part of a protein is exchanged in a non-covalent manner between constituent subunits. This mechanism is highly affected by several physiological conditions. Here, we present a detailed analysis ofthe effect of pH...

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Bibliographic Details
Main Authors: Prashant Shingate, Jim Warwicker, Ramanathan Sowdhamini
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4456399?pdf=render