An Overview of Micro- and Nanoemulsions as Vehicles for Essential Oils: Formulation, Preparation and Stability

The interest around essential oils is constantly increasing thanks to their biological properties exploitable in several fields, from pharmaceuticals to food and agriculture. However, their widespread use and marketing are still restricted due to their poor physico-chemical properties; i.e., high vo...

Full description

Bibliographic Details
Main Authors: Lucia Pavoni, Diego Romano Perinelli, Giulia Bonacucina, Marco Cespi, Giovanni Filippo Palmieri
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/10/1/135
_version_ 1818940909843120128
author Lucia Pavoni
Diego Romano Perinelli
Giulia Bonacucina
Marco Cespi
Giovanni Filippo Palmieri
author_facet Lucia Pavoni
Diego Romano Perinelli
Giulia Bonacucina
Marco Cespi
Giovanni Filippo Palmieri
author_sort Lucia Pavoni
collection DOAJ
description The interest around essential oils is constantly increasing thanks to their biological properties exploitable in several fields, from pharmaceuticals to food and agriculture. However, their widespread use and marketing are still restricted due to their poor physico-chemical properties; i.e., high volatility, thermal decomposition, low water solubility, and stability issues. At the moment, the most suitable approach to overcome such limitations is based on the development of proper formulation strategies. One of the approaches suggested to achieve this goal is the so-called encapsulation process through the preparation of aqueous nano-dispersions. Among them, micro- and nanoemulsions are the most studied thanks to the ease of formulation, handling and to their manufacturing costs. In this direction, this review intends to offer an overview of the formulation, preparation and stability parameters of micro- and nanoemulsions. Specifically, recent literature has been examined in order to define the most common practices adopted (materials and fabrication methods), highlighting their suitability and effectiveness. Finally, relevant points related to formulations, such as optimization, characterization, stability and safety, not deeply studied or clarified yet, were discussed.
first_indexed 2024-12-20T06:47:08Z
format Article
id doaj.art-6c13cb6cce6c4f4e9077fc6a47f8ced9
institution Directory Open Access Journal
issn 2079-4991
language English
last_indexed 2024-12-20T06:47:08Z
publishDate 2020-01-01
publisher MDPI AG
record_format Article
series Nanomaterials
spelling doaj.art-6c13cb6cce6c4f4e9077fc6a47f8ced92022-12-21T19:49:40ZengMDPI AGNanomaterials2079-49912020-01-0110113510.3390/nano10010135nano10010135An Overview of Micro- and Nanoemulsions as Vehicles for Essential Oils: Formulation, Preparation and StabilityLucia Pavoni0Diego Romano Perinelli1Giulia Bonacucina2Marco Cespi3Giovanni Filippo Palmieri4School of Pharmacy, University of Camerino, 62032 Camerino, ItalySchool of Pharmacy, University of Camerino, 62032 Camerino, ItalySchool of Pharmacy, University of Camerino, 62032 Camerino, ItalySchool of Pharmacy, University of Camerino, 62032 Camerino, ItalySchool of Pharmacy, University of Camerino, 62032 Camerino, ItalyThe interest around essential oils is constantly increasing thanks to their biological properties exploitable in several fields, from pharmaceuticals to food and agriculture. However, their widespread use and marketing are still restricted due to their poor physico-chemical properties; i.e., high volatility, thermal decomposition, low water solubility, and stability issues. At the moment, the most suitable approach to overcome such limitations is based on the development of proper formulation strategies. One of the approaches suggested to achieve this goal is the so-called encapsulation process through the preparation of aqueous nano-dispersions. Among them, micro- and nanoemulsions are the most studied thanks to the ease of formulation, handling and to their manufacturing costs. In this direction, this review intends to offer an overview of the formulation, preparation and stability parameters of micro- and nanoemulsions. Specifically, recent literature has been examined in order to define the most common practices adopted (materials and fabrication methods), highlighting their suitability and effectiveness. Finally, relevant points related to formulations, such as optimization, characterization, stability and safety, not deeply studied or clarified yet, were discussed.https://www.mdpi.com/2079-4991/10/1/135essential oilnanoemulsionmicroemulsionsurfactantco-surfactant
spellingShingle Lucia Pavoni
Diego Romano Perinelli
Giulia Bonacucina
Marco Cespi
Giovanni Filippo Palmieri
An Overview of Micro- and Nanoemulsions as Vehicles for Essential Oils: Formulation, Preparation and Stability
Nanomaterials
essential oil
nanoemulsion
microemulsion
surfactant
co-surfactant
title An Overview of Micro- and Nanoemulsions as Vehicles for Essential Oils: Formulation, Preparation and Stability
title_full An Overview of Micro- and Nanoemulsions as Vehicles for Essential Oils: Formulation, Preparation and Stability
title_fullStr An Overview of Micro- and Nanoemulsions as Vehicles for Essential Oils: Formulation, Preparation and Stability
title_full_unstemmed An Overview of Micro- and Nanoemulsions as Vehicles for Essential Oils: Formulation, Preparation and Stability
title_short An Overview of Micro- and Nanoemulsions as Vehicles for Essential Oils: Formulation, Preparation and Stability
title_sort overview of micro and nanoemulsions as vehicles for essential oils formulation preparation and stability
topic essential oil
nanoemulsion
microemulsion
surfactant
co-surfactant
url https://www.mdpi.com/2079-4991/10/1/135
work_keys_str_mv AT luciapavoni anoverviewofmicroandnanoemulsionsasvehiclesforessentialoilsformulationpreparationandstability
AT diegoromanoperinelli anoverviewofmicroandnanoemulsionsasvehiclesforessentialoilsformulationpreparationandstability
AT giuliabonacucina anoverviewofmicroandnanoemulsionsasvehiclesforessentialoilsformulationpreparationandstability
AT marcocespi anoverviewofmicroandnanoemulsionsasvehiclesforessentialoilsformulationpreparationandstability
AT giovannifilippopalmieri anoverviewofmicroandnanoemulsionsasvehiclesforessentialoilsformulationpreparationandstability
AT luciapavoni overviewofmicroandnanoemulsionsasvehiclesforessentialoilsformulationpreparationandstability
AT diegoromanoperinelli overviewofmicroandnanoemulsionsasvehiclesforessentialoilsformulationpreparationandstability
AT giuliabonacucina overviewofmicroandnanoemulsionsasvehiclesforessentialoilsformulationpreparationandstability
AT marcocespi overviewofmicroandnanoemulsionsasvehiclesforessentialoilsformulationpreparationandstability
AT giovannifilippopalmieri overviewofmicroandnanoemulsionsasvehiclesforessentialoilsformulationpreparationandstability