<em>In vitro</em> antimicrobial effect of the plant <em>Boldoa purpurascens Cav.</em> (Nitro) in the fimbria of <em>Escherichia coli</em>
<p class="western" style="margin-bottom: 0cm; line-height: 100%;" align="justify"><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><strong>Background</strong&...
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| Format: | Article |
| Language: | Spanish |
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Universidad de Ciencias Médicas de Las Tunas
2018-11-01
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| Series: | Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta |
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| Online Access: | http://revzoilomarinello.sld.cu/index.php/zmv/article/view/1623 |
| _version_ | 1818923658661330944 |
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| author | Carlos Manuel Jiménez-Martínez Dunia Ramos-López Yisell Urquiza-Yero |
| author_facet | Carlos Manuel Jiménez-Martínez Dunia Ramos-López Yisell Urquiza-Yero |
| author_sort | Carlos Manuel Jiménez-Martínez |
| collection | DOAJ |
| description | <p class="western" style="margin-bottom: 0cm; line-height: 100%;" align="justify"><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><strong>Background</strong></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">: the plant </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-GB"><em>Boldoa purpurascens Cav.</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"> (Nitro) has traditionally been considered useful for urinary tract diseases. It constitutes a therapeutic potential for the development of effective pharmaceutical forms.</span></span></span></p><p class="western" style="margin-bottom: 0cm; line-height: 100%;" align="justify"><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><strong>Objective</strong></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">: to evaluate the </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><em>in vitro</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"> antimicrobial effect of hydroalcoholic and aqueous extracts of the plant </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-GB"><em>Boldoa purpurascens Cav.</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">in the fimbria of </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><em>Escherichia coli</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">.</span></span></span></p><p class="western" style="margin-bottom: 0cm; line-height: 100%;" align="justify"><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><strong>Methods</strong></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">: a pharmacognostic study was carried out with ethanolic extracts at 30 %, 50 % and 70 % of the foliaceous and flowering spikes of the plant </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-GB"><em>Boldoa purpurascens Cav.</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">The extracts were prepared according to the extraction technique. The fundamental parameters of quality control for raw drug and extractions were assessed. In the microbiological study the fimbria of </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><em>Escherichia coli</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"> was assessed. The studies were conducted at the Provincial Pharmaceutical Laboratory of Las Tunas.</span></span></span></p><p class="western" style="margin-bottom: 0cm; line-height: 100%;" align="justify"><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><strong>Results</strong></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">: both the foliaceous and flowering spikes have medium solubility in ethanol at 30 % and 50 %; the pH had values very close to the neuter for the hydroalcoholic extracts at 30 % and 50 % of both spikes, compatible with the physiology of the human organism. The total solids in the 50 % extracts showed better results. The same extract, at 50 %, showed, at phytochemical screening, the presence of amino group, phenols, tannins, triterpenes and steroids, until dilution 1: 4. There was inhibition of the fimbrial expression with aqueous and hydroalcoholic extract at 30 % and at 50 % of the flowering spike.</span></span></span></p><p class="western" style="margin-bottom: 0.14cm; line-height: 100%;" align="justify"><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><strong>Conclusions</strong></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">: the aqueous and hydroalcoholic extracts of the flowering spikes showed antimicrobial activity in the fimbria of </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><em>Escherichia coli</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">.</span></span></span></p> |
| first_indexed | 2024-12-20T02:12:56Z |
| format | Article |
| id | doaj.art-6c2bee9773d64af4ae46522f310c683e |
| institution | Directory Open Access Journal |
| issn | 1029-3027 |
| language | Spanish |
| last_indexed | 2024-12-20T02:12:56Z |
| publishDate | 2018-11-01 |
| publisher | Universidad de Ciencias Médicas de Las Tunas |
| record_format | Article |
| series | Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta |
