A case of multisystem inflammatory syndrome in an African adolescent male: case report
Since late April 2020 a syndrome now termed Multisystem Inflammatory Syndrome in Children (MIS-C) has been seen in children and adolescents in association with COVID-19 infection. The definition of MIS-C involves fever, organ dysfunction and laboratory confirmation of inflammation in the context of...
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| Format: | Article |
| Language: | English |
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The Pan African Medical Journal
2021-02-01
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| Series: | The Pan African Medical Journal |
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| Online Access: |
https://www.panafrican-med-journal.com/content/article/38/174/pdf/174.pdf
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| _version_ | 1818917105626513408 |
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| author | Pramodhini Moodley Jacob Merika Letlhoo Tsitsi Denasha Lavanya Reddy Mohith Debising Claudia Ickinger |
| author_facet | Pramodhini Moodley Jacob Merika Letlhoo Tsitsi Denasha Lavanya Reddy Mohith Debising Claudia Ickinger |
| author_sort | Pramodhini Moodley |
| collection | DOAJ |
| description | Since late April 2020 a syndrome now termed Multisystem Inflammatory Syndrome in Children (MIS-C) has been seen in children and adolescents in association with COVID-19 infection. The definition of MIS-C involves fever, organ dysfunction and laboratory confirmation of inflammation in the context of laboratory or epidemiological evidence of SARS-CoV-2 infection in a patient under 21 years of age. Notably cases are now being identified in adults termed Multisystem Inflammatory syndrome in Adults(MIS-A). Few cases have been reported in sub-Saharan Africa. We report a case of a young African male presenting with a maculopapular rash, persistent fever, elevation in inflammatory markers and a sudden, significant deterioration in cardiac function resulting in cardiogenic shock. The patient responded to intravenous steroids , intravenous immunoglobulin and background inotropic support. The recognition of this disease entity proves even more crucial now amidst the ongoing global wave of COVID-19 infection. It is paramount to identify these patients early, leading to prompt treatment avoiding further morbidity and mortality. |
| first_indexed | 2024-12-20T00:28:47Z |
| format | Article |
| id | doaj.art-6c3de8def6d84e55b5e93d6dec918ff5 |
| institution | Directory Open Access Journal |
| issn | 1937-8688 1937-8688 |
| language | English |
| last_indexed | 2024-12-20T00:28:47Z |
| publishDate | 2021-02-01 |
| publisher | The Pan African Medical Journal |
| record_format | Article |
| series | The Pan African Medical Journal |
| spelling | doaj.art-6c3de8def6d84e55b5e93d6dec918ff52022-12-21T20:00:00ZengThe Pan African Medical JournalThe Pan African Medical Journal1937-86881937-86882021-02-013817410.11604/pamj.2021.38.174.2791027910A case of multisystem inflammatory syndrome in an African adolescent male: case reportPramodhini Moodley0Jacob Merika Letlhoo Tsitsi1Denasha Lavanya Reddy2Mohith Debising3Claudia Ickinger4 Faculty of Health Sciences, University of the Witwatersrand, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Soweto, Johannesburg, South Africa Faculty of Health Sciences, University of the Witwatersrand, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Soweto, Johannesburg, South Africa Faculty of Health Sciences, University of the Witwatersrand, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Soweto, Johannesburg, South Africa Faculty of Health Sciences, University of the Witwatersrand, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Soweto, Johannesburg, South Africa Faculty of Health Sciences, University of the Witwatersrand, Department of Internal Medicine, Chris Hani Baragwanath Academic Hospital, Soweto, Johannesburg, South Africa Since late April 2020 a syndrome now termed Multisystem Inflammatory Syndrome in Children (MIS-C) has been seen in children and adolescents in association with COVID-19 infection. The definition of MIS-C involves fever, organ dysfunction and laboratory confirmation of inflammation in the context of laboratory or epidemiological evidence of SARS-CoV-2 infection in a patient under 21 years of age. Notably cases are now being identified in adults termed Multisystem Inflammatory syndrome in Adults(MIS-A). Few cases have been reported in sub-Saharan Africa. We report a case of a young African male presenting with a maculopapular rash, persistent fever, elevation in inflammatory markers and a sudden, significant deterioration in cardiac function resulting in cardiogenic shock. The patient responded to intravenous steroids , intravenous immunoglobulin and background inotropic support. The recognition of this disease entity proves even more crucial now amidst the ongoing global wave of COVID-19 infection. It is paramount to identify these patients early, leading to prompt treatment avoiding further morbidity and mortality. https://www.panafrican-med-journal.com/content/article/38/174/pdf/174.pdf multisystem inflammatory syndromechildrenafricansars-cov-2case report |
| spellingShingle | Pramodhini Moodley Jacob Merika Letlhoo Tsitsi Denasha Lavanya Reddy Mohith Debising Claudia Ickinger A case of multisystem inflammatory syndrome in an African adolescent male: case report The Pan African Medical Journal multisystem inflammatory syndrome children african sars-cov-2 case report |
| title | A case of multisystem inflammatory syndrome in an African adolescent male: case report |
| title_full | A case of multisystem inflammatory syndrome in an African adolescent male: case report |
| title_fullStr | A case of multisystem inflammatory syndrome in an African adolescent male: case report |
| title_full_unstemmed | A case of multisystem inflammatory syndrome in an African adolescent male: case report |
| title_short | A case of multisystem inflammatory syndrome in an African adolescent male: case report |
| title_sort | case of multisystem inflammatory syndrome in an african adolescent male case report |
| topic | multisystem inflammatory syndrome children african sars-cov-2 case report |
| url |
https://www.panafrican-med-journal.com/content/article/38/174/pdf/174.pdf
|
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