COVID-19 vaccination: Is it a matter of concern?
Background: COVID-19 vaccination is still a matter of concern among the public since its inception. Primary care physicians being in prime position can share accurate and ample information about COVID-19 vaccination so we estimated proportion and determinants of adverse events following immunization...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2022-01-01
|
| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2022;volume=11;issue=6;spage=2431;epage=2436;aulast=Kushwaha |
| _version_ | 1828790592616792064 |
|---|---|
| author | Poonam Kushwaha Ashish Pundhir Anju Gahlot |
| author_facet | Poonam Kushwaha Ashish Pundhir Anju Gahlot |
| author_sort | Poonam Kushwaha |
| collection | DOAJ |
| description | Background: COVID-19 vaccination is still a matter of concern among the public since its inception. Primary care physicians being in prime position can share accurate and ample information about COVID-19 vaccination so we estimated proportion and determinants of adverse events following immunization (AEFI) with Covishield vaccine, vaccination and reasons of non-vaccination. Methods: A cross-sectional study was conducted from January to April 2021. Data collection was done by using data capture tool Epicollect-5. Regression analysis was performed to evaluate the association of AEFI and vaccine acceptance with various demographic variables. Results: Of 520 subjects, 408 got vaccinated, and of these 125 (30.6%) developed AEFI. Females without AEFI had lower median age than females having AEFI. Only religion (aOR = 5.311; 95%CI: 1.216–23.1) was significantly associated with AEFI. Education (aOR = 0.399; 95%CI: 0.199–0.799), marital status (aOR = 0.459; 95%CI: 0.245–0.858), and religion (aOR = 3.874; 95%CI: 1.96–7.648) were significantly associated with vaccination. Most common local AEFIs were inflammation (46; 36.8%) followed by lump (10; 8%) at the site of injection. Most common systemic AEFI were fever (87; 69.6%), feeling unwell (65; 52%), generalized weakness/fatigue (30; 20%), tiredness (26; 20.8%), flu-like symptoms (12; 9.6%), dizziness (10; 8%), headache (8; 6.4%) and gastrointestinal events (7; 5.6%). Conclusion: Most of the AEFI were mild and transient, resolved without any medical management. This study warrants active reporting of AEFI, public release of safety, and efficacy data. Primary care physicians can play a pivotal role by targeted awareness campaigns and trust-building activities to alleviate fear and anxiety related to vaccine. |
| first_indexed | 2024-12-12T01:33:13Z |
| format | Article |
| id | doaj.art-6c3c88b65b0349ecae49b5164713ef7b |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-12-12T01:33:13Z |
| publishDate | 2022-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-6c3c88b65b0349ecae49b5164713ef7b2022-12-22T00:42:54ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632022-01-011162431243610.4103/jfmpc.jfmpc_1778_21COVID-19 vaccination: Is it a matter of concern?Poonam KushwahaAshish PundhirAnju GahlotBackground: COVID-19 vaccination is still a matter of concern among the public since its inception. Primary care physicians being in prime position can share accurate and ample information about COVID-19 vaccination so we estimated proportion and determinants of adverse events following immunization (AEFI) with Covishield vaccine, vaccination and reasons of non-vaccination. Methods: A cross-sectional study was conducted from January to April 2021. Data collection was done by using data capture tool Epicollect-5. Regression analysis was performed to evaluate the association of AEFI and vaccine acceptance with various demographic variables. Results: Of 520 subjects, 408 got vaccinated, and of these 125 (30.6%) developed AEFI. Females without AEFI had lower median age than females having AEFI. Only religion (aOR = 5.311; 95%CI: 1.216–23.1) was significantly associated with AEFI. Education (aOR = 0.399; 95%CI: 0.199–0.799), marital status (aOR = 0.459; 95%CI: 0.245–0.858), and religion (aOR = 3.874; 95%CI: 1.96–7.648) were significantly associated with vaccination. Most common local AEFIs were inflammation (46; 36.8%) followed by lump (10; 8%) at the site of injection. Most common systemic AEFI were fever (87; 69.6%), feeling unwell (65; 52%), generalized weakness/fatigue (30; 20%), tiredness (26; 20.8%), flu-like symptoms (12; 9.6%), dizziness (10; 8%), headache (8; 6.4%) and gastrointestinal events (7; 5.6%). Conclusion: Most of the AEFI were mild and transient, resolved without any medical management. This study warrants active reporting of AEFI, public release of safety, and efficacy data. Primary care physicians can play a pivotal role by targeted awareness campaigns and trust-building activities to alleviate fear and anxiety related to vaccine.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2022;volume=11;issue=6;spage=2431;epage=2436;aulast=Kushwahaadverse event following vaccinationcovid-19indianonacceptancepandemicvaccine hesitancy |
| spellingShingle | Poonam Kushwaha Ashish Pundhir Anju Gahlot COVID-19 vaccination: Is it a matter of concern? Journal of Family Medicine and Primary Care adverse event following vaccination covid-19 india nonacceptance pandemic vaccine hesitancy |
| title | COVID-19 vaccination: Is it a matter of concern? |
| title_full | COVID-19 vaccination: Is it a matter of concern? |
| title_fullStr | COVID-19 vaccination: Is it a matter of concern? |
| title_full_unstemmed | COVID-19 vaccination: Is it a matter of concern? |
| title_short | COVID-19 vaccination: Is it a matter of concern? |
| title_sort | covid 19 vaccination is it a matter of concern |
| topic | adverse event following vaccination covid-19 india nonacceptance pandemic vaccine hesitancy |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2022;volume=11;issue=6;spage=2431;epage=2436;aulast=Kushwaha |
| work_keys_str_mv | AT poonamkushwaha covid19vaccinationisitamatterofconcern AT ashishpundhir covid19vaccinationisitamatterofconcern AT anjugahlot covid19vaccinationisitamatterofconcern |