Calcium, Bioenergetics, and Parkinson’s Disease

Calcium, Bioenergetics, and Parkinson’s Disease

Degeneration of substantia nigra (SN) dopaminergic (DAergic) neurons is responsible for the core motor deficits of Parkinson’s disease (PD). These neurons are autonomous pacemakers that have large cytosolic Ca<sup>2+</sup> oscillations that have been linked to basal mitochondrial oxidant...

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Bibliographic Details
Main Authors:	Enrico Zampese, D. James Surmeier
Format:	Article
Language:	English
Published:	MDPI AG 2020-09-01
Series:	Cells
Subjects:	Parkinson’s disease substantia nigra dopaminergic neurons Ca<sup>2+</sup> mitochondria bioenergetics
Online Access:	https://www.mdpi.com/2073-4409/9/9/2045

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