Reprogramming of profibrotic macrophages for treatment of bleomycin‐induced pulmonary fibrosis

Reprogramming of profibrotic macrophages for treatment of bleomycin‐induced pulmonary fibrosis

Abstract Fibrotic diseases cause organ failure that lead to ~45% of all deaths in the United States. Activated macrophages stimulate fibrosis by secreting cytokines that induce fibroblasts to synthesize collagen and extracellular matrix proteins. Although suppression of macrophage‐derived cytokine p...

Повний опис

Бібліографічні деталі
Автори: Fenghua Zhang, Ehab A Ayaub, Bingbing Wang, Estela Puchulu‐Campanella, Yen‐Hsing Li, Suraj U Hettiarachchi, Spencer D Lindeman, Qian Luo, Sasmita Rout, Madduri Srinivasarao, Abigail Cox, Konstantin Tsoyi, Cheryl Nickerson‐Nutter, Ivan O Rosas, Philip S Low
Формат: Стаття
Мова:English
Опубліковано: Springer Nature 2020-06-01
Серія:EMBO Molecular Medicine
Предмети:
bleomycin
folate receptor β
idiopathic pulmonary fibrosis
macrophages
toll‐like receptor 7
Онлайн доступ:https://doi.org/10.15252/emmm.202012034

Інтернет

https://doi.org/10.15252/emmm.202012034

Схожі ресурси