COLLAGEN: STRUCTURE, METABOLISM, PRODUCTION AND INDUSTRIAL APPLICATION
This review presents the current scientific literature data about structure, properties, and functions of collagen, which is known as one of the most abundant human and animal proteins. The building of collagen molecule from the primary structure to submolecular formations, the main stages of its sy...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry
2020-10-01
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| Series: | Biotechnologia Acta |
| Subjects: | |
| Online Access: | http://biotechnology.kiev.ua/images/storage/5_2020/gulevsky_5_2020.pdf |
| _version_ | 1797717603331866624 |
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| author | A. K. Gulevsky I. I. Shcheniavsky |
| author_facet | A. K. Gulevsky I. I. Shcheniavsky |
| author_sort | A. K. Gulevsky |
| collection | DOAJ |
| description | This review presents the current scientific literature data about structure, properties, and functions of collagen, which is known as one of the most abundant human and animal proteins. The building of collagen molecule from the primary structure to submolecular formations, the main stages of its synthesis and biodegradation are briefly described. The information about collagen diversity, its features and metabolic ways in various tissues, including skin, tendons, bones, etc. is presented. The problems of pathologies caused by collagen synthesis and breakdown disorders as well as age-related changes in collagen properties and their causes are discussed.
A comparative analysis of the advantages and disadvantages of collagen and its derivatives obtaining from various sources (animals, marine, and recombinant) is given. The most productive methods for collagen extraction from various tissues are shown. The concept of collagen hydrolysis conditions influence on the physicochemical properties and biological activity of the obtained products is described.
The applications of collagen and its products in various fields of industrial activity, such as pharmaceutical, cosmetic industry and medicine, are discussed. Further prospective directions of fundamental and applied investigations in this area of research are outlined. |
| first_indexed | 2024-03-12T08:38:45Z |
| format | Article |
| id | doaj.art-6bfa12ff97ec4e0da85c93fe9e879279 |
| institution | Directory Open Access Journal |
| issn | 2410-7751 2410-776X |
| language | English |
| last_indexed | 2024-03-12T08:38:45Z |
| publishDate | 2020-10-01 |
| publisher | National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry |
| record_format | Article |
| series | Biotechnologia Acta |
| spelling | doaj.art-6bfa12ff97ec4e0da85c93fe9e8792792023-09-02T17:03:33ZengNational Academy of Sciences of Ukraine, Palladin Institute of BiochemistryBiotechnologia Acta2410-77512410-776X2020-10-011354261doi.org/10.15407/biotech13.05.042COLLAGEN: STRUCTURE, METABOLISM, PRODUCTION AND INDUSTRIAL APPLICATIONA. K. Gulevsky0 I. I. Shcheniavsky1Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, KharkivInstitute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, KharkivThis review presents the current scientific literature data about structure, properties, and functions of collagen, which is known as one of the most abundant human and animal proteins. The building of collagen molecule from the primary structure to submolecular formations, the main stages of its synthesis and biodegradation are briefly described. The information about collagen diversity, its features and metabolic ways in various tissues, including skin, tendons, bones, etc. is presented. The problems of pathologies caused by collagen synthesis and breakdown disorders as well as age-related changes in collagen properties and their causes are discussed. A comparative analysis of the advantages and disadvantages of collagen and its derivatives obtaining from various sources (animals, marine, and recombinant) is given. The most productive methods for collagen extraction from various tissues are shown. The concept of collagen hydrolysis conditions influence on the physicochemical properties and biological activity of the obtained products is described. The applications of collagen and its products in various fields of industrial activity, such as pharmaceutical, cosmetic industry and medicine, are discussed. Further prospective directions of fundamental and applied investigations in this area of research are outlined.http://biotechnology.kiev.ua/images/storage/5_2020/gulevsky_5_2020.pdfcollagen typescollagen metabolismsources of collagen productioncollagen hydrolysisapplication of collagen. |
| spellingShingle | A. K. Gulevsky I. I. Shcheniavsky COLLAGEN: STRUCTURE, METABOLISM, PRODUCTION AND INDUSTRIAL APPLICATION Biotechnologia Acta collagen types collagen metabolism sources of collagen production collagen hydrolysis application of collagen. |
| title | COLLAGEN: STRUCTURE, METABOLISM, PRODUCTION AND INDUSTRIAL APPLICATION |
| title_full | COLLAGEN: STRUCTURE, METABOLISM, PRODUCTION AND INDUSTRIAL APPLICATION |
| title_fullStr | COLLAGEN: STRUCTURE, METABOLISM, PRODUCTION AND INDUSTRIAL APPLICATION |
| title_full_unstemmed | COLLAGEN: STRUCTURE, METABOLISM, PRODUCTION AND INDUSTRIAL APPLICATION |
| title_short | COLLAGEN: STRUCTURE, METABOLISM, PRODUCTION AND INDUSTRIAL APPLICATION |
| title_sort | collagen structure metabolism production and industrial application |
| topic | collagen types collagen metabolism sources of collagen production collagen hydrolysis application of collagen. |
| url | http://biotechnology.kiev.ua/images/storage/5_2020/gulevsky_5_2020.pdf |
| work_keys_str_mv | AT akgulevsky collagenstructuremetabolismproductionandindustrialapplication AT iishcheniavsky collagenstructuremetabolismproductionandindustrialapplication |