Low sequence diversity of the prion protein gene (PRNP) in wild deer and goat species from Spain

Low sequence diversity of the prion protein gene (PRNP) in wild deer and goat species from Spain

Abstract The first European cases of chronic wasting disease (CWD) in free-ranging reindeer and wild elk were confirmed in Norway in 2016 highlighting the urgent need to understand transmissible spongiform encephalopathies (TSEs) in the context of European deer species and the many individual popula...

Full description

Bibliographic Details
Main Authors:	José Luis Pitarch, Helen Caroline Raksa, María Cruz Arnal, Miguel Revilla, David Martínez, Daniel Fernández de Luco, Juan José Badiola, Wilfred Goldmann, Cristina Acín
Format:	Article
Language:	English
Published:	BMC 2018-04-01
Series:	Veterinary Research
Online Access:	http://link.springer.com/article/10.1186/s13567-018-0528-8

Similar Items

Variation in the prion protein gene (PRNP) sequence of wild deer in Great Britain and mainland Europe
by: Amy L. Robinson, et al.
Published: (2019-07-01)

Novel polymorphisms in the prion protein gene (PRNP) and stability of the resultant prion protein in different horse breeds
by: Diego Sola, et al.
Published: (2023-10-01)

Estimating sequence diversity of prion protein gene (PRNP) in Portuguese populations of two cervid species: red deer and fallow deer
by: Jorge C. Pereira, et al.
Published: (2023-12-01)

Genetic Variation in the Prion Protein Gene (<i>PRNP</i>) of Two Tunisian Goat Populations
by: Samia Kdidi, et al.
Published: (2021-05-01)

Prion gene (<it>PRNP</it>) haplotype variation in United States goat breeds <it>(Open Access publication)</it>
by: O'rourke Katherine, et al.
Published: (2008-09-01)

Analysis of differences in prion protein gene (PRNP) polymorphisms between Algerian and Southern Italy's goats
by: Khaled Fantazi, et al.
Published: (2018-07-01)

Polymorphism of prion protein gene (PRNP) in Nigerian sheep
by: Adeniyi C. Adeola, et al.
Published: (2023-12-01)

Extrapolating the susceptibility of Eld’s deer (Rucervus eldii thamin) to chronic wasting disease from prion protein gene (PRNP) polymorphisms
by: Tolulope I.N. Perrin-Stowe, et al.
Published: (2022-10-01)

Functional and structural differences between the prion protein from two alleles prnp(a) and prnp(b) of mouse.
by: Brown, DR, et al.
Published: (2000)

Prion protein gene variability in Spanish goats. Inference through susceptibility to classical scrapie strains and pathogenic distribution of peripheral PrP(sc.).
by: Cristina Acín, et al.
Published: (2013-01-01)

Preventive or promotive effects of PRNP polymorphic heterozygosity on the onset of prion disease
by: Hideaki Kai, et al.
Published: (2023-03-01)

Knockdown of the bovine prion gene PRNP by RNA interference (RNAi) technology
by: Wongsrikeao Pimprapar, et al.
Published: (2007-07-01)

Characterization of mutations in PRNP (prion) gene and their possible roles in neurodegenerative diseases
by: Bagyinszky E, et al.
Published: (2018-08-01)

Capture myopathy in red deer and wild goat
by: Mirian, J., et al.
Published: (2011-12-01)

Identification of Prion Disease-Related Somatic Mutations in the Prion Protein Gene (<i>PRNP</i>) in Cancer Patients
by: Yong-Chan Kim, et al.
Published: (2020-06-01)

Disparate Modes of Evolution Shaped Modern Prion (PRNP) and Prion-Related Doppel (PRND) Variation in Domestic Cattle.
by: Brian W Brunelle, et al.
Published: (2016-01-01)

A case report of genetic prion disease with two different PRNP variants
by: Megan Piazza, et al.
Published: (2020-03-01)

Polymorphism of the prion protein gene (PRNP) in Polish Merino and Suffolk sheep flocks
by: Roman Niżnikowski, et al.
Published: (2020-06-01)

