Analysis of spectrum and drug sensitivity of bacteria in the aqueous humor or vitreous of patients at an early stage of penetrating ocular trauma
AIM:To analyze the spectrum and antibiotic sensitivity of bacteria in the aqueous humor and vitreous immediately following the occurrence of penetrating ocular trauma.<p>METHODS: Aqueous humor or vitreous specimens were collected from 45 eyes of 45 patients with penetrating ocular trauma befor...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Press of International Journal of Ophthalmology (IJO PRESS)
2016-05-01
|
| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2016/5/201605006.pdf |
| _version_ | 1818030718719098880 |
|---|---|
| author | Yan-Fen Hu Ni Tian Yue-Zhen Guo Hui-Ying Li |
| author_facet | Yan-Fen Hu Ni Tian Yue-Zhen Guo Hui-Ying Li |
| author_sort | Yan-Fen Hu |
| collection | DOAJ |
| description | AIM:To analyze the spectrum and antibiotic sensitivity of bacteria in the aqueous humor and vitreous immediately following the occurrence of penetrating ocular trauma.<p>METHODS: Aqueous humor or vitreous specimens were collected from 45 eyes of 45 patients with penetrating ocular trauma before operations. The specimens were prepared for bacterial culture and the associated sensitivity tests to several commonly used antibiotics.<p>RESULTS: Fifteen eyes of all the patients were found to be positive with bacterial infection, and the most frequently identified bacteria was staphylococcus epidermidis, which accounted for 67.7%(10/15)of all identified cases. All identified bacteria were sensitive to ciprofloxacin and ofloxacin, and less sensitive to cefoperazone. Most of them were resistant to gentamycin, rifampin and chloramphenicol. Accompanying intraocular foreign body or sclera wound were associated with positive bacterial cultures(<i>χ</i><sub>1</sub><sup>2</sup>=6.544, <i>P</i><sub>1</sub>=0.016; <i>χ</i><sub>2</sub><sup>2</sup>=4.5, <i>P</i><sub>2</sub>=0.034). Causes of injury(<i>χ</i><sup>2</sup>=1.667,<i>P</i>=0.197), lens rupture(<i>χ</i><sup>2</sup>=1.125,<i>P</i>=0.352)or locations where the specimen was collected(<i>χ</i><sup>2</sup>=1.667,<i>P</i>=0.197)did not contribute to the difference in the positive rates of bacterial cultures.<p>CONCLUSION:In patients with penetrating ocular trauma, the major bacteria entering into the eye was staphylococcus epidermidis. Fluro-Quinolones can be used as the first-line antibiotics for prophylactic treatment. Cefoperazone can be taken as a second choice. |
| first_indexed | 2024-12-10T05:40:02Z |
| format | Article |
| id | doaj.art-6bf802937a8a4cdd8fa48ef730b1d3fe |
| institution | Directory Open Access Journal |
| issn | 1672-5123 1672-5123 |
| language | English |
| last_indexed | 2024-12-10T05:40:02Z |
| publishDate | 2016-05-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-6bf802937a8a4cdd8fa48ef730b1d3fe2022-12-22T02:00:19ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51231672-51232016-05-0116581882110.3980/j.issn.1672-5123.2016.5.06Analysis of spectrum and drug sensitivity of bacteria in the aqueous humor or vitreous of patients at an early stage of penetrating ocular traumaYan-Fen Hu0Ni Tian1Yue-Zhen Guo2Hui-Ying Li3Department of Ophthalmology, the Sixth Hospital of Nansha District, Guangzhou 511470, Guangdong Province, ChinaDepartment of Ophthalmology, the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine, Guangzhou 511470, Guangdong Province, ChinaDepartment of Ophthalmology, the Sixth Hospital of Nansha District, Guangzhou 511470, Guangdong Province, ChinaDepartment of Ophthalmology, the Sixth Hospital of Nansha District, Guangzhou 511470, Guangdong Province, ChinaAIM:To analyze the spectrum and antibiotic sensitivity of bacteria in the aqueous humor and vitreous immediately following the occurrence of penetrating ocular trauma.