Placebo and nocebo phenomena from the perspective of evidence based and person centered medicine

Introduction: Placebo and nocebo phenomena in pharmacology are very important, but controversial issues from the perspective of evidence-based medicine (EBM) in many ways. Topic: Glorification and vilification of placebo controlled studies are the two opposite sides of the prevailing misunderstandin...

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Main Author: Jakovljević Miro I.
Format: Article
Language:English
Published: Srpsko lekarsko drustvo 2017-01-01
Series:Hospital Pharmacology
Subjects:
Online Access:http://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2017/2334-94921702512J.pdf
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author Jakovljević Miro I.
author_facet Jakovljević Miro I.
author_sort Jakovljević Miro I.
collection DOAJ
description Introduction: Placebo and nocebo phenomena in pharmacology are very important, but controversial issues from the perspective of evidence-based medicine (EBM) in many ways. Topic: Glorification and vilification of placebo controlled studies are the two opposite sides of the prevailing misunderstanding placebo and nocebo phenomena in medicine and pharmacology. This misunderstanding is an essential component of the pseudoscientific evaluation and evidence-based medicine. The using of placebo and avoidance of nocebo responses have been recommended as promising additional clinical strategies. The aim and purpose of this paper is to give a transdisciplinary and integrative overview of the placebo and nocebo from the perspective of person-centered medicine and also to provide some practical tips on how to increase placebo and decrease nocebo response in clinical practice. Conclusions: Conflicting data from clinical trials and misunderstanding of placebo and nocebo phenomena are essential components of the contamination and confusion regarding evidence-based medicine. Person-centered clinical pharmacology is partly about taking advantage of placebo and avoiding of nocebo phenomena in a clinical setting as additive effects to improve the effectiveness of the standard medication.
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spelling doaj.art-6c1866eb89bc477496348ae83ff4c9ac2022-12-22T00:43:15ZengSrpsko lekarsko drustvoHospital Pharmacology2334-94922334-94922017-01-014251252010.5937/hpimj1702512J2334-94921702512JPlacebo and nocebo phenomena from the perspective of evidence based and person centered medicineJakovljević Miro I.0Department of Psychiatry, School of Medicine, University of Zagreb in Clinical Hospital Centre Zagreb, Zagreb, CroatiaIntroduction: Placebo and nocebo phenomena in pharmacology are very important, but controversial issues from the perspective of evidence-based medicine (EBM) in many ways. Topic: Glorification and vilification of placebo controlled studies are the two opposite sides of the prevailing misunderstanding placebo and nocebo phenomena in medicine and pharmacology. This misunderstanding is an essential component of the pseudoscientific evaluation and evidence-based medicine. The using of placebo and avoidance of nocebo responses have been recommended as promising additional clinical strategies. The aim and purpose of this paper is to give a transdisciplinary and integrative overview of the placebo and nocebo from the perspective of person-centered medicine and also to provide some practical tips on how to increase placebo and decrease nocebo response in clinical practice. Conclusions: Conflicting data from clinical trials and misunderstanding of placebo and nocebo phenomena are essential components of the contamination and confusion regarding evidence-based medicine. Person-centered clinical pharmacology is partly about taking advantage of placebo and avoiding of nocebo phenomena in a clinical setting as additive effects to improve the effectiveness of the standard medication.http://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2017/2334-94921702512J.pdfplacebonoceboevidence-basedsalutogenesisresilienceperson centeredmedicinepersonalizedclinical pharmacology
spellingShingle Jakovljević Miro I.
Placebo and nocebo phenomena from the perspective of evidence based and person centered medicine
Hospital Pharmacology
placebo
nocebo
evidence-based
salutogenesis
resilience
person centered
medicine
personalized
clinical pharmacology
title Placebo and nocebo phenomena from the perspective of evidence based and person centered medicine
title_full Placebo and nocebo phenomena from the perspective of evidence based and person centered medicine
title_fullStr Placebo and nocebo phenomena from the perspective of evidence based and person centered medicine
title_full_unstemmed Placebo and nocebo phenomena from the perspective of evidence based and person centered medicine
title_short Placebo and nocebo phenomena from the perspective of evidence based and person centered medicine
title_sort placebo and nocebo phenomena from the perspective of evidence based and person centered medicine
topic placebo
nocebo
evidence-based
salutogenesis
resilience
person centered
medicine
personalized
clinical pharmacology
url http://scindeks-clanci.ceon.rs/data/pdf/2334-9492/2017/2334-94921702512J.pdf
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