| spelling | doaj.art-6c2bee9773d64af4ae46522f310c683e2022-12-21T19:57:00ZspaUniversidad de Ciencias Médicas de Las TunasRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta1029-30272018-11-01441839<em>In vitro</em> antimicrobial effect of the plant <em>Boldoa purpurascens Cav.</em> (Nitro) in the fimbria of <em>Escherichia coli</em>Carlos Manuel Jiménez-Martínez0Dunia Ramos-López1Yisell Urquiza-Yero2Facultad de Ciencias Médicas “Dr.Zoilo Marinello Vidaurreta”. Universidad de Ciencias Médicas de Las Tunas. Las Tunas.Empresa de Farmacia y Optica. Las Tunas. Facultad de Ciencias Médicas “Dr.Zoilo Marinello Vidaurreta”. Universidad de Ciencias Médicas de Las Tunas. Las Tunas.Universidad de Ciencias Médicas de Las Tunas. Las Tunas.<p class="western" style="margin-bottom: 0cm; line-height: 100%;" align="justify"><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><strong>Background</strong></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">: the plant </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-GB"><em>Boldoa purpurascens Cav.</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"> (Nitro) has traditionally been considered useful for urinary tract diseases. It constitutes a therapeutic potential for the development of effective pharmaceutical forms.</span></span></span></p><p class="western" style="margin-bottom: 0cm; line-height: 100%;" align="justify"><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><strong>Objective</strong></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">: to evaluate the </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><em>in vitro</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"> antimicrobial effect of hydroalcoholic and aqueous extracts of the plant </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-GB"><em>Boldoa purpurascens Cav.</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">in the fimbria of </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><em>Escherichia coli</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">.</span></span></span></p><p class="western" style="margin-bottom: 0cm; line-height: 100%;" align="justify"><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><strong>Methods</strong></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">: a pharmacognostic study was carried out with ethanolic extracts at 30 %, 50 % and 70 % of the foliaceous and flowering spikes of the plant </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-GB"><em>Boldoa purpurascens Cav.</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">The extracts were prepared according to the extraction technique. The fundamental parameters of quality control for raw drug and extractions were assessed. In the microbiological study the fimbria of </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><em>Escherichia coli</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"> was assessed. The studies were conducted at the Provincial Pharmaceutical Laboratory of Las Tunas.</span></span></span></p><p class="western" style="margin-bottom: 0cm; line-height: 100%;" align="justify"><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><strong>Results</strong></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">: both the foliaceous and flowering spikes have medium solubility in ethanol at 30 % and 50 %; the pH had values very close to the neuter for the hydroalcoholic extracts at 30 % and 50 % of both spikes, compatible with the physiology of the human organism. The total solids in the 50 % extracts showed better results. The same extract, at 50 %, showed, at phytochemical screening, the presence of amino group, phenols, tannins, triterpenes and steroids, until dilution 1: 4. There was inhibition of the fimbrial expression with aqueous and hydroalcoholic extract at 30 % and at 50 % of the flowering spike.</span></span></span></p><p class="western" style="margin-bottom: 0.14cm; line-height: 100%;" align="justify"><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><strong>Conclusions</strong></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">: the aqueous and hydroalcoholic extracts of the flowering spikes showed antimicrobial activity in the fimbria of </span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US"><em>Escherichia coli</em></span></span></span><span style="font-family: Verdana,sans-serif;"><span style="font-size: small;"><span lang="en-US">.</span></span></span></p>http://revzoilomarinello.sld.cu/index.php/zmv/article/view/1623escherichia colinyctaginaceaeurinary tractmedicine, traditional |
| spellingShingle | Carlos Manuel Jiménez-Martínez Dunia Ramos-López Yisell Urquiza-Yero <em>In vitro</em> antimicrobial effect of the plant <em>Boldoa purpurascens Cav.</em> (Nitro) in the fimbria of <em>Escherichia coli</em> Revista Electrónica Dr. Zoilo E. Marinello Vidaurreta escherichia coli nyctaginaceae urinary tract medicine, traditional |
| title | <em>In vitro</em> antimicrobial effect of the plant <em>Boldoa purpurascens Cav.</em> (Nitro) in the fimbria of <em>Escherichia coli</em> |
| title_full | <em>In vitro</em> antimicrobial effect of the plant <em>Boldoa purpurascens Cav.</em> (Nitro) in the fimbria of <em>Escherichia coli</em> |
| title_fullStr | <em>In vitro</em> antimicrobial effect of the plant <em>Boldoa purpurascens Cav.</em> (Nitro) in the fimbria of <em>Escherichia coli</em> |
| title_full_unstemmed | <em>In vitro</em> antimicrobial effect of the plant <em>Boldoa purpurascens Cav.</em> (Nitro) in the fimbria of <em>Escherichia coli</em> |
| title_short | <em>In vitro</em> antimicrobial effect of the plant <em>Boldoa purpurascens Cav.</em> (Nitro) in the fimbria of <em>Escherichia coli</em> |
| title_sort | em in vitro em antimicrobial effect of the plant em boldoa purpurascens cav em nitro in the fimbria of em escherichia coli em |
| topic | escherichia coli nyctaginaceae urinary tract medicine, traditional |
| url | http://revzoilomarinello.sld.cu/index.php/zmv/article/view/1623 |
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