Assessment of weight and height of patients with primary immunodeficiency disorders and group of children with recurrent respiratory tract infections
Abstract Background Primary immunodeficiences (PIDs) are a group of chronic, serious disorders in which the immune response is insufficient. In consequence, it leads to an increased susceptibility to infections. Up to date, there are about 350 different disorders classified in that group. There are...
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| Format: | Article |
| Language: | English |
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BMC
2020-07-01
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| Series: | BMC Immunology |
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| Online Access: | http://link.springer.com/article/10.1186/s12865-020-00372-x |
| _version_ | 1818873076905934848 |
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| author | Karolina Pieniawska-Śmiech Kamil Bar Mateusz Babicki Karol Śmiech Aleksandra Lewandowicz-Uszyńska |
| author_facet | Karolina Pieniawska-Śmiech Kamil Bar Mateusz Babicki Karol Śmiech Aleksandra Lewandowicz-Uszyńska |
| author_sort | Karolina Pieniawska-Śmiech |
| collection | DOAJ |
| description | Abstract Background Primary immunodeficiences (PIDs) are a group of chronic, serious disorders in which the immune response is insufficient. In consequence, it leads to an increased susceptibility to infections. Up to date, there are about 350 different disorders classified in that group. There are also patients suffering from recurrent respiratory tract infections (RRTI), however that group doesn’t present any abnormalities in terms of conducted immunological tests. Many factors, including medical, can have an impact on physical development of a child. Data such as birth weight and length, also weight, height, BMI during admission to the hospital were collected from 195 patients’ medical histories from their hospitalization at Clinical Immunology and Paediatrics Ward of J. Gromkowski Hospital in Wrocław. Investigated groups included patients with PIDs, RRTI and a control group of healthy children. Our purpose was to evaluate the physical growth of children with PID and children with RRTI by assessment of their height and weight. All of parameters were evaluated using centile charts, suitable best for the Polish population. Results The lowest mean birth weight and height was found among the PIDs patients group. Children with PIDs during hospitalization had statistically relevant lower mean weight than the control group and almost 18% of them had their height situated below 3rd percentile. The statistically relevant differences have been found between them and RRTI group in terms of weight, height and nutritional status. The statistically significant difference was detected between the nutritional status of PID and control group. Conclusions There is a higher percentage of PID patients with physical growth abnormalities in comparison to healthy children. Our findings indicate a need for further investigation of immune system irregularities and their influence on physical growth of children. |
| first_indexed | 2024-12-19T12:48:58Z |
| format | Article |
| id | doaj.art-6c17142e2ce54c078f838d3ebcd50440 |
| institution | Directory Open Access Journal |
| issn | 1471-2172 |
| language | English |
| last_indexed | 2024-12-19T12:48:58Z |
| publishDate | 2020-07-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Immunology |
| spelling | doaj.art-6c17142e2ce54c078f838d3ebcd504402022-12-21T20:20:38ZengBMCBMC Immunology1471-21722020-07-0121111010.1186/s12865-020-00372-xAssessment of weight and height of patients with primary immunodeficiency disorders and group of children with recurrent respiratory tract infectionsKarolina Pieniawska-Śmiech0Kamil Bar1Mateusz Babicki2Karol Śmiech3Aleksandra Lewandowicz-Uszyńska4Student Research Circle at 3rd Department and Clinic of Paediatrics, Immunology and Rheumatology of Developmental Age, Wroclaw Medical UniversityStudent Research Circle at 3rd Department and Clinic of Paediatrics, Immunology and Rheumatology of Developmental Age, Wroclaw Medical UniversityStudent Research Circle at 3rd Department and Clinic of Paediatrics, Immunology and Rheumatology of Developmental Age, Wroclaw Medical UniversityStudent Research Circle at 3rd Department and Clinic of Paediatrics, Immunology and Rheumatology of Developmental Age, Wroclaw Medical UniversityJ.Gromkowski Regional Specialist HospitalAbstract Background Primary immunodeficiences (PIDs) are a group of chronic, serious disorders in which the immune response is insufficient. In consequence, it leads to an increased susceptibility to infections. Up to date, there are about 350 different disorders classified in that group. There are also patients suffering from recurrent respiratory tract infections (RRTI), however that group doesn’t present any abnormalities in terms of conducted immunological tests. Many factors, including medical, can have an impact on physical development of a child. Data such as birth weight and length, also weight, height, BMI during admission to the hospital were collected from 195 patients’ medical histories from their hospitalization at Clinical Immunology and Paediatrics Ward of J. Gromkowski Hospital in Wrocław. Investigated groups included patients with PIDs, RRTI and a control group of healthy children. Our purpose was to evaluate the physical growth of children with PID and children with RRTI by assessment of their height and weight. All of parameters were evaluated using centile charts, suitable best for the Polish population. Results The lowest mean birth weight and height was found among the PIDs patients group. Children with PIDs during hospitalization had statistically relevant lower mean weight than the control group and almost 18% of them had their height situated below 3rd percentile. The statistically relevant differences have been found between them and RRTI group in terms of weight, height and nutritional status. The statistically significant difference was detected between the nutritional status of PID and control group. Conclusions There is a higher percentage of PID patients with physical growth abnormalities in comparison to healthy children. Our findings indicate a need for further investigation of immune system irregularities and their influence on physical growth of children.http://link.springer.com/article/10.1186/s12865-020-00372-xPrimary immunodeficiencyRecurrent respiratory tract infectionsPhysical growthGrowth assessment |
| spellingShingle | Karolina Pieniawska-Śmiech Kamil Bar Mateusz Babicki Karol Śmiech Aleksandra Lewandowicz-Uszyńska Assessment of weight and height of patients with primary immunodeficiency disorders and group of children with recurrent respiratory tract infections BMC Immunology Primary immunodeficiency Recurrent respiratory tract infections Physical growth Growth assessment |
| title | Assessment of weight and height of patients with primary immunodeficiency disorders and group of children with recurrent respiratory tract infections |
| title_full | Assessment of weight and height of patients with primary immunodeficiency disorders and group of children with recurrent respiratory tract infections |
| title_fullStr | Assessment of weight and height of patients with primary immunodeficiency disorders and group of children with recurrent respiratory tract infections |
| title_full_unstemmed | Assessment of weight and height of patients with primary immunodeficiency disorders and group of children with recurrent respiratory tract infections |
| title_short | Assessment of weight and height of patients with primary immunodeficiency disorders and group of children with recurrent respiratory tract infections |
| title_sort | assessment of weight and height of patients with primary immunodeficiency disorders and group of children with recurrent respiratory tract infections |
| topic | Primary immunodeficiency Recurrent respiratory tract infections Physical growth Growth assessment |
| url | http://link.springer.com/article/10.1186/s12865-020-00372-x |
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