<p>METHODS: Aqueous humor or vitreous specimens were collected from 45 eyes of 45 patients with penetrating ocular trauma before operations. The specimens were prepared for bacterial culture and the associated sensitivity tests to several commonly used antibiotics.<p>RESULTS: Fifteen eyes of all the patients were found to be positive with bacterial infection, and the most frequently identified bacteria was staphylococcus epidermidis, which accounted for 67.7%(10/15)of all identified cases. All identified bacteria were sensitive to ciprofloxacin and ofloxacin, and less sensitive to cefoperazone. Most of them were resistant to gentamycin, rifampin and chloramphenicol. Accompanying intraocular foreign body or sclera wound were associated with positive bacterial cultures(<i>χ</i><sub>1</sub><sup>2</sup>=6.544, <i>P</i><sub>1</sub>=0.016; <i>χ</i><sub>2</sub><sup>2</sup>=4.5, <i>P</i><sub>2</sub>=0.034). Causes of injury(<i>χ</i><sup>2</sup>=1.667,<i>P</i>=0.197), lens rupture(<i>χ</i><sup>2</sup>=1.125,<i>P</i>=0.352)or locations where the specimen was collected(<i>χ</i><sup>2</sup>=1.667,<i>P</i>=0.197)did not contribute to the difference in the positive rates of bacterial cultures.<p>CONCLUSION:In patients with penetrating ocular trauma, the major bacteria entering into the eye was staphylococcus epidermidis. Fluro-Quinolones can be used as the first-line antibiotics for prophylactic treatment. Cefoperazone can be taken as a second choice.http://ies.ijo.cn/cn_publish/2016/5/201605006.pdfpenetrating ocular traumabacterial cultureaqueous humorvitreous |
| spellingShingle | Yan-Fen Hu Ni Tian Yue-Zhen Guo Hui-Ying Li Analysis of spectrum and drug sensitivity of bacteria in the aqueous humor or vitreous of patients at an early stage of penetrating ocular trauma Guoji Yanke Zazhi penetrating ocular trauma bacterial culture aqueous humor vitreous |
| title | Analysis of spectrum and drug sensitivity of bacteria in the aqueous humor or vitreous of patients at an early stage of penetrating ocular trauma |
| title_full | Analysis of spectrum and drug sensitivity of bacteria in the aqueous humor or vitreous of patients at an early stage of penetrating ocular trauma |
| title_fullStr | Analysis of spectrum and drug sensitivity of bacteria in the aqueous humor or vitreous of patients at an early stage of penetrating ocular trauma |
| title_full_unstemmed | Analysis of spectrum and drug sensitivity of bacteria in the aqueous humor or vitreous of patients at an early stage of penetrating ocular trauma |
| title_short | Analysis of spectrum and drug sensitivity of bacteria in the aqueous humor or vitreous of patients at an early stage of penetrating ocular trauma |
| title_sort | analysis of spectrum and drug sensitivity of bacteria in the aqueous humor or vitreous of patients at an early stage of penetrating ocular trauma |
| topic | penetrating ocular trauma bacterial culture aqueous humor vitreous |
| url | http://ies.ijo.cn/cn_publish/2016/5/201605006.pdf |
| work_keys_str_mv | AT yanfenhu analysisofspectrumanddrugsensitivityofbacteriaintheaqueoushumororvitreousofpatientsatanearlystageofpenetratingoculartrauma AT nitian analysisofspectrumanddrugsensitivityofbacteriaintheaqueoushumororvitreousofpatientsatanearlystageofpenetratingoculartrauma AT yuezhenguo analysisofspectrumanddrugsensitivityofbacteriaintheaqueoushumororvitreousofpatientsatanearlystageofpenetratingoculartrauma AT huiyingli analysisofspectrumanddrugsensitivityofbacteriaintheaqueoushumororvitreousofpatientsatanearlystageofpenetratingoculartrauma |