Activity of fibroblast-like synoviocytes in rheumatoid arthritis was impaired by dickkopf-1 targeting siRNA

Activity of fibroblast-like synoviocytes in rheumatoid arthritis was impaired by dickkopf-1 targeting siRNA

Abstract. Background. Fibroblast-like synoviocytes (FLSs), resident mesenchymal cells of synovial joints, play an important role in the pathogenesis of rheumatoid arthritis (RA). Dickkopf-1 (DKK-1) has been proposed to be a master regulator of bone remodeling in inflammatory arthritis. Here, potenti...

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Bibliographic Details
Main Authors:	Yan-Ying Liu, Shi-Yao Wang, Ying-Ni Li, Wen-Jie Bian, Lin-Qi Zhang, Yu-Hui Li, Li Long, Xia Liu, Xue-Wu Zhang, Zhan-Guo Li, Li-Shao Guo
Format:	Article
Language:	English
Published:	Wolters Kluwer 2020-03-01
Series:	Chinese Medical Journal
Online Access:	http://journals.lww.com/10.1097/CM9.0000000000000697

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