Pharmacokinetics of Nafamostat, a Potent Serine Protease Inhibitor, by a Novel LC-MS/MS Analysis

Pharmacokinetics of Nafamostat, a Potent Serine Protease Inhibitor, by a Novel LC-MS/MS Analysis

Nafamostat, a synthetic serine protease inhibitor, has been used for the treatment of inflammatory diseases such as pancreatitis. Recently, an increasing number of studies have shown the promising antiviral effects of nafamostat for the treatment of coronavirus disease-19 (COVID-19). This study aime...

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Bibliographic Details
Main Authors: Hyeon Seok Oh, Taehyung Kim, Dong-Hyeon Gu, Tae Suk Lee, Tae Hwan Kim, Soyoung Shin, Beom Soo Shin
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Molecules
Subjects:
nafamostat
COVID-19
LC-MS/MS
pharmacokinetics
bioavailability
Online Access:https://www.mdpi.com/1420-3049/27/6/1881

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