Graphene Oxide (GO) Materials—Applications and Toxicity on Living Organisms and Environment

Graphene-based materials have attracted much attention due to their fascinating properties such as hydrophilicity, high dispersion in aqueous media, robust size, high biocompatibility, and surface functionalization ability due to the presence of functional groups and interactions with biomolecules s...

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Main Authors: Aminah N. Ghulam, Otávio A. L. dos Santos, Layla Hazeem, Bianca Pizzorno Backx, Mohamed Bououdina, Stefano Bellucci
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Journal of Functional Biomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4983/13/2/77
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author Aminah N. Ghulam
Otávio A. L. dos Santos
Layla Hazeem
Bianca Pizzorno Backx
Mohamed Bououdina
Stefano Bellucci
author_facet Aminah N. Ghulam
Otávio A. L. dos Santos
Layla Hazeem
Bianca Pizzorno Backx
Mohamed Bououdina
Stefano Bellucci
author_sort Aminah N. Ghulam
collection DOAJ
description Graphene-based materials have attracted much attention due to their fascinating properties such as hydrophilicity, high dispersion in aqueous media, robust size, high biocompatibility, and surface functionalization ability due to the presence of functional groups and interactions with biomolecules such as proteins and nucleic acid. Modified methods were developed for safe, direct, inexpensive, and eco-friendly synthesis. However, toxicity to the environment and animal health has been reported, raising concerns about their utilization. This review focuses primarily on the synthesis methods of graphene-based materials already developed and the unique properties that make them so interesting for different applications. Different applications are presented and discussed with particular emphasis on biological fields. Furthermore, antimicrobial potential and the factors that affect this activity are reviewed. Finally, questions related to toxicity to the environment and living organisms are revised by highlighting factors that may interfere with it.
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spelling doaj.art-6c3b72a992894826944d2a162c36b6f12023-11-23T17:19:50ZengMDPI AGJournal of Functional Biomaterials2079-49832022-06-011327710.3390/jfb13020077Graphene Oxide (GO) Materials—Applications and Toxicity on Living Organisms and EnvironmentAminah N. Ghulam0Otávio A. L. dos Santos1Layla Hazeem2Bianca Pizzorno Backx3Mohamed Bououdina4Stefano Bellucci5Department of Biology, College of Science, University of Bahrain, Zallaq P.O. Box 32038, BahrainInstituto de Bioquímica Médica, Universidade Federal do Rio de Janeiro, Rio de Janeiro 21941-902, BrazilDepartment of Biology, College of Science, University of Bahrain, Zallaq P.O. Box 32038, BahrainNumpex-Bio, Universidade Federal do Rio de Janeiro, Campus Duque de Caxias, Duque de Caxias 25245-390, BrazilDepartment of Mathematics and Sciences, Faculty of Humanities and Sciences, Prince Sultan University, Riyadh 11586, Saudi ArabiaINFN-Laboratori Nazionali di Frascati, Via E. Fermi 54, 00044 Frascati, ItalyGraphene-based materials have attracted much attention due to their fascinating properties such as hydrophilicity, high dispersion in aqueous media, robust size, high biocompatibility, and surface functionalization ability due to the presence of functional groups and interactions with biomolecules such as proteins and nucleic acid. Modified methods were developed for safe, direct, inexpensive, and eco-friendly synthesis. However, toxicity to the environment and animal health has been reported, raising concerns about their utilization. This review focuses primarily on the synthesis methods of graphene-based materials already developed and the unique properties that make them so interesting for different applications. Different applications are presented and discussed with particular emphasis on biological fields. Furthermore, antimicrobial potential and the factors that affect this activity are reviewed. Finally, questions related to toxicity to the environment and living organisms are revised by highlighting factors that may interfere with it.https://www.mdpi.com/2079-4983/13/2/77graphene derivativeshealthenvironmentcytotoxicity
spellingShingle Aminah N. Ghulam
Otávio A. L. dos Santos
Layla Hazeem
Bianca Pizzorno Backx
Mohamed Bououdina
Stefano Bellucci
Graphene Oxide (GO) Materials—Applications and Toxicity on Living Organisms and Environment
Journal of Functional Biomaterials
graphene derivatives
health
environment
cytotoxicity
title Graphene Oxide (GO) Materials—Applications and Toxicity on Living Organisms and Environment
title_full Graphene Oxide (GO) Materials—Applications and Toxicity on Living Organisms and Environment
title_fullStr Graphene Oxide (GO) Materials—Applications and Toxicity on Living Organisms and Environment
title_full_unstemmed Graphene Oxide (GO) Materials—Applications and Toxicity on Living Organisms and Environment
title_short Graphene Oxide (GO) Materials—Applications and Toxicity on Living Organisms and Environment
title_sort graphene oxide go materials applications and toxicity on living organisms and environment
topic graphene derivatives
health
environment
cytotoxicity
url https://www.mdpi.com/2079-4983/13/2/77
work_keys_str_mv AT aminahnghulam grapheneoxidegomaterialsapplicationsandtoxicityonlivingorganismsandenvironment
AT otavioaldossantos grapheneoxidegomaterialsapplicationsandtoxicityonlivingorganismsandenvironment
AT laylahazeem grapheneoxidegomaterialsapplicationsandtoxicityonlivingorganismsandenvironment
AT biancapizzornobackx grapheneoxidegomaterialsapplicationsandtoxicityonlivingorganismsandenvironment
AT mohamedbououdina grapheneoxidegomaterialsapplicationsandtoxicityonlivingorganismsandenvironment
AT stefanobellucci grapheneoxidegomaterialsapplicationsandtoxicityonlivingorganismsandenvironment