Beneficial effects of Pleurotus albidus supplementation on body weight and food intake in healthy C57BL/6 mice
ABSTRACT: The current investigation intended to check the influence of Pleurotus albidus extract supplementation on body weight, food intake, glycemia, serum lipids, and oxidative stress parameters. Healthy male C57BL/6 mice were partitioned into two experimental groups: control and P. albidus. The...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co. Ltd.
2021-09-01
|
| Series: | Journal of Future Foods |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2772566921000094 |
| _version_ | 1811292603355758592 |
|---|---|
| author | Paola Quevedo da Costa Mariana Parron Paim Eduardo Echer dos Reis Patrick Türck Marli Camassola Paulo Cavalheiro Schenkel |
| author_facet | Paola Quevedo da Costa Mariana Parron Paim Eduardo Echer dos Reis Patrick Türck Marli Camassola Paulo Cavalheiro Schenkel |
| author_sort | Paola Quevedo da Costa |
| collection | DOAJ |
| description | ABSTRACT: The current investigation intended to check the influence of Pleurotus albidus extract supplementation on body weight, food intake, glycemia, serum lipids, and oxidative stress parameters. Healthy male C57BL/6 mice were partitioned into two experimental groups: control and P. albidus. The supplementation was performed by gavage (500 mg/kg) for 20 uninterrupted days. During this period, all animals received water and food ad libitum and they had their food ingestion and body weight monitored weekly. After, mice underwent an insulin sensitivity test, followed by euthanasia and biochemical analyses. P. albidus supplementation decreased the body weight and food intake, but it did not change other parameters in healthy mice. This work showed for the first time that the P. albidus extract supplementation presents a promising potential on body weight and food intake control. |
| first_indexed | 2024-04-13T04:48:45Z |
| format | Article |
| id | doaj.art-6c08aae7523e4fa68ea95c05e164cd35 |
| institution | Directory Open Access Journal |
| issn | 2772-5669 |
| language | English |
| last_indexed | 2024-04-13T04:48:45Z |
| publishDate | 2021-09-01 |
| publisher | KeAi Communications Co. Ltd. |
| record_format | Article |
| series | Journal of Future Foods |
| spelling | doaj.art-6c08aae7523e4fa68ea95c05e164cd352022-12-22T03:01:46ZengKeAi Communications Co. Ltd.Journal of Future Foods2772-56692021-09-011198103Beneficial effects of Pleurotus albidus supplementation on body weight and food intake in healthy C57BL/6 micePaola Quevedo da Costa0Mariana Parron Paim1Eduardo Echer dos Reis2Patrick Türck3Marli Camassola4Paulo Cavalheiro Schenkel5Department of Physiology and Pharmacology, Universidade Federal de Pelotas, Campus Capão do Leão 96900-010 Pelotas, BrazilDepartment of Physiology and Pharmacology, Universidade Federal de Pelotas, Campus Capão do Leão 96900-010 Pelotas, BrazilDepartment of Physiology, Universidade Federal do Rio Grande do Sul, Campus Centro 90050-170 Porto Alegre, Brazil; Enzymes and Biomass Laboratory, Institute of Biotechnology, Universidade de Caxias do Sul, Rua Francisco Getúlio Vargas 1130, 95070-560, Caxias do Sul, RS, BrazilDepartment of Physiology, Universidade Federal do Rio Grande do Sul, Campus Centro 90050-170 Porto Alegre, BrazilEnzymes and Biomass Laboratory, Institute of Biotechnology, Universidade de Caxias do Sul, Rua Francisco Getúlio Vargas 1130, 95070-560, Caxias do Sul, RS, BrazilDepartment of Physiology and Pharmacology, Universidade Federal de Pelotas, Campus Capão do Leão 96900-010 Pelotas, Brazil; Corresponding author: Department of Physiology and Pharmacology, Universidade Federal de Pelotas, Campus Capão do Leão 96900-010 Pelotas, BrazilABSTRACT: The current investigation intended to check the influence of Pleurotus albidus extract supplementation on body weight, food intake, glycemia, serum lipids, and oxidative stress parameters. Healthy male C57BL/6 mice were partitioned into two experimental groups: control and P. albidus. The supplementation was performed by gavage (500 mg/kg) for 20 uninterrupted days. During this period, all animals received water and food ad libitum and they had their food ingestion and body weight monitored weekly. After, mice underwent an insulin sensitivity test, followed by euthanasia and biochemical analyses. P. albidus supplementation decreased the body weight and food intake, but it did not change other parameters in healthy mice. This work showed for the first time that the P. albidus extract supplementation presents a promising potential on body weight and food intake control.http://www.sciencedirect.com/science/article/pii/S2772566921000094Blood glucoseGlutathione peroxidaseInsulinPleurotusTriglycerides |
| spellingShingle | Paola Quevedo da Costa Mariana Parron Paim Eduardo Echer dos Reis Patrick Türck Marli Camassola Paulo Cavalheiro Schenkel Beneficial effects of Pleurotus albidus supplementation on body weight and food intake in healthy C57BL/6 mice Journal of Future Foods Blood glucose Glutathione peroxidase Insulin Pleurotus Triglycerides |
| title | Beneficial effects of Pleurotus albidus supplementation on body weight and food intake in healthy C57BL/6 mice |
| title_full | Beneficial effects of Pleurotus albidus supplementation on body weight and food intake in healthy C57BL/6 mice |
| title_fullStr | Beneficial effects of Pleurotus albidus supplementation on body weight and food intake in healthy C57BL/6 mice |
| title_full_unstemmed | Beneficial effects of Pleurotus albidus supplementation on body weight and food intake in healthy C57BL/6 mice |
| title_short | Beneficial effects of Pleurotus albidus supplementation on body weight and food intake in healthy C57BL/6 mice |
| title_sort | beneficial effects of pleurotus albidus supplementation on body weight and food intake in healthy c57bl 6 mice |
| topic | Blood glucose Glutathione peroxidase Insulin Pleurotus Triglycerides |
| url | http://www.sciencedirect.com/science/article/pii/S2772566921000094 |
| work_keys_str_mv | AT paolaquevedodacosta beneficialeffectsofpleurotusalbidussupplementationonbodyweightandfoodintakeinhealthyc57bl6mice AT marianaparronpaim beneficialeffectsofpleurotusalbidussupplementationonbodyweightandfoodintakeinhealthyc57bl6mice AT eduardoecherdosreis beneficialeffectsofpleurotusalbidussupplementationonbodyweightandfoodintakeinhealthyc57bl6mice AT patrickturck beneficialeffectsofpleurotusalbidussupplementationonbodyweightandfoodintakeinhealthyc57bl6mice AT marlicamassola beneficialeffectsofpleurotusalbidussupplementationonbodyweightandfoodintakeinhealthyc57bl6mice AT paulocavalheiroschenkel beneficialeffectsofpleurotusalbidussupplementationonbodyweightandfoodintakeinhealthyc57bl6mice |