Rosa Damascena mediated ZnO-Red Ochre nanocomposite for the electrochemical determination of 5-Fluorouracil
In this study, ZnO-Red Ochre nanocomposite was green synthesized by Rosa Damascena (RD) extract (RDZRONCs). Proton Induced X-ray Emission microanalysis (Micro-PIXE) and X-ray diffraction (XRD) pattern confirmed the presence of hematite (Fe2O3), and quartz (SiO2) mineral phases in the Red Ochre (RO)...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-04-01
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| Series: | Arabian Journal of Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535223000473 |
| _version_ | 1811159969370734592 |
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| author | Javad Ebrahimian Maryam Khayatkashani Nasrin Soltani Halah T. Mohammed Nahid Tavakkoli Mina Jafari Masoud Salavati-Niasari |
| author_facet | Javad Ebrahimian Maryam Khayatkashani Nasrin Soltani Halah T. Mohammed Nahid Tavakkoli Mina Jafari Masoud Salavati-Niasari |
| author_sort | Javad Ebrahimian |
| collection | DOAJ |
| description | In this study, ZnO-Red Ochre nanocomposite was green synthesized by Rosa Damascena (RD) extract (RDZRONCs). Proton Induced X-ray Emission microanalysis (Micro-PIXE) and X-ray diffraction (XRD) pattern confirmed the presence of hematite (Fe2O3), and quartz (SiO2) mineral phases in the Red Ochre (RO) nanoclay. In addition, the XRD pattern shows the ZnO, ZnFe2O4, SiO2, Fe2O3, and Si phases in the RDZRONCs that were green synthesized with natural RD extract and RO. The RDZRONCs were used to modify the carbon paste electrode (CPE) for the electrochemical determination of the anticancer drug 5-fluorouracil (5-FU). Cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) techniques were employed to investigate the surface behavior of modified CPE (RDZRONCs/CPE). The electrochemical behavior of 5-FU at the RDZRONCs/CPE was exanimated by CV, differential pulse voltammetry (DPV), chronoamperometry (CA), and chronocoulometry (CC). Based on the DPV technique, a linear relationship between peak current and concentration of 5-FU was obtained in the dynamic range of 0.05–140.0 μM and with a detection limit equal to 0.0016 μM. The selectivity of RDZRONCs/CPE for 5-FU was studied in the presence of different inorganic and organic species. Also, the content of 5-FU was measured in real samples by RDZRONCs/CPE. |
| first_indexed | 2024-04-10T05:49:44Z |
| format | Article |
| id | doaj.art-6c0f41584888493a86e5a34fd1d1fd1f |
| institution | Directory Open Access Journal |
| issn | 1878-5352 |
| language | English |
| last_indexed | 2024-04-10T05:49:44Z |
| publishDate | 2023-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Arabian Journal of Chemistry |
| spelling | doaj.art-6c0f41584888493a86e5a34fd1d1fd1f2023-03-05T04:23:53ZengElsevierArabian Journal of Chemistry1878-53522023-04-01164104586Rosa Damascena mediated ZnO-Red Ochre nanocomposite for the electrochemical determination of 5-FluorouracilJavad Ebrahimian0Maryam Khayatkashani1Nasrin Soltani2Halah T. Mohammed3Nahid Tavakkoli4Mina Jafari5Masoud Salavati-Niasari6Alumni Association of Sharif University of Technology, 11365-11155 Tehran, IranAdvanced Medical Pharma (AMP-Biotec), Biopharmaceutical Innovation Centre, Via Cortenocera, 82030, San Salvatore Telesino, BN, Italy; Nutringredientes Research Center, Federal Institute of Education, Science and Technology (IFCE), BrazilDepartment of Chemistry, Payame Noor University, P.O. Box 19395-4697, Tehran, Iran; Corresponding authors.Anesthesia Techniques Department, Al-Mustaqbal University College, Babylon, IraqDepartment of Chemistry, Payame Noor University, P.O. Box 19395-4697, Tehran, IranDepartment of Chemistry, Payame Noor University, P.O. Box 19395-4697, Tehran, IranInstitute of Nano Science and Nano Technology, University of Kashan, Kashan 87317-51167, Iran; Corresponding authors.In this study, ZnO-Red Ochre nanocomposite was green synthesized by Rosa Damascena (RD) extract (RDZRONCs). Proton Induced X-ray Emission microanalysis (Micro-PIXE) and X-ray diffraction (XRD) pattern confirmed the presence of hematite (Fe2O3), and quartz (SiO2) mineral phases in the Red Ochre (RO) nanoclay. In addition, the XRD pattern shows the ZnO, ZnFe2O4, SiO2, Fe2O3, and Si phases in the RDZRONCs that were green synthesized with natural RD extract and RO. The RDZRONCs were used to modify the carbon paste electrode (CPE) for the electrochemical determination of the anticancer drug 5-fluorouracil (5-FU). Cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) techniques were employed to investigate the surface behavior of modified CPE (RDZRONCs/CPE). The electrochemical behavior of 5-FU at the RDZRONCs/CPE was exanimated by CV, differential pulse voltammetry (DPV), chronoamperometry (CA), and chronocoulometry (CC). Based on the DPV technique, a linear relationship between peak current and concentration of 5-FU was obtained in the dynamic range of 0.05–140.0 μM and with a detection limit equal to 0.0016 μM. The selectivity of RDZRONCs/CPE for 5-FU was studied in the presence of different inorganic and organic species. Also, the content of 5-FU was measured in real samples by RDZRONCs/CPE.http://www.sciencedirect.com/science/article/pii/S1878535223000473Green synthesisRosa DamascenaZnO-Red Ochre NanostructuresNanoclay5-FluorouracilElectrochemical sensor |
| spellingShingle | Javad Ebrahimian Maryam Khayatkashani Nasrin Soltani Halah T. Mohammed Nahid Tavakkoli Mina Jafari Masoud Salavati-Niasari Rosa Damascena mediated ZnO-Red Ochre nanocomposite for the electrochemical determination of 5-Fluorouracil Arabian Journal of Chemistry Green synthesis Rosa Damascena ZnO-Red Ochre Nanostructures Nanoclay 5-Fluorouracil Electrochemical sensor |
| title | Rosa Damascena mediated ZnO-Red Ochre nanocomposite for the electrochemical determination of 5-Fluorouracil |
| title_full | Rosa Damascena mediated ZnO-Red Ochre nanocomposite for the electrochemical determination of 5-Fluorouracil |
| title_fullStr | Rosa Damascena mediated ZnO-Red Ochre nanocomposite for the electrochemical determination of 5-Fluorouracil |
| title_full_unstemmed | Rosa Damascena mediated ZnO-Red Ochre nanocomposite for the electrochemical determination of 5-Fluorouracil |
| title_short | Rosa Damascena mediated ZnO-Red Ochre nanocomposite for the electrochemical determination of 5-Fluorouracil |
| title_sort | rosa damascena mediated zno red ochre nanocomposite for the electrochemical determination of 5 fluorouracil |
| topic | Green synthesis Rosa Damascena ZnO-Red Ochre Nanostructures Nanoclay 5-Fluorouracil Electrochemical sensor |
| url | http://www.sciencedirect.com/science/article/pii/S1878535223000473 |
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