The Parkinson’s Disease Progression Neuroimaging Initiative
The Parkinson’s Disease Progressive Neuroimaging Initiative (PDPNI) is a longitudinal observational clinical study. In PDPNI, the clinical and imaging data of patients diagnosed with Parkinsonian syndromes and Idiopathic rapid eye movement sleep behavior disorder (RBD) were longitudinally followed e...
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2021-01-01
|
| Series: | Behavioural Neurology |
| Online Access: | http://dx.doi.org/10.1155/2021/2230196 |
| _version_ | 1798034243737092096 |
|---|---|
| author | Shiyi Zhu Zizhao Ju Ping Wu Fengtao Liu Jingjie Ge Huiwei Zhang Jiaying Lu Ling Li Min Wang Jiehui Jiang Jian Wang Chuantao Zuo |
| author_facet | Shiyi Zhu Zizhao Ju Ping Wu Fengtao Liu Jingjie Ge Huiwei Zhang Jiaying Lu Ling Li Min Wang Jiehui Jiang Jian Wang Chuantao Zuo |
| author_sort | Shiyi Zhu |
| collection | DOAJ |
| description | The Parkinson’s Disease Progressive Neuroimaging Initiative (PDPNI) is a longitudinal observational clinical study. In PDPNI, the clinical and imaging data of patients diagnosed with Parkinsonian syndromes and Idiopathic rapid eye movement sleep behavior disorder (RBD) were longitudinally followed every two years, aiming to identify progression biomarkers of Parkinsonian syndromes through functional imaging modalities including FDG-PET, DAT-PET imaging, ASL MRI, and fMRI, as well as the treatment conditions, clinical symptoms, and clinical assessment results of patients. From February 2012 to March 2019, 224 subjects (including 48 healthy subjects and 176 patients with confirmed PDS) have been enrolled in PDPNI. The detailed clinical information and clinical assessment scores of all subjects were collected by neurologists from Huashan Hospital, Fudan University. All subjects enrolled in PDPNI were scanned with 18F-FDG PET, 11C-CFT PET, and MRI scan sequence. All data were collected in strict accordance with standardized data collection protocols. |
| first_indexed | 2024-04-11T20:41:40Z |
| format | Article |
| id | doaj.art-6c2661971008434bb563217d50f527e4 |
| institution | Directory Open Access Journal |
| issn | 1875-8584 |
| language | English |
| last_indexed | 2024-04-11T20:41:40Z |
| publishDate | 2021-01-01 |
| publisher | Hindawi Limited |
| record_format | Article |
| series | Behavioural Neurology |
| spelling | doaj.art-6c2661971008434bb563217d50f527e42022-12-22T04:04:11ZengHindawi LimitedBehavioural Neurology1875-85842021-01-01202110.1155/2021/2230196The Parkinson’s Disease Progression Neuroimaging InitiativeShiyi Zhu0Zizhao Ju1Ping Wu2Fengtao Liu3Jingjie Ge4Huiwei Zhang5Jiaying Lu6Ling Li7Min Wang8Jiehui Jiang9Jian Wang10Chuantao Zuo11School of Communication and Information EngineeringPET Center and National Research Center for Aging and Medicine & National Center for Neurological DisordersPET Center and National Research Center for Aging and Medicine & National Center for Neurological DisordersDepartment of Neurology and National Research Center for Aging and Medicine & National Center for Neurological DisordersPET Center and National Research Center for Aging and Medicine & National Center for Neurological DisordersPET Center and National Research Center for Aging and Medicine & National Center for Neurological DisordersPET Center and National Research Center for Aging and Medicine & National Center for Neurological DisordersPET Center and National Research Center for Aging and Medicine & National Center for Neurological DisordersSchool of Communication and Information EngineeringSchool of Life ScienceDepartment of Neurology and National