Toxic effects of sirolimus and everolimus on the development and behavior of zebrafish embryos

Sirolimus and everolimus have been widely used in children. These mammalian target of rapamycin (mTOR) inhibitors have shown excellent efficacy not only in organ transplant patients as immunosuppressive agents but also in patients with some other diseases. However, whether mTOR inhibitors can affect...

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Bibliographic Details
Main Authors: Zixin Zhang, Tong Qiu, Jiangyuan Zhou, Xue Gong, Kaiying Yang, Xuepeng Zhang, Yuru Lan, Congxia Yang, Zilong Zhou, Yi Ji
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332223011952