Natural Compounds in the Battle against Microorganisms—Linalool
The purpose of this article is to present recent studies on the antimicrobial properties of linalool, the mechanism of action on cells and detoxification processes. The current trend of employing compounds present in essential oils to support antibiotic therapy is becoming increasingly popular. Natu...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-10-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/27/20/6928 |
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| author | Wanda Mączka Anna Duda-Madej Małgorzata Grabarczyk Katarzyna Wińska |
| author_facet | Wanda Mączka Anna Duda-Madej Małgorzata Grabarczyk Katarzyna Wińska |
| author_sort | Wanda Mączka |
| collection | DOAJ |
| description | The purpose of this article is to present recent studies on the antimicrobial properties of linalool, the mechanism of action on cells and detoxification processes. The current trend of employing compounds present in essential oils to support antibiotic therapy is becoming increasingly popular. Naturally occurring monoterpene constituents of essential oils are undergoing detailed studies to understand their detailed effects on the human body, both independently and in doses correlated with currently used pharmaceuticals. One such compound is linalool, which is commonly found in many herbs and is used to flavor black tea. This compound is an excellent fragrance additive for cosmetics, enhancing the preservative effect of the formulations used in them or acting as an anti-inflammatory on mild skin lesions. Previous studies have shown that it is extremely important due to its broad spectrum of biological activities, i.e., antioxidant, anti-inflammatory, anticancer, cardioprotective and antimicrobial. Among opportunistic hospital strains, it is most active against Gram-negative bacteria. The mechanism of action of linalool against microorganisms is still under intensive investigation. One of the key aspects of linalool research is biotransformation, through which its susceptibility to detoxification processes is determined. |
| first_indexed | 2024-03-09T19:42:26Z |
| format | Article |
| id | doaj.art-6c2efee574a6482bb0b12a8a0187eaae |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T19:42:26Z |
| publishDate | 2022-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-6c2efee574a6482bb0b12a8a0187eaae2023-11-24T01:34:01ZengMDPI AGMolecules1420-30492022-10-012720692810.3390/molecules27206928Natural Compounds in the Battle against Microorganisms—LinaloolWanda Mączka0Anna Duda-Madej1Małgorzata Grabarczyk2Katarzyna Wińska3Department of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, PolandDepartment of Microbiology, Wroclaw Medical University, Chałubińskiego 4, 50-368 Wrocław, PolandDepartment of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, PolandDepartment of Food Chemistry and Biocatalysis, Wrocław University of Environmental and Life Sciences, Norwida 25, 50-375 Wrocław, PolandThe purpose of this article is to present recent studies on the antimicrobial properties of linalool, the mechanism of action on cells and detoxification processes. The current trend of employing compounds present in essential oils to support antibiotic therapy is becoming increasingly popular. Naturally occurring monoterpene constituents of essential oils are undergoing detailed studies to understand their detailed effects on the human body, both independently and in doses correlated with currently used pharmaceuticals. One such compound is linalool, which is commonly found in many herbs and is used to flavor black tea. This compound is an excellent fragrance additive for cosmetics, enhancing the preservative effect of the formulations used in them or acting as an anti-inflammatory on mild skin lesions. Previous studies have shown that it is extremely important due to its broad spectrum of biological activities, i.e., antioxidant, anti-inflammatory, anticancer, cardioprotective and antimicrobial. Among opportunistic hospital strains, it is most active against Gram-negative bacteria. The mechanism of action of linalool against microorganisms is still under intensive investigation. One of the key aspects of linalool research is biotransformation, through which its susceptibility to detoxification processes is determined.https://www.mdpi.com/1420-3049/27/20/6928linaloolmonoterpeneantimicrobialbiotransformation |
| spellingShingle | Wanda Mączka Anna Duda-Madej Małgorzata Grabarczyk Katarzyna Wińska Natural Compounds in the Battle against Microorganisms—Linalool Molecules linalool monoterpene antimicrobial biotransformation |
| title | Natural Compounds in the Battle against Microorganisms—Linalool |
| title_full | Natural Compounds in the Battle against Microorganisms—Linalool |
| title_fullStr | Natural Compounds in the Battle against Microorganisms—Linalool |
| title_full_unstemmed | Natural Compounds in the Battle against Microorganisms—Linalool |
| title_short | Natural Compounds in the Battle against Microorganisms—Linalool |
| title_sort | natural compounds in the battle against microorganisms linalool |
| topic | linalool monoterpene antimicrobial biotransformation |
| url | https://www.mdpi.com/1420-3049/27/20/6928 |
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