Research Center for Aging and Medicine & National Center for Neurological DisordersPET Center and National Research Center for Aging and Medicine & National Center for Neurological DisordersThe Parkinson’s Disease Progressive Neuroimaging Initiative (PDPNI) is a longitudinal observational clinical study. In PDPNI, the clinical and imaging data of patients diagnosed with Parkinsonian syndromes and Idiopathic rapid eye movement sleep behavior disorder (RBD) were longitudinally followed every two years, aiming to identify progression biomarkers of Parkinsonian syndromes through functional imaging modalities including FDG-PET, DAT-PET imaging, ASL MRI, and fMRI, as well as the treatment conditions, clinical symptoms, and clinical assessment results of patients. From February 2012 to March 2019, 224 subjects (including 48 healthy subjects and 176 patients with confirmed PDS) have been enrolled in PDPNI. The detailed clinical information and clinical assessment scores of all subjects were collected by neurologists from Huashan Hospital, Fudan University. All subjects enrolled in PDPNI were scanned with 18F-FDG PET, 11C-CFT PET, and MRI scan sequence. All data were collected in strict accordance with standardized data collection protocols.http://dx.doi.org/10.1155/2021/2230196 |
| spellingShingle | Shiyi Zhu Zizhao Ju Ping Wu Fengtao Liu Jingjie Ge Huiwei Zhang Jiaying Lu Ling Li Min Wang Jiehui Jiang Jian Wang Chuantao Zuo The Parkinson’s Disease Progression Neuroimaging Initiative Behavioural Neurology |
| title | The Parkinson’s Disease Progression Neuroimaging Initiative |
| title_full | The Parkinson’s Disease Progression Neuroimaging Initiative |
| title_fullStr | The Parkinson’s Disease Progression Neuroimaging Initiative |
| title_full_unstemmed | The Parkinson’s Disease Progression Neuroimaging Initiative |
| title_short | The Parkinson’s Disease Progression Neuroimaging Initiative |
| title_sort | parkinson s disease progression neuroimaging initiative |
| url | http://dx.doi.org/10.1155/2021/2230196 |
| work_keys_str_mv | AT shiyizhu theparkinsonsdiseaseprogressionneuroimaginginitiative AT zizhaoju theparkinsonsdiseaseprogressionneuroimaginginitiative AT pingwu theparkinsonsdiseaseprogressionneuroimaginginitiative AT fengtaoliu theparkinsonsdiseaseprogressionneuroimaginginitiative AT jingjiege theparkinsonsdiseaseprogressionneuroimaginginitiative AT huiweizhang theparkinsonsdiseaseprogressionneuroimaginginitiative AT jiayinglu theparkinsonsdiseaseprogressionneuroimaginginitiative AT lingli theparkinsonsdiseaseprogressionneuroimaginginitiative AT minwang theparkinsonsdiseaseprogressionneuroimaginginitiative AT jiehuijiang theparkinsonsdiseaseprogressionneuroimaginginitiative AT jianwang theparkinsonsdiseaseprogressionneuroimaginginitiative AT chuantaozuo theparkinsonsdiseaseprogressionneuroimaginginitiative AT shiyizhu parkinsonsdiseaseprogressionneuroimaginginitiative AT zizhaoju parkinsonsdiseaseprogressionneuroimaginginitiative AT pingwu parkinsonsdiseaseprogressionneuroimaginginitiative AT fengtaoliu parkinsonsdiseaseprogressionneuroimaginginitiative AT jingjiege parkinsonsdiseaseprogressionneuroimaginginitiative AT huiweizhang parkinsonsdiseaseprogressionneuroimaginginitiative AT jiayinglu parkinsonsdiseaseprogressionneuroimaginginitiative AT lingli parkinsonsdiseaseprogressionneuroimaginginitiative AT minwang parkinsonsdiseaseprogressionneuroimaginginitiative AT jiehuijiang parkinsonsdiseaseprogressionneuroimaginginitiative AT jianwang parkinsonsdiseaseprogressionneuroimaginginitiative AT chuantaozuo parkinsonsdiseaseprogressionneuroimaginginitiative |