Clinicopathological Correlation of Abdominal Lesions for Assessment of Diagnostic Efficacy of Minimally Invasive Techniques

Introduction: Evaluation of abdominal masses may pose difficulty in surgical practice. Distinction between malignant, benign and inflammatory lesions is vital for patient’s management. Hence, use of minimally invasive techniques under radiological guidance with pathological correlation is gaini...

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Main Authors: Shiwangi Garg, Rani Bansal, Shweta Grover, Sameer Verma, Mamta Gupta, Shefali Verma
Format: Article
Language:English
Published: JCDR Research and Publications Pvt. Ltd. 2016-10-01
Series:National Journal of Laboratory Medicine
Subjects:
Online Access:http://www.njlm.net/articles/PDF/2160/20690_F(P)_PF1(VsuGH)_PFA(GH)_PF2(VsuGH).pdf
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author Shiwangi Garg
Rani Bansal
Shweta Grover
Sameer Verma
Mamta Gupta
Shefali Verma
author_facet Shiwangi Garg
Rani Bansal
Shweta Grover
Sameer Verma
Mamta Gupta
Shefali Verma
author_sort Shiwangi Garg
collection DOAJ
description Introduction: Evaluation of abdominal masses may pose difficulty in surgical practice. Distinction between malignant, benign and inflammatory lesions is vital for patient’s management. Hence, use of minimally invasive techniques under radiological guidance with pathological correlation is gaining popularity as a means of diagnosing abdominal lesions. Aim: To assess the pathological spectrum of abdominal lesions and to determine the diagnostic efficacy of minimally invasive techniques. Materials and Methods: Total 102 consecutive patients with clinically or radiologically diagnosed abdominal lesions excluding pelvic masses were evaluated by minimal invasive techniques like direct or guided Fine Needle Aspiration Cytology (FNAC) by 22-24 gauge needle and Tru-cut biopsy (TCB) by Geotex automated gun with 18 gauge needle. Statistical analysis was done by 2x2 contingency table by comparing the test diagnosis with the gold standard diagnosis. Results: Majority (n=32) of lesions were from liver (31.3%) among which metastatic carcinomas were most common followed by primary, next in frequency belonged to gall bladder 17 (16.6%). Among all abdominal lesions, maximum cases were malignant followed by benign and inflammatory. sensitivity, specificity, positive predictive value, negative predictive value and overall diagnostic accuracy of FNAC and TCB were 100% each and 90%, 100%, 100%, 83.3%, 93.3% respectively. No serious complications were observed after these procedures. Conclusion: Minimally invasive techniques are simple, safe and efficient procedures for making an accurate diagnosis in abdominal lesions and helps in choosing the appropriate management.
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spelling doaj.art-6c22918a0c1942998add8b3f62df6e422022-12-21T17:18:06ZengJCDR Research and Publications Pvt. Ltd.National Journal of Laboratory Medicine2277-85512455-68822016-10-0154PO01PO0710.7860/NJLM/2016/20690.2160Clinicopathological Correlation of Abdominal Lesions for Assessment of Diagnostic Efficacy of Minimally Invasive TechniquesShiwangi Garg0Rani Bansal1Shweta Grover2Sameer Verma3Mamta Gupta4Shefali Verma5Post Graduate, Department of Pathology, Subharti Medical College, Meerut, UP, India.Professor and Head, Department of Pathology, Subharti Medical College, Meerut, UP, India.Associate Professor, Department of Pathology, Subharti Medical College, Meerut, UP, India.Professor, Department of Radiology, Subharti Medical College, Meerut, UP, India.Associate Professor, Department of Pathology, Subharti Medical College, Meerut, UP, India.Post Graduate, Department of Pathology, Subharti Medical College, Meerut, UP, India.Introduction: Evaluation of abdominal masses may pose difficulty in surgical practice. Distinction between malignant, benign and inflammatory lesions is vital for patient’s management. Hence, use of minimally invasive techniques under radiological guidance with pathological correlation is gaining popularity as a means of diagnosing abdominal lesions. Aim: To assess the pathological spectrum of abdominal lesions and to determine the diagnostic efficacy of minimally invasive techniques. Materials and Methods: Total 102 consecutive patients with clinically or radiologically diagnosed abdominal lesions excluding pelvic masses were evaluated by minimal invasive techniques like direct or guided Fine Needle Aspiration Cytology (FNAC) by 22-24 gauge needle and Tru-cut biopsy (TCB) by Geotex automated gun with 18 gauge needle. Statistical analysis was done by 2x2 contingency table by comparing the test diagnosis with the gold standard diagnosis. Results: Majority (n=32) of lesions were from liver (31.3%) among which metastatic carcinomas were most common followed by primary, next in frequency belonged to gall bladder 17 (16.6%). Among all abdominal lesions, maximum cases were malignant followed by benign and inflammatory. sensitivity, specificity, positive predictive value, negative predictive value and overall diagnostic accuracy of FNAC and TCB were 100% each and 90%, 100%, 100%, 83.3%, 93.3% respectively. No serious complications were observed after these procedures. Conclusion: Minimally invasive techniques are simple, safe and efficient procedures for making an accurate diagnosis in abdominal lesions and helps in choosing the appropriate management.http://www.njlm.net/articles/PDF/2160/20690_F(P)_PF1(VsuGH)_PFA(GH)_PF2(VsuGH).pdffine needle aspiration cytology (fnac)radiologically guidedspace occupying lesions (sol)tru-cut biopsy (tcb)
spellingShingle Shiwangi Garg
Rani Bansal
Shweta Grover
Sameer Verma
Mamta Gupta
Shefali Verma
Clinicopathological Correlation of Abdominal Lesions for Assessment of Diagnostic Efficacy of Minimally Invasive Techniques
National Journal of Laboratory Medicine
fine needle aspiration cytology (fnac)
radiologically guided
space occupying lesions (sol)
tru-cut biopsy (tcb)
title Clinicopathological Correlation of Abdominal Lesions for Assessment of Diagnostic Efficacy of Minimally Invasive Techniques
title_full Clinicopathological Correlation of Abdominal Lesions for Assessment of Diagnostic Efficacy of Minimally Invasive Techniques
title_fullStr Clinicopathological Correlation of Abdominal Lesions for Assessment of Diagnostic Efficacy of Minimally Invasive Techniques
title_full_unstemmed Clinicopathological Correlation of Abdominal Lesions for Assessment of Diagnostic Efficacy of Minimally Invasive Techniques
title_short Clinicopathological Correlation of Abdominal Lesions for Assessment of Diagnostic Efficacy of Minimally Invasive Techniques
title_sort clinicopathological correlation of abdominal lesions for assessment of diagnostic efficacy of minimally invasive techniques
topic fine needle aspiration cytology (fnac)
radiologically guided
space occupying lesions (sol)
tru-cut biopsy (tcb)
url http://www.njlm.net/articles/PDF/2160/20690_F(P)_PF1(VsuGH)_PFA(GH)_PF2(VsuGH).pdf
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