The Effect of Pre-, Intra- and Postoperative Blood Glucose on Outcomes of Patients with Traumatic Brain Injury
Background: Traumatic brain injury is one of the important problems of world health with high mortality; probably, simultaneous hyperglycemia can intensify the harmful effects. Since there is no unique opinion in this regard, we aimed to study the effect of blood glucose at before, during and after...
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| Format: | Article |
| Language: | fas |
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Isfahan University of Medical Sciences
2016-02-01
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| Series: | مجله دانشکده پزشکی اصفهان |
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| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/5409 |
| _version_ | 1797709411236446208 |
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| author | Reyhanak Talakoub Mohammad Golparvar Elham Khodadoustan |
| author_facet | Reyhanak Talakoub Mohammad Golparvar Elham Khodadoustan |
| author_sort | Reyhanak Talakoub |
| collection | DOAJ |
| description | Background: Traumatic brain injury is one of the important problems of world health with high mortality; probably, simultaneous hyperglycemia can intensify the harmful effects. Since there is no unique opinion in this regard, we aimed to study the effect of blood glucose at before, during and after operation on outcome of patients with traumatic brain injury.
Methods: A hundred patients with traumatic brain injury were studied during a prospective clinical trial study. We divided patients according to their preoperative blood glucose level to two groups of normo- and hyperglycemic. We measured and recorded blood glucose level during and after operation, in addition to the heart rate, blood pressure, saturation of oxygen (SpO2), duration of mechanical ventilation and outcome of patients in both groups.
Findings: Heart rate was significantly higher at 15th (P = 0.027), 60th (P = 0.018), 105th (P = 0.010) minutes and in recovery room (P = 0.006) in hyperglycemic patients; but as a general, the changes in heart rates were not significant in both groups (P = 0.610). There was no difference in SpO2 at different times. The mean arterial pressure (MAP) was higher at 45th (P = 0.025) and 60th (P = 0.016) minutes during the surgery; but as a general, there were no significant difference in MAP between the two groups (P = 0.850). Duration of mechanical ventilation was significantly longer in hyperglycemic patients (P = 0.009).
Conclusion: According to our findings, elevated blood glucose patients with traumatic brain injury may results in some intraoperative hemodynamic changes and affect their outcome. Therefore, monitoring of blood glucose in these patients is suggested. |
| first_indexed | 2024-03-12T06:36:06Z |
| format | Article |
| id | doaj.art-6c060c04bf1044c89a6ff744ca1bd96d |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T06:36:06Z |
| publishDate | 2016-02-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-6c060c04bf1044c89a6ff744ca1bd96d2023-09-03T01:17:50ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2016-02-0133361206220692084The Effect of Pre-, Intra- and Postoperative Blood Glucose on Outcomes of Patients with Traumatic Brain InjuryReyhanak Talakoub0Mohammad Golparvar1Elham Khodadoustan2Associate Professor, Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, IranAssociate Professor, Anesthesiology and Critical Care Research Center, Isfahan University of Medical Sciences, Isfahan, IranStudent of Medicine, School of Medicine AND Student Research Committee, Isfahan University of Medical Sciences, Isfahan, IranBackground: Traumatic brain injury is one of the important problems of world health with high mortality; probably, simultaneous hyperglycemia can intensify the harmful effects. Since there is no unique opinion in this regard, we aimed to study the effect of blood glucose at before, during and after operation on outcome of patients with traumatic brain injury. Methods: A hundred patients with traumatic brain injury were studied during a prospective clinical trial study. We divided patients according to their preoperative blood glucose level to two groups of normo- and hyperglycemic. We measured and recorded blood glucose level during and after operation, in addition to the heart rate, blood pressure, saturation of oxygen (SpO2), duration of mechanical ventilation and outcome of patients in both groups. Findings: Heart rate was significantly higher at 15th (P = 0.027), 60th (P = 0.018), 105th (P = 0.010) minutes and in recovery room (P = 0.006) in hyperglycemic patients; but as a general, the changes in heart rates were not significant in both groups (P = 0.610). There was no difference in SpO2 at different times. The mean arterial pressure (MAP) was higher at 45th (P = 0.025) and 60th (P = 0.016) minutes during the surgery; but as a general, there were no significant difference in MAP between the two groups (P = 0.850). Duration of mechanical ventilation was significantly longer in hyperglycemic patients (P = 0.009). Conclusion: According to our findings, elevated blood glucose patients with traumatic brain injury may results in some intraoperative hemodynamic changes and affect their outcome. Therefore, monitoring of blood glucose in these patients is suggested.http://jims.mui.ac.ir/index.php/jims/article/view/5409Blood glucoseBrain injuryHemodynamic changesOutcome |
| spellingShingle | Reyhanak Talakoub Mohammad Golparvar Elham Khodadoustan The Effect of Pre-, Intra- and Postoperative Blood Glucose on Outcomes of Patients with Traumatic Brain Injury مجله دانشکده پزشکی اصفهان Blood glucose Brain injury Hemodynamic changes Outcome |
| title | The Effect of Pre-, Intra- and Postoperative Blood Glucose on Outcomes of Patients with Traumatic Brain Injury |
| title_full | The Effect of Pre-, Intra- and Postoperative Blood Glucose on Outcomes of Patients with Traumatic Brain Injury |
| title_fullStr | The Effect of Pre-, Intra- and Postoperative Blood Glucose on Outcomes of Patients with Traumatic Brain Injury |
| title_full_unstemmed | The Effect of Pre-, Intra- and Postoperative Blood Glucose on Outcomes of Patients with Traumatic Brain Injury |
| title_short | The Effect of Pre-, Intra- and Postoperative Blood Glucose on Outcomes of Patients with Traumatic Brain Injury |
| title_sort | effect of pre intra and postoperative blood glucose on outcomes of patients with traumatic brain injury |
| topic | Blood glucose Brain injury Hemodynamic changes Outcome |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/5409 |
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