Impact of O-Acetylation on <i>S. flexneri</i> 1b and 2a O-Antigen Immunogenicity in Mice

Impact of O-Acetylation on <i>S. flexneri</i> 1b and 2a O-Antigen Immunogenicity in Mice

Shigellosis is a diarrheal disease caused prevalently by <i>Shigella flexneri</i> and <i>S. sonnei</i> and representing a major global health risk, particularly in developing countries. Bacterial O-antigen (OAg) is the primary target of the host immune response and modificati...

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Bibliographic Details
Main Authors: Vanessa Arato, Davide Oldrini, Luisa Massai, Gianmarco Gasperini, Francesca Necchi, Francesca Micoli
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Microorganisms
Subjects:
<i>Shigella flexneri</i>
O-antigen
O-acetylation
GMMA vaccine
Online Access:https://www.mdpi.com/2076-2607/9/11/2360

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