Low body mass index in long standing rheumatoid arthritis: relation to RA disease activity and functional indices
The aim of the work was to study the relationship between the body mass index (BMI) in longstanding rheumatoid arthritis (RA) and RA disease activity and functional indices. This study included 105 RA patients. For all patients, we recorded the presence of erosions on radiographs, the presence of su...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2018-07-01
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| Series: | Reumatismo |
| Subjects: | |
| Online Access: | https://www.reumatismo.org/index.php/reuma/article/view/999 |
| _version_ | 1811292537034375168 |
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| author | S.M. Gamal A.K. Alkemary M.A. Abdo A.H.M. El Dakrony |
| author_facet | S.M. Gamal A.K. Alkemary M.A. Abdo A.H.M. El Dakrony |
| author_sort | S.M. Gamal |
| collection | DOAJ |
| description | The aim of the work was to study the relationship between the body mass index (BMI) in longstanding rheumatoid arthritis (RA) and RA disease activity and functional indices. This study included 105 RA patients. For all patients, we recorded the presence of erosions on radiographs, the presence of subcutaneous nodules (SCN), the 28-tender joint count (TJC), 28-swollen joint count (SJC) scores, the visual analogue scale (VAS), physicians’ global assessments (PhGA), the erythrocyte sedimentation rate (ESR), and the rheumatoid factor (RF). The disease activity index (DAS28) and BMI were calculated and current treatment was recorded. Patients were divided into two groups: group I: BMI 25. Group I included 32 (30.5%) patients, whereas group II included 73 (69.5%) patients. There were statistically significant differences between the two groups regarding each of the following: SJC (p=0.006), erosions (p=0.006), DAS28 (p=0.016) and PhGA (p=0.007). All were higher in group I (underweight and normal) than in group II (overweight and obese). No statistically significant differences emerged regarding age (p=0.11), smoking (p=0.69), disease duration (p=0.46), TJC (p=0.14), SCN (p=1.00), HAQ (p=0.26), VAS (p=0.16), ESR (p=0.25), RF (p=0.54) and steroid cumulative dose (p=0.08). Low BMI in longstanding RA patients may indicate more active and erosive disease and it may be considered as a poor prognostic factor. |
| first_indexed | 2024-04-13T04:47:57Z |
| format | Article |
| id | doaj.art-6c0a5b7a764c41c08f81c9b8f8230761 |
| institution | Directory Open Access Journal |
| issn | 0048-7449 2240-2683 |
| language | English |
| last_indexed | 2024-04-13T04:47:57Z |
| publishDate | 2018-07-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Reumatismo |
| spelling | doaj.art-6c0a5b7a764c41c08f81c9b8f82307612022-12-22T03:01:48ZengPAGEPress PublicationsReumatismo0048-74492240-26832018-07-01702727710.4081/reumatismo.2018.999786Low body mass index in long standing rheumatoid arthritis: relation to RA disease activity and functional indicesS.M. Gamal0A.K. Alkemary1M.A. Abdo2A.H.M. El Dakrony3Rheumatology and Rehabilitation Department, Faculty of Medicine, Cairo UniversityInternal Medicine Department, Faculty of Medicine, Cairo UniversityRheumatology and Rehabilitation Department, Faculty of Medicine, Cairo UniversityRheumatology and Rehabilitation Department, Faculty of Medicine, Cairo UniversityThe aim of the work was to study the relationship between the body mass index (BMI) in longstanding rheumatoid arthritis (RA) and RA disease activity and functional indices. This study included 105 RA patients. For all patients, we recorded the presence of erosions on radiographs, the presence of subcutaneous nodules (SCN), the 28-tender joint count (TJC), 28-swollen joint count (SJC) scores, the visual analogue scale (VAS), physicians’ global assessments (PhGA), the erythrocyte sedimentation rate (ESR), and the rheumatoid factor (RF). The disease activity index (DAS28) and BMI were calculated and current treatment was recorded. Patients were divided into two groups: group I: BMI 25. Group I included 32 (30.5%) patients, whereas group II included 73 (69.5%) patients. There were statistically significant differences between the two groups regarding each of the following: SJC (p=0.006), erosions (p=0.006), DAS28 (p=0.016) and PhGA (p=0.007). All were higher in group I (underweight and normal) than in group II (overweight and obese). No statistically significant differences emerged regarding age (p=0.11), smoking (p=0.69), disease duration (p=0.46), TJC (p=0.14), SCN (p=1.00), HAQ (p=0.26), VAS (p=0.16), ESR (p=0.25), RF (p=0.54) and steroid cumulative dose (p=0.08). Low BMI in longstanding RA patients may indicate more active and erosive disease and it may be considered as a poor prognostic factor.https://www.reumatismo.org/index.php/reuma/article/view/999Rheumatoid arthritisBody mass indexDAS28Radiological erosions. |
| spellingShingle | S.M. Gamal A.K. Alkemary M.A. Abdo A.H.M. El Dakrony Low body mass index in long standing rheumatoid arthritis: relation to RA disease activity and functional indices Reumatismo Rheumatoid arthritis Body mass index DAS28 Radiological erosions. |
| title | Low body mass index in long standing rheumatoid arthritis: relation to RA disease activity and functional indices |
| title_full | Low body mass index in long standing rheumatoid arthritis: relation to RA disease activity and functional indices |
| title_fullStr | Low body mass index in long standing rheumatoid arthritis: relation to RA disease activity and functional indices |
| title_full_unstemmed | Low body mass index in long standing rheumatoid arthritis: relation to RA disease activity and functional indices |
| title_short | Low body mass index in long standing rheumatoid arthritis: relation to RA disease activity and functional indices |
| title_sort | low body mass index in long standing rheumatoid arthritis relation to ra disease activity and functional indices |
| topic | Rheumatoid arthritis Body mass index DAS28 Radiological erosions. |
| url | https://www.reumatismo.org/index.php/reuma/article/view/999 |
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