Placebo and nocebo phenomena from the perspective of evidence based and person centered medicine
Introduction: Placebo and nocebo phenomena in pharmacology are very important, but controversial issues from the perspective of evidence-based medicine (EBM) in many ways. Topic: Glorification and vilification of placebo controlled studies are the two opposite sides of the prevailing misunderstandin...
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| Format: | Article |
| Language: | English |
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Srpsko lekarsko drustvo
2017-01-01
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| Series: | Hospital Pharmacology |
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| Online Access: | http://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2017/2334-94921702512J.pdf |
| Summary: | Introduction: Placebo and nocebo phenomena in pharmacology are very important, but controversial issues from the perspective of evidence-based medicine (EBM) in many ways. Topic: Glorification and vilification of placebo controlled studies are the two opposite sides of the prevailing misunderstanding placebo and nocebo phenomena in medicine and pharmacology. This misunderstanding is an essential component of the pseudoscientific evaluation and evidence-based medicine. The using of placebo and avoidance of nocebo responses have been recommended as promising additional clinical strategies. The aim and purpose of this paper is to give a transdisciplinary and integrative overview of the placebo and nocebo from the perspective of person-centered medicine and also to provide some practical tips on how to increase placebo and decrease nocebo response in clinical practice. Conclusions: Conflicting data from clinical trials and misunderstanding of placebo and nocebo phenomena are essential components of the contamination and confusion regarding evidence-based medicine. Person-centered clinical pharmacology is partly about taking advantage of placebo and avoiding of nocebo phenomena in a clinical setting as additive effects to improve the effectiveness of the standard medication. |
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| ISSN: | 2334-9492 2334-9492 |