Neural correlates of affective theory of mind in medication-free nonsuicidal self-injury: An fMRI study
Emerging evidence indicates that emotion processing deficits are associated with nonsuicidal self-injury (NSSI). However, limited attention has been paid to the socio-affective functions of NSSI. In this study, we aimed to investigate the affective theory of mind (ToM) in medication-free individuals...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-07-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.850794/full |
| _version_ | 1818465824622510080 |
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| author | Hyeri Moon Gieun Nam Ji-Won Hur |
| author_facet | Hyeri Moon Gieun Nam Ji-Won Hur |
| author_sort | Hyeri Moon |
| collection | DOAJ |
| description | Emerging evidence indicates that emotion processing deficits are associated with nonsuicidal self-injury (NSSI). However, limited attention has been paid to the socio-affective functions of NSSI. In this study, we aimed to investigate the affective theory of mind (ToM) in medication-free individuals engaging in NSSI at both behavioral and neural levels. Twenty-eight individuals (mean age = 22.96 years) who engaged in NSSI and 38 age-, sex-, and IQ-matched controls (mean age = 22.79 years) underwent functional magnetic resonance imaging while performing the “Reading the Mind in the Eyes Test” (RMET). All participants also completed the Difficulties in Emotion Regulation Scale (DERS), Toronto Alexithymia Scale (TAS-20), and Beck Scale for Suicide Ideation (BSI). Although we did not find significant group differences in the RMET performance, the NSSI group, relative to the controls, exhibited significantly greater left medial superior frontal lobe activation and decreased right angular gyrus activation than did the control group. Reduced right angular gyrus activity was related to higher DERS and TAS scores across all participants. Our findings provide new evidence for aberrant neural processing of affective ToM in self-injurers. Future studies in developing intervention protocols for NSSI should focus on the multifaceted phases of socio-affective processing. |
| first_indexed | 2024-04-13T20:50:51Z |
| format | Article |
| id | doaj.art-6c2e8988d4db4f42950e4aa9d4a22bea |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-04-13T20:50:51Z |
| publishDate | 2022-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-6c2e8988d4db4f42950e4aa9d4a22bea2022-12-22T02:30:32ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-07-011310.3389/fpsyt.2022.850794850794Neural correlates of affective theory of mind in medication-free nonsuicidal self-injury: An fMRI studyHyeri Moon0Gieun Nam1Ji-Won Hur2School of Psychology, Korea University, Seoul, South KoreaDepartment of Psychology, Chung-Ang University, Seoul, South KoreaSchool of Psychology, Korea University, Seoul, South KoreaEmerging evidence indicates that emotion processing deficits are associated with nonsuicidal self-injury (NSSI). However, limited attention has been paid to the socio-affective functions of NSSI. In this study, we aimed to investigate the affective theory of mind (ToM) in medication-free individuals engaging in NSSI at both behavioral and neural levels. Twenty-eight individuals (mean age = 22.96 years) who engaged in NSSI and 38 age-, sex-, and IQ-matched controls (mean age = 22.79 years) underwent functional magnetic resonance imaging while performing the “Reading the Mind in the Eyes Test” (RMET). All participants also completed the Difficulties in Emotion Regulation Scale (DERS), Toronto Alexithymia Scale (TAS-20), and Beck Scale for Suicide Ideation (BSI). Although we did not find significant group differences in the RMET performance, the NSSI group, relative to the controls, exhibited significantly greater left medial superior frontal lobe activation and decreased right angular gyrus activation than did the control group. Reduced right angular gyrus activity was related to higher DERS and TAS scores across all participants. Our findings provide new evidence for aberrant neural processing of affective ToM in self-injurers. Future studies in developing intervention protocols for NSSI should focus on the multifaceted phases of socio-affective processing.https://www.frontiersin.org/articles/10.3389/fpsyt.2022.850794/fullnonsuicidal self-injuryaffective ToMtheory of mindfMRIReading the Mind in the Eyes Test |
| spellingShingle | Hyeri Moon Gieun Nam Ji-Won Hur Neural correlates of affective theory of mind in medication-free nonsuicidal self-injury: An fMRI study Frontiers in Psychiatry nonsuicidal self-injury affective ToM theory of mind fMRI Reading the Mind in the Eyes Test |
| title | Neural correlates of affective theory of mind in medication-free nonsuicidal self-injury: An fMRI study |
| title_full | Neural correlates of affective theory of mind in medication-free nonsuicidal self-injury: An fMRI study |
| title_fullStr | Neural correlates of affective theory of mind in medication-free nonsuicidal self-injury: An fMRI study |
| title_full_unstemmed | Neural correlates of affective theory of mind in medication-free nonsuicidal self-injury: An fMRI study |
| title_short | Neural correlates of affective theory of mind in medication-free nonsuicidal self-injury: An fMRI study |
| title_sort | neural correlates of affective theory of mind in medication free nonsuicidal self injury an fmri study |
| topic | nonsuicidal self-injury affective ToM theory of mind fMRI Reading the Mind in the Eyes Test |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.850794/full |
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