Caprine PRNP polymorphisms N146S and Q222K are associated with proteolytic cleavage of PrPC
by: Sally A. Madsen-Bouterse, et al.
Published: (2021-06-01)

Lions and prions and deer demise.
by: Michael W Miller, et al.
Published: (2008-01-01)

Novel Polymorphisms and Genetic Characteristics of the Prion Protein Gene (<i>PRNP</i>) in Dogs—A Resistant Animal of Prion Disease
by: Dong-Ju Kim, et al.
Published: (2020-06-01)

The 5' flanking region and intron1 of the bovine prion protein gene (PRNP) are responsible for negative feedback regulation of the prion protein.
by: Guangai Xue, et al.
Published: (2012-01-01)

Comparative Susceptibility of Sheep of Different Origins, Breeds and PRNP Genotypes to Challenge with Bovine Spongiform Encephalopathy and Scrapie.
by: Fiona Houston, et al.
Published: (2015-01-01)

The first report of polymorphisms of the prion protein gene (PRNP) in Pekin ducks (Anas platyrhynchos domestica)
by: Min-Ju Jeong, et al.
Published: (2023-11-01)

First report of a novel polymorphism and genetic characteristics of the leporine prion protein (PRNP) gene
by: Dong-Ju Kim, et al.
Published: (2023-09-01)

Homozygous R136S mutation in PRNP gene causes inherited early onset prion disease
by: Teresa Ximelis, et al.
Published: (2021-10-01)

Predicting the impact of selection for scrapie resistance on PRNP genotype frequencies in goats
by: Paola Sacchi, et al.
Published: (2018-03-01)

Lack of prion accumulation in lymphoid tissues of PRNP ARQ/ARR sheep intracranially inoculated with the agent of scrapie.
by: Justin J Greenlee, et al.
Published: (2014-01-01)

Early-onset Alzheimer’s disease patient with prion (PRNP) p.Val180Ile mutation
by: Bagyinszky E, et al.
Published: (2019-07-01)

Estimating relative CWD susceptibility and disease progression in farmed white-tailed deer with rare PRNP alleles.
by: Nicholas J Haley, et al.
Published: (2019-01-01)

Novel Single Nucleotide Polymorphisms (SNPs) and Genetic Features of the Prion Protein Gene (PRNP) in Quail (Coturnix japonica)
by: Yoonhee Kim, et al.
Published: (2022-05-01)

Single nucleotide polymorphisms (SNPs) in the open reading frame (ORF) of prion protein gene (PRNP) in Nigerian livestock species
by: Adeniyi C. Adeola, et al.
Published: (2024-02-01)

Novel Polymorphisms and Genetic Features of the Prion Protein Gene (<i>PRNP</i>) in Cats, Hosts of Feline Spongiform Encephalopathy
by: Hyeon-Ho Kim, et al.
Published: (2020-12-01)

Caprine prion gene polymorphisms are associated with decreased incidence of classical scrapie in goat herds in the United Kingdom
by: Goldmann Wilfred, et al.
Published: (2011-10-01)

The First Report of the Prion Protein Gene (<i>PRNP</i>) Sequence in Pekin Ducks (<i>Anas platyrhynchos domestica</i>): The Potential Prion Disease Susceptibility in Ducks
by: Min-Ju Jeong, et al.
Published: (2021-01-01)

Selective Breeding for Disease-Resistant <i>PRNP</i> Variants to Manage Chronic Wasting Disease in Farmed Whitetail Deer
by: Nicholas Haley, et al.
Published: (2021-09-01)

Rapid antemortem detection of CWD prions in deer saliva.
by: Davin M Henderson, et al.
Published: (2013-01-01)

Prion protein polymorphisms associated with reduced CWD susceptibility limit peripheral PrPCWD deposition in orally infected white-tailed deer
by: Alicia Otero, et al.
Published: (2019-02-01)

Susceptibility to scrapie and disease phenotype in sheep: cross-<it>PRNP</it> genotype experimental transmissions with natural sources
by: González Lorenzo, et al.
Published: (2012-07-01)

<i>PRNP</i> Polymorphisms in Eight Local Goat Populations/Breeds from Central and Southern Italy
by: Martina Torricelli, et al.
Published: (2021-